3NKA

Crystal structure of AqpZ H174G,T183F

Summary for 3NKA

Related1RC2 3NK5 3NKC
DescriptorAquaporin Z, B-OCTYLGLUCOSIDE, GLYCEROL, ... (4 entities in total)
Functional Keywordsaquaporin, integral membrane protein, transport protein, selectivity filter mutants
Biological sourceEscherichia coli
Cellular locationCell inner membrane ; Multi- pass membrane protein  P60844
Total number of polymer chains2
Total molecular weight49403.64
Authors
Savage, D.F.,O'Connell III, J.D.,Finer-Moore, J.,Stroud, R.M. (deposition date: 2010-06-18, release date: 2010-11-03, Last modification date: 2017-11-08)
Primary citation
Savage, D.F.,O'Connell, J.D.,Miercke, L.J.,Finer-Moore, J.,Stroud, R.M.
Structural context shapes the aquaporin selectivity filter.
Proc.Natl.Acad.Sci.USA, 107:17164-17169, 2010
PubMed: 20855585 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1009864107
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.5 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.22030.4%3.7%5.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution