7PUK

Crystal structure of Endoglycosidase E GH18 domain from Enterococcus faecalis in complex with Man5 product

Summary for 7PUK

• Entry DOI: 10.2210/pdb7puk/pdb
• Descriptor: Beta-N-acetylhexosaminidase, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total)
• Functional Keywords: glycoside hydrolase, gh18, glycan, antibody, enterococcus faecalis, endoe, hydrolase
• Biological source: Enterococcus faecalis (Streptococcus faecalis)
• Total number of polymer chains: 2
• Total formula weight: 99988.50

Authors

Garcia-Alija, M.,Du, J.J.,Trastoy, B.,Sundberg, E.J.,Guerin, M. (deposition date: 2021-09-30, release date: 2022-03-16, Last modification date: 2024-01-31)

• Primary citation: Garcia-Alija, M.,Du, J.J.,Ordonez, I.,Diz-Vallenilla, A.,Moraleda-Montoya, A.,Sultana, N.,Huynh, C.G.,Li, C.,Donahue, T.C.,Wang, L.X.,Trastoy, B.,Sundberg, E.J.,Guerin, M.E.; Mechanism of cooperative N-glycan processing by the multi-modular endoglycosidase EndoE.; Nat Commun, 13:1137-1137, 2022; PubMed: 35241669; DOI: 10.1038/s41467-022-28722-w

Experimental method

X-RAY DIFFRACTION (2.69 Å)