Crystal structure of AqpZ H174G,T183F

Summary for 3NKA

Related1RC2 3NK5 3NKC
DescriptorAquaporin Z, octyl beta-D-glucopyranoside, GLYCEROL, ... (4 entities in total)
Functional Keywordsaquaporin, integral membrane protein, transport protein, selectivity filter mutants
Biological sourceEscherichia coli
Total number of polymer chains2
Total molecular weight49403.64
Savage, D.F.,O'Connell III, J.D.,Finer-Moore, J.,Stroud, R.M. (deposition date: 2010-06-18, release date: 2010-11-03, Last modification date: 2020-07-29)
Primary citation
Savage, D.F.,O'Connell, J.D.,Miercke, L.J.,Finer-Moore, J.,Stroud, R.M.
Structural context shapes the aquaporin selectivity filter.
Proc.Natl.Acad.Sci.USA, 107:17164-17169, 2010
PubMed: 20855585 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1009864107
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2203 0.4% 3.7% 5.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-10-14