7T4S

CryoEM structure of the HCMV Pentamer gH/gL/UL128/UL130/UL131A in complex with NRP2 and neutralizing fabs 8I21 and 13H11

Summary for 7T4S

Entry DOI	10.2210/pdb7t4s/pdb
EMDB information	25687
Descriptor	Envelope glycoprotein H, Fab 8I21 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (12 entities in total)
Functional Keywords	glycoprotein complex, antibody complex, neuropilin 2, viral protein, viral protein-immune system complex, viral protein/immune system
Biological source	Human betaherpesvirus 5 More
Total number of polymer chains	10
Total formula weight	387927.30
Authors	Kschonsak, M.,Johnson, M.C.,Schelling, R.,Green, E.M.,Rouge, L.,Ho, H.,Patel, N.,Kilic, C.,Kraft, E.,Arthur, C.P.,Rohou, A.L.,Comps-Agrar, L.,Martinez-Martin, N.,Perez, L.,Payandeh, J.,Ciferri, C. (deposition date: 2021-12-10, release date: 2022-03-23)
Primary citation	Kschonsak, M.,Johnson, M.C.,Schelling, R.,Green, E.M.,Rouge, L.,Ho, H.,Patel, N.,Kilic, C.,Kraft, E.,Arthur, C.P.,Rohou, A.L.,Comps-Agrar, L.,Martinez-Martin, N.,Perez, L.,Payandeh, J.,Ciferri, C. Structural basis for HCMV Pentamer receptor recognition and antibody neutralization. Sci Adv, 8:eabm2536-eabm2536, 2022 Cited by PubMed: 35275719 DOI: 10.1126/sciadv.abm2536 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.1 Å)

Structure validation