7T3Q
| IP3 and ATP bound type 3 IP3 receptor in the pre-active B state | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate receptor type 3, ... | 著者 | Schmitz, E.A, Takahashi, H, Karakas, E. | 登録日 | 2021-12-08 | 公開日 | 2022-03-23 | 最終更新日 | 2022-05-04 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis for activation and gating of IP 3 receptors. Nat Commun, 13, 2022
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5IOM
| Crystal Structure of Nucleoside Diphosphate Kinase from Schistosoma mansoni is space group P6322 | 分子名称: | Nucleoside diphosphate kinase | 著者 | Torini, J.R.S, Romanello, L, Bird, L.E, Nettleship, J.E, Owens, R.J, Aller, P, DeMarco, R, Brandao-Neto, J, Pereira, H.M. | 登録日 | 2016-03-08 | 公開日 | 2017-08-09 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Characterization of a Schistosoma mansoni NDPK expressed in sexual and digestive organs. Mol.Biochem.Parasitol., 2019
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9CEJ
| Caulobacter crescentus FljJK flagellar filament (asymmetrical) | 分子名称: | Flagellin | 著者 | Sanchez, J.C, Montemayor, E.J, Ploscariu, N.T, Parrell, D, Baumgardt, J.K, Yang, J.E, Sibert, B, Cai, K, Wright, E.R. | 登録日 | 2024-06-26 | 公開日 | 2024-08-28 | 実験手法 | ELECTRON MICROSCOPY (2.53 Å) | 主引用文献 | Direct evidence for multi-flagellin filament stabilization via atomic-level architecture of Caulobacter crescentus flagellar filaments To Be Published
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8EMV
| Phospholipase C beta 3 (PLCb3) in solution | 分子名称: | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3, CALCIUM ION | 著者 | Falzone, M.E, MacKinnon, R. | 登録日 | 2022-09-28 | 公開日 | 2023-05-24 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | G beta gamma activates PIP2 hydrolysis by recruiting and orienting PLC beta on the membrane surface. Proc.Natl.Acad.Sci.USA, 120, 2023
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8OK4
| Variant Surface Glycoprotein VSG11wt-Oil | 分子名称: | Variant surface glycoprotein, alpha-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Zeelen, J.P, Stebbins, C.E, Aresta-Branco, F, Foti, K. | 登録日 | 2023-03-27 | 公開日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.23 Å) | 主引用文献 | A structural classification of the variant surface glycoproteins of the African trypanosomey. Plos Negl Trop Dis, 17, 2023
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9AX6
| Tricomplex of RMC-6236, KRAS G12D, and CypA | 分子名称: | (1R,2S)-N-[(1P,7S,9S,13R,20M)-21-ethyl-20-{2-[(1R)-1-methoxyethyl]-5-(4-methylpiperazin-1-yl)pyridin-3-yl}-17,17-dimethyl-8,14-dioxo-15-oxa-4-thia-9,21,27,28-tetraazapentacyclo[17.5.2.1~2,5~.1~9,13~.0~22,26~]octacosa-1(24),2,5(28),19,22,25-hexaen-7-yl]-2-methylcyclopropane-1-carboxamide, GTPase KRas, MAGNESIUM ION, ... | 著者 | Tomlinson, A.C.A, Saldajeno-Concar, M, Knox, J.E, Yano, J.K. | 登録日 | 2024-03-05 | 公開日 | 2024-04-17 | 最終更新日 | 2024-06-12 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Translational and Therapeutic Evaluation of RAS-GTP Inhibition by RMC-6236 in RAS-Driven Cancers. Cancer Discov, 14, 2024
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8OK8
| Variant Surface Glycoprotein VSG615 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Variant surface glycoprotein 615, ... | 著者 | Zeelen, J.P, Stebbins, C.E, Chandra, M. | 登録日 | 2023-03-27 | 公開日 | 2023-09-13 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (3.22 Å) | 主引用文献 | A structural classification of the variant surface glycoproteins of the African trypanosomey. Plos Negl Trop Dis, 17, 2023
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7T3T
| IP3, ATP, and Ca2+ bound type 3 IP3 receptor in the active state | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, ... | 著者 | Schmitz, E.A, Takahashi, H, Karakas, E. | 登録日 | 2021-12-08 | 公開日 | 2022-03-23 | 最終更新日 | 2022-05-04 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural basis for activation and gating of IP 3 receptors. Nat Commun, 13, 2022
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5I2Z
| Crystal structure of the catalytic domain of MMP-12 in complex with a selective sugar-conjugated triazole-linked carboxylate chelating water-soluble inhibitor (DC24). | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, DIMETHYL SULFOXIDE, ... | 著者 | Stura, E.A, Rosalia, L, Cuffaro, D, Tepshi, L, Ciccone, L, Rossello, A. | 登録日 | 2016-02-09 | 公開日 | 2016-07-06 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Sugar-Based Arylsulfonamide Carboxylates as Selective and Water-Soluble Matrix Metalloproteinase-12 Inhibitors. Chemmedchem, 11, 2016
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8OK5
| Variant Surface Glycoprotein VSG11 monomer with iodine | 分子名称: | IODIDE ION, Variant surface glycoprotein, alpha-D-glucopyranose, ... | 著者 | Zeelen, J.P, Stebbins, C.E, Aresta-Branco, F. | 登録日 | 2023-03-27 | 公開日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.27 Å) | 主引用文献 | A structural classification of the variant surface glycoproteins of the African trypanosomey. Plos Negl Trop Dis, 17, 2023
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7T3U
| IP3, ATP, and Ca2+ bound type 3 IP3 receptor in the inactive state | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, ... | 著者 | Schmitz, E.A, Takahashi, H, Karakas, E. | 登録日 | 2021-12-08 | 公開日 | 2022-03-23 | 最終更新日 | 2022-05-04 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural basis for activation and gating of IP 3 receptors. Nat Commun, 13, 2022
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8C6G
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6NAV
| Cryo-EM reconstruction of Sulfolobus islandicus LAL14/1 Pilus | 分子名称: | M9UD72 | 著者 | Wang, F, Cvirkaite-Krupovic, V, Prangishvili, D, Krupovic, M, Egelman, E.H. | 登録日 | 2018-12-06 | 公開日 | 2019-05-08 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | An extensively glycosylated archaeal pilus survives extreme conditions. Nat Microbiol, 4, 2019
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7T3R
| IP3 and ATP bound type 3 IP3 receptor in the pre-active C state | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate receptor type 3, ... | 著者 | Schmitz, E.A, Takahashi, H, Karakas, E. | 登録日 | 2021-12-08 | 公開日 | 2022-03-23 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural basis for activation and gating of IP 3 receptors. Nat Commun, 13, 2022
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6NX0
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8SUG
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7T4S
| CryoEM structure of the HCMV Pentamer gH/gL/UL128/UL130/UL131A in complex with NRP2 and neutralizing fabs 8I21 and 13H11 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Envelope glycoprotein H, ... | 著者 | Kschonsak, M, Johnson, M.C, Schelling, R, Green, E.M, Rouge, L, Ho, H, Patel, N, Kilic, C, Kraft, E, Arthur, C.P, Rohou, A.L, Comps-Agrar, L, Martinez-Martin, N, Perez, L, Payandeh, J, Ciferri, C. | 登録日 | 2021-12-10 | 公開日 | 2022-03-23 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis for HCMV Pentamer receptor recognition and antibody neutralization. Sci Adv, 8, 2022
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8A1A
| Structure of a leucinostatin derivative determined by host lattice display : L1F11V1 construct | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-(2-methoxyethoxy)-11,15-dimethyl-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one, ... | 著者 | Mittl, P.R.E. | 登録日 | 2022-06-01 | 公開日 | 2022-12-07 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structure of a hydrophobic leucinostatin derivative determined by host lattice display. Acta Crystallogr D Struct Biol, 78, 2022
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7T4Q
| CryoEM structure of the HCMV Pentamer gH/gL/UL128/UL130/UL131A in complex with neutralizing fabs 2C12, 7I13 and 13H11 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein H, Envelope glycoprotein L, ... | 著者 | Kschonsak, M, Johnson, M.C, Schelling, R, Green, E.M, Rouge, L, Ho, H, Patel, N, Kilic, C, Kraft, E, Arthur, C.P, Rohou, A.L, Comps-Agrar, L, Martinez-Martin, N, Perez, L, Payandeh, J, Ciferri, C. | 登録日 | 2021-12-10 | 公開日 | 2022-03-23 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural basis for HCMV Pentamer receptor recognition and antibody neutralization. Sci Adv, 8, 2022
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7T4R
| CryoEM structure of the HCMV Pentamer gH/gL/UL128/UL130/UL131A in complex with THBD and neutralizing fabs MSL-109 and 13H11 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein H, Envelope glycoprotein L, ... | 著者 | Kschonsak, M, Johnson, M.C, Schelling, R, Green, E.M, Rouge, L, Ho, H, Patel, N, Kilic, C, Kraft, E, Arthur, C.P, Rohou, A.L, Comps-Agrar, L, Martinez-Martin, N, Perez, L, Payandeh, J, Ciferri, C. | 登録日 | 2021-12-10 | 公開日 | 2022-03-23 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis for HCMV Pentamer receptor recognition and antibody neutralization. Sci Adv, 8, 2022
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8EMS
| Cryo-EM structure of human liver glycogen phosphorylase | 分子名称: | Glycogen phosphorylase, liver form, PYRIDOXAL-5'-PHOSPHATE | 著者 | Su, C, Lyu, M, Zhang, Z, Yu, E.W. | 登録日 | 2022-09-28 | 公開日 | 2023-05-10 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.65 Å) | 主引用文献 | High-resolution structural-omics of human liver enzymes. Cell Rep, 42, 2023
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8C68
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6NC4
| FtsY-NG high-resolution | 分子名称: | ACETATE ION, AMMONIUM ION, GLYCEROL, ... | 著者 | Ataide, S.F, Faoro, C. | 登録日 | 2018-12-10 | 公開日 | 2019-10-23 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural insights into the G-loop dynamics of E. coli FtsY NG domain. J.Struct.Biol., 208, 2019
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5L8C
| Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-039 | 分子名称: | 4-[5-[(4~{a}~{R},8~{a}~{S})-4-oxidanylidene-3-propan-2-yl-4~{a},5,8,8~{a}-tetrahydrophthalazin-1-yl]-2-methoxy-phenyl]-~{N}-(2-azanyl-2-oxidanylidene-ethyl)benzamide, DI(HYDROXYETHYL)ETHER, FORMIC ACID, ... | 著者 | Singh, A.K, Anthonyrajah, E.S, Brown, D.G. | 登録日 | 2016-06-07 | 公開日 | 2018-03-14 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Targeting a Subpocket in Trypanosoma brucei Phosphodiesterase B1 (TbrPDEB1) Enables the Structure-Based Discovery of Selective Inhibitors with Trypanocidal Activity. J. Med. Chem., 61, 2018
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8VJ0
| Neutron Structure of Oxidized Trp161Phe MnSOD | 分子名称: | MANGANESE (II) ION, Superoxide dismutase [Mn], mitochondrial | 著者 | Azadmanesh, J, Slobodnik, K, Struble, L.R, Lutz, W.E, Weiss, K.L, Myles, D.A.A, Kroll, T, Borgstahl, G.E.O. | 登録日 | 2024-01-05 | 公開日 | 2024-07-31 | 最終更新日 | 2024-10-16 | 実験手法 | NEUTRON DIFFRACTION (2.3 Å) | 主引用文献 | Revealing the atomic and electronic mechanism of human manganese superoxide dismutase product inhibition. Nat Commun, 15, 2024
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