6ECV
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3NE5
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4M9J
| DNA Polymerase Beta E295K Soaked with dUMPNPP | 分子名称: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA Downstream Strand, ... | 著者 | Eckenroth, B.E, Doublie, S. | 登録日 | 2013-08-14 | 公開日 | 2013-10-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.038 Å) | 主引用文献 | The E295K Cancer Variant of Human Polymerase beta Favors the Mismatch Conformational Pathway during Nucleotide Selection. J.Biol.Chem., 288, 2013
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4M9Z
| Crystal structure of CED-4 bound CED-3 fragment | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CED-3 fragment, Cell death protein 4, ... | 著者 | Huang, W.J, Jinag, T.Y, Choi, W.Y, Wang, J.W, Shi, Y.G. | 登録日 | 2013-08-15 | 公開日 | 2013-10-23 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (3.405 Å) | 主引用文献 | Mechanistic insights into CED-4-mediated activation of CED-3. Genes Dev., 27, 2013
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5X8B
| Crystal structure of ATP-TMP and ADP bound thymidylate kinase from Thermus thermophilus HB8 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Chaudhary, S.K, Jeyakanthan, J, Sekar, K. | 登録日 | 2017-03-01 | 公開日 | 2018-03-14 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | 主引用文献 | Structural and functional roles of dynamically correlated residues in thymidylate kinase. Acta Crystallogr D Struct Biol, 74, 2018
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5XBR
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5X8V
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5X98
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6WYF
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4MHE
| Crystal structure of CC-chemokine 18 | 分子名称: | ACETATE ION, C-C motif chemokine 18 | 著者 | Liang, W.G, Tang, W.-J. | 登録日 | 2013-08-29 | 公開日 | 2014-09-03 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structures of human CCL18, CCL3, and CCL4 reveal molecular determinants for quaternary structures and sensitivity to insulin-degrading enzyme. J.Mol.Biol., 427, 2015
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6ELZ
| State E (TAP-Flag-Ytm1 E80A) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes | 分子名称: | 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 25S ribosomal RNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ... | 著者 | Kater, L, Cheng, J, Barrio-Garcia, C, Hurt, E, Beckmann, R. | 登録日 | 2017-09-30 | 公開日 | 2017-12-27 | 最終更新日 | 2024-10-23 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes. Cell, 171, 2017
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6EOC
| Crystal structure of AMPylated GRP78 in apo form (Crystal form 2) | 分子名称: | 78 kDa glucose-regulated protein, CITRATE ANION, SULFATE ION | 著者 | Yan, Y, Preissler, S, Ron, D, Read, R.J. | 登録日 | 2017-10-09 | 公開日 | 2017-11-01 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | AMPylation targets the rate-limiting step of BiP's ATPase cycle for its functional inactivation. Elife, 6, 2017
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4LQH
| High resolution structure of native frog M ferritin | 分子名称: | CHLORIDE ION, Ferritin, middle subunit, ... | 著者 | Mangani, S, Di Pisa, F, Pozzi, C, Turano, P, Lalli, D. | 登録日 | 2013-07-18 | 公開日 | 2014-07-23 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.16 Å) | 主引用文献 | Time-lapse anomalous X-ray diffraction shows how Fe(2+) substrate ions move through ferritin protein nanocages to oxidoreductase sites. Acta Crystallogr.,Sect.D, 71, 2015
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6EPD
| Substrate processing state 26S proteasome (SPS1) | 分子名称: | 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 13, ... | 著者 | Guo, Q, Lehmer, C, Martinez-Sanchez, A, Rudack, T, Beck, F, Hartmann, H, Hipp, M.S, Hartl, F.U, Edbauer, D, Baumeister, W, Fernandez-Busnadiego, R. | 登録日 | 2017-10-11 | 公開日 | 2018-02-07 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (15.4 Å) | 主引用文献 | In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment. Cell, 172, 2018
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3N9O
| ceKDM7A from C.elegans, complex with H3K4me3 peptide, H3K9me2 peptide and NOG | 分子名称: | FE (II) ION, Histone H3 peptide, N-OXALYLGLYCINE, ... | 著者 | Yang, Y, Hu, L, Wang, P, Hou, H, Chen, C.D, Xu, Y. | 登録日 | 2010-05-31 | 公開日 | 2010-06-30 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.309 Å) | 主引用文献 | Structural insights into a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans Cell Res., 20, 2010
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5XHU
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5XF1
| Structure of the Full-length glucagon class B G protein-coupled receptor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhang, H, Qiao, A, Yang, D, Yang, L, Dai, A, de Graaf, C, Reedtz-Runge, S, Dharmarajan, V, Zhang, H, Han, G.W, Grant, T, Sierra, R, Weierstall, U, Nelson, G, Liu, W, Wu, Y, Ma, L, Cai, X, Lin, G, Wu, X, Geng, Z, Dong, Y, Song, G, Griffin, P, Lau, J, Cherezov, V, Yang, H, Hanson, M, Stevens, R, Jiang, H, Wang, M, Zhao, Q, Wu, B. | 登録日 | 2017-04-06 | 公開日 | 2017-05-24 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.19 Å) | 主引用文献 | Structure of the full-length glucagon class B G-protein-coupled receptor. Nature, 546, 2017
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1KO8
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6ECT
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5XHN
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6EDT
| Mycobacterium tuberculosis RNAP open promoter complex with RbpA/CarD and AP3 promoter | 分子名称: | DNA (65-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J. | 登録日 | 2018-08-10 | 公開日 | 2018-11-21 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY | 主引用文献 | Structures of an RNA polymerase promoter melting intermediate elucidate DNA unwinding. Nature, 565, 2019
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6EF4
| Crystal structure of mouse PP2A Aalpha P179R mutant | 分子名称: | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform | 著者 | Wang, Z, Shen, G, Xu, W. | 登録日 | 2018-08-16 | 公開日 | 2019-06-26 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | The Highly Recurrent PP2A A alpha-Subunit Mutation P179R Alters Protein Structure and Impairs PP2A Enzyme Function to Promote Endometrial Tumorigenesis. Cancer Res., 79, 2019
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3NKA
| Crystal structure of AqpZ H174G,T183F | 分子名称: | Aquaporin Z, GLYCEROL, octyl beta-D-glucopyranoside | 著者 | Savage, D.F, O'Connell III, J.D, Finer-Moore, J, Stroud, R.M. | 登録日 | 2010-06-18 | 公開日 | 2010-11-03 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural context shapes the aquaporin selectivity filter. Proc.Natl.Acad.Sci.USA, 107, 2010
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5XGH
| Crystal structure of PI3K complex with an inhibitor | 分子名称: | 3-[(4-fluorophenyl)methylamino]-5-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phenol, GLYCEROL, Phosphatidylinositol 3-kinase regulatory subunit alpha, ... | 著者 | Song, K, Yang, X, Zhao, Y, Jian, Z. | 登録日 | 2017-04-13 | 公開日 | 2018-04-25 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.97 Å) | 主引用文献 | New Insights into PI3K Inhibitor Design using X-ray Structures of PI3K alpha Complexed with a Potent Lead Compound. Sci Rep, 7, 2017
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5XRG
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