PDB: 217686 件ウェブページステータス検索Chemie searchBIRD

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7PRP	Crystal Structure of the B subunit of heat labile enterotoxin LT-IIc from Escherichia coli in apo form 分子名称: FORMIC ACID, Heat-labile enterotoxin IIA, B chain, ... 著者 Varrot, A. 登録日 2021-09-22 公開日 2021-12-08 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Characterization of the ganglioside recognition profile of Escherichia coli heat-labile enterotoxin LT-IIc. Glycobiology, 32, 2022
6U06	Discovery of Lysine-Targeted eIF4E Inhibitors through Covalent Docking 分子名称: 3-{[(4-cyanophenyl)methyl](1-oxo-1,2-dihydroisoquinolin-7-yl)sulfamoyl}benzene-1-sulfonyl fluoride, Eukaryotic translation initiation factor 4E 著者 Wan, X.B, Shoichet, B.K, Taunton, J. 登録日 2019-08-13 公開日 2019-10-16 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Discovery of Lysine-Targeted eIF4E Inhibitors through Covalent Docking. J.Am.Chem.Soc., 142, 2020
1AGK	THE SOLUTION NMR STRUCTURE OF AN (R)-A-(N6-ADENYL)-STYRENE OXIDE-RAS61 OLIGODEOXYNUCLEOTIDE MODIFIED AT THE SECOND POSITION OF THE CODON 61 REGION, MINIMIZED AVERAGE STRUCTURE 分子名称: DNA (5'-D(*CP*GP*GP*AP*CP*RP*AP*GP*AP*AP*G)-3'), DNA (5'-D(*CP*TP*TP*CP*TP*TP*GP*TP*CP*CP*G)-3') 著者 Feng, B, Stone, M.P. 登録日 1997-03-25 公開日 1997-08-20 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Major groove (R)-alpha-(N6-adenyl)styrene oxide adducts in an oligodeoxynucleotide containing the human N-ras codon 61 sequence: conformations of the R(61,2) and R(61,3) sequence isomers from 1H NMR. Biochemistry, 34, 1995
5ZWO	Cryo-EM structure of the yeast B complex at average resolution of 3.9 angstrom 分子名称: 13 kDa ribonucleoprotein-associated protein, 23 kDa U4/U6.U5 small nuclear ribonucleoprotein component, 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, ... 著者 Bai, R, Wan, R, Yan, C, Shi, Y. 登録日 2018-05-16 公開日 2018-08-29 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation Science, 360, 2018
1AGO	THE SOLUTION NMR STRUCTURE OF AN (S)-A-(N6-ADENYL)-STYRENE OXIDE-RAS61 OLIGODEOXYNUCLEOTIDE MODIFIED AT THE THIRD POSITION OF THE CODON 61 REGION, MINIMIZED AVERAGE STRUCTURE 分子名称: DNA (5'-D(*CP*GP*GP*AP*CP*AP*YP*GP*AP*AP*G)-3'), DNA (5'-D(*CP*TP*TP*CP*TP*TP*GP*TP*CP*CP*G)-3') 著者 Feng, B, Stone, M.P. 登録日 1997-03-25 公開日 1997-08-20 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Major groove (S)-alpha-(N6-adenyl)styrene oxide adducts in an oligodeoxynucleotide containing the human N-ras codon 61 sequence: conformations of the S(61,2) and S(61,3) sequence isomers from 1H NMR. Biochemistry, 35, 1996
6RJ5	Crystal structure of PHGDH in complex with compound 39 分子名称: 2-methyl-~{N}-[(1~{R})-1-[4-(methylsulfonylcarbamoyl)phenyl]ethyl]-5-phenyl-pyrazole-3-carboxamide, D-3-phosphoglycerate dehydrogenase, SULFATE ION 著者 Bader, G, Wolkerstorfer, B, Zoephel, A. 登録日 2019-04-26 公開日 2019-08-07 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Intracellular Trapping of the Selective Phosphoglycerate Dehydrogenase (PHGDH) InhibitorBI-4924Disrupts Serine Biosynthesis. J.Med.Chem., 62, 2019
6RL0	Recombinant Pseudomonas stutzeri nitrous oxide reductase, form I 分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, CHLORIDE ION, ... 著者 Zhang, L, Wuest, A, Prasser, B, Mueller, C, Einsle, O. 登録日 2019-04-30 公開日 2019-06-26 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Functional assembly of nitrous oxide reductase provides insights into copper site maturation. Proc.Natl.Acad.Sci.USA, 116, 2019
5HML	Crystal Structure of T5 D15 Protein Co-crystallized with Metal Ions 分子名称: 1,2-ETHANEDIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... 著者 Flemming, C.S, Feng, M, Sedelnikova, S.E, Zhang, J, Rafferty, J.B, Sayers, J.R, Artymiuk, P.J. 登録日 2016-01-16 公開日 2016-06-01 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.482 Å) 主引用文献 Direct observation of DNA threading in flap endonuclease complexes. Nat.Struct.Mol.Biol., 23, 2016
5KDW	IMPa metallopeptidase from Pseudomonas aeruginosa 分子名称: 1,2-ETHANEDIOL, Metallopeptidase, PHOSPHATE ION, ... 著者 Noach, I, Boraston, A.B. 登録日 2016-06-08 公開日 2017-01-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Recognition of protein-linked glycans as a determinant of peptidase activity. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6OXJ	X-ray crystal structure of Y140F FtmOx1 bound to Fe(II) 分子名称: FE (II) ION, Verruculogen synthase 著者 Dunham, N.P, Boal, A.K. 登録日 2019-05-13 公開日 2019-07-03 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Hydrogen Donation but not Abstraction by a Tyrosine (Y68) during Endoperoxide Installation by Verruculogen Synthase (FtmOx1). J.Am.Chem.Soc., 141, 2019
7SLC	[T:Ag+:T--pH 9] Metal-mediated DNA base pair in tensegrity triangle 分子名称: DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*TP*TP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*CP*CP*AP*TP*AP*CP*A)-3'), DNA (5'-D(P*CP*TP*GP*AP*TP*GP*T)-3'), ... 著者 Lu, B, Vecchioni, S, Seeman, N.C, Sha, R, Ohayon, Y.P. 登録日 2021-10-24 公開日 2022-10-26 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (4.02 Å) 主引用文献 Heterobimetallic Base Pair Programming in Designer 3D DNA Crystals. J.Am.Chem.Soc., 145, 2023
7SLM	[U:Ag+:U--pH 10] Metal-mediated DNA base pair in tensegrity triangle 分子名称: DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*UP*TP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*CP*CP*AP*UP*AP*CP*A)-3'), DNA (5'-D(P*CP*TP*GP*AP*TP*GP*T)-3'), ... 著者 Lu, B, Vecchioni, S, Seeman, N.C, Sha, R, Ohayon, Y.P. 登録日 2021-10-24 公開日 2022-10-26 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (4.3 Å) 主引用文献 Heterobimetallic Base Pair Programming in Designer 3D DNA Crystals. J.Am.Chem.Soc., 145, 2023
7SLO	[U:Ag+:U--pH 11] Metal-mediated DNA base pair in tensegrity triangle 分子名称: DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*UP*TP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*CP*CP*AP*UP*AP*CP*A)-3'), DNA (5'-D(P*CP*TP*GP*AP*TP*GP*T)-3'), ... 著者 Lu, B, Vecchioni, S, Seeman, N.C, Sha, R, Ohayon, Y.P. 登録日 2021-10-24 公開日 2022-10-26 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (4.12 Å) 主引用文献 Heterobimetallic Base Pair Programming in Designer 3D DNA Crystals. J.Am.Chem.Soc., 145, 2023
7NL6	Crystal Structure of DC-SIGN in complex with a triazole-based glycomimetic ligand 分子名称: CALCIUM ION, DC-SIGN, CRD domain, ... 著者 Jakob, R.P, Cramer, J, Lakkaichi, A, Aliu, B, Cattaneo, I, Klein, S, Jiang, X, Rabbani, S, Schwardt, O, Ernst, B, Maier, T. 登録日 2021-02-22 公開日 2021-10-27 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Sweet Drugs for Bad Bugs: A Glycomimetic Strategy against the DC-SIGN-Mediated Dissemination of SARS-CoV-2. J.Am.Chem.Soc., 143, 2021
7NL7	Crystal Structure of DC-SIGN in complex with a triazole-based glycomimetic ligand 分子名称: 3-Aminopropyl 2-deoxy-2-(4-phenyl-1,2,3-triazol-1-yl)-alpha-D-mannopyranoside, CALCIUM ION, DC-SIGN, ... 著者 Jakob, R.P, Cramer, J, Lakkaichi, A, Aliu, B, Cattaneo, I, Klein, S, Jiang, X, Rabbani, S, Schwardt, O, Ernst, B, Maier, T. 登録日 2021-02-22 公開日 2021-10-27 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Sweet Drugs for Bad Bugs: A Glycomimetic Strategy against the DC-SIGN-Mediated Dissemination of SARS-CoV-2. J.Am.Chem.Soc., 143, 2021
5ZWM	Cryo-EM structure of the yeast pre-B complex at an average resolution of 3.4~4.6 angstrom (tri-snRNP and U2 snRNP Part) 分子名称: 13 kDa ribonucleoprotein-associated protein, 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, Cold sensitive U2 snRNA suppressor 1, ... 著者 Bai, R, Wan, R, Yan, C, Lei, J, Shi, Y. 登録日 2018-05-16 公開日 2018-08-29 最終更新日 2019-11-06 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation Science, 360, 2018
7SLK	[U:Ag+:U--pH 9] Metal-mediated DNA base pair in tensegrity triangle 分子名称: DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*UP*TP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*CP*CP*AP*UP*AP*CP*A)-3'), DNA (5'-D(P*CP*TP*GP*AP*TP*GP*T)-3'), ... 著者 Lu, B, Vecchioni, S, Seeman, N.C, Sha, R, Ohayon, Y.P. 登録日 2021-10-24 公開日 2022-10-26 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (4.01 Å) 主引用文献 Heterobimetallic Base Pair Programming in Designer 3D DNA Crystals. J.Am.Chem.Soc., 145, 2023
6RSK	Cytochrome c co-crystallized with 20 eq. sulfonato-calix[8]arene and 15 eq. spermine - structure II 分子名称: Cytochrome c iso-1, HEME C, SPERMINE, ... 著者 Engilberge, S, Crowley, P.B. 登録日 2019-05-21 公開日 2019-09-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Tuning Protein Frameworks via Auxiliary Supramolecular Interactions. Acs Nano, 13, 2019
8EJ7	Polymorphism in SARS-CoV-2 Nsp5 main protease reveals differences in cleavage of viral and host substrates 分子名称: 3C-like proteinase nsp5 著者 Lu, J, Khan, M.B, Young, H.S, Lemieux, M.J. 登録日 2022-09-16 公開日 2023-05-03 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 SARS-CoV-2 M pro Protease Variants of Concern Display Altered Viral Substrate and Cell Host Target Galectin-8 Processing but Retain Sensitivity toward Antivirals. Acs Cent.Sci., 9, 2023
7PR5	Cocrystal of an RSL-N23H and sulfonato-thiacalix[4]arene - zinc complex 分子名称: Fucose-binding lectin protein, GLYCEROL, ZINC ION, ... 著者 Flood, R.J, Ramberg, K, Guagnini, F, Crowley, P.B. 登録日 2021-09-20 公開日 2022-03-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Protein Frameworks with Thiacalixarene and Zinc. Cryst.Growth Des., 22, 2022
7S08	Crystal structure of Epstein-Barr virus gH/gL targeting antibody 770F7 分子名称: 770F7 Fab Heavy chain, 770F7 Fab Light chain, GLYCEROL 著者 Chen, W.-H, Joyce, M.G. 登録日 2021-08-30 公開日 2022-11-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 Epstein-Barr virus gH/gL has multiple sites of vulnerability for virus neutralization and fusion inhibition. Immunity, 55, 2022
7PUK	Crystal structure of Endoglycosidase E GH18 domain from Enterococcus faecalis in complex with Man5 product 分子名称: Beta-N-acetylhexosaminidase, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Garcia-Alija, M, Du, J.J, Trastoy, B, Sundberg, E.J, Guerin, M. 登録日 2021-09-30 公開日 2022-03-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Mechanism of cooperative N-glycan processing by the multi-modular endoglycosidase EndoE. Nat Commun, 13, 2022
6ODA	Crystal structure of HDAC8 in complex with compound 2 分子名称: Histone deacetylase 8, N-{2-[3-(hydroxyamino)-3-oxopropyl]phenyl}-3-(trifluoromethyl)benzamide, POTASSIUM ION, ... 著者 Zheng, X, Conti, C, Caravella, J, Zablocki, M.-M, Bair, K, Barczak, N, Han, B, Lancia Jr, D, Liu, C, Martin, M, Ng, P.Y, Rudnitskaya, A, Thomason, J.J, Garcia-Dancey, R, Hardy, C, Lahdenranta, J, Leng, C, Li, P, Pardo, E, Saldahna, A, Tan, T, Toms, A.V, Yao, L, Zhang, C. 登録日 2019-03-26 公開日 2020-04-01 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.88 Å) 主引用文献 Structure-based Discovery of Novel N-(E)-N-Hydroxy-3-(2-(2-oxoimidazolidin-1-yl)phenyl)acrylamides as Potent and Selective HDAC8 inhibitors To Be Published
1AGZ	THE SOLUTION NMR STRUCTURE OF AN (R)-A-(N6-ADENYL)-STYRENE OXIDE-RAS61 OLIGODEOXYNUCLEOTIDE MODIFIED AT THE THIRD POSITION OF THE CODON 61 REGION, MINIMIZED AVERAGE STRUCTURE 分子名称: DNA (5'-D(*CP*GP*GP*AP*CP*AP*RP*GP*AP*AP*G)-3'), DNA (5'-D(*CP*TP*TP*CP*TP*TP*GP*TP*CP*CP*G)-3') 著者 Feng, B, Stone, M.P. 登録日 1997-03-26 公開日 1997-08-20 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Major groove (R)-alpha-(N6-adenyl)styrene oxide adducts in an oligodeoxynucleotide containing the human N-ras codon 61 sequence: conformations of the R(61,2) and R(61,3) sequence isomers from 1H NMR. Biochemistry, 34, 1995
6RIH	Crystal structure of PHGDH in complex with compound 9 分子名称: D-3-phosphoglycerate dehydrogenase, SULFATE ION, ~{N}-cyclopropyl-2-methyl-5-phenyl-pyrazole-3-carboxamide 著者 Bader, G, Wolkerstorfer, B, Zoephel, A. 登録日 2019-04-24 公開日 2019-08-07 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Intracellular Trapping of the Selective Phosphoglycerate Dehydrogenase (PHGDH) InhibitorBI-4924Disrupts Serine Biosynthesis. J.Med.Chem., 62, 2019

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