3NKA

Crystal structure of AqpZ H174G,T183F

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005886	cellular_component	plasma membrane
A	0006833	biological_process	water transport
A	0006970	biological_process	response to osmotic stress
A	0009992	biological_process	intracellular water homeostasis
A	0015250	molecular_function	water channel activity
A	0015267	molecular_function	channel activity
A	0016020	cellular_component	membrane
A	0042802	molecular_function	identical protein binding
A	0055085	biological_process	transmembrane transport
B	0005515	molecular_function	protein binding
B	0005886	cellular_component	plasma membrane
B	0006833	biological_process	water transport
B	0006970	biological_process	response to osmotic stress
B	0009992	biological_process	intracellular water homeostasis
B	0015250	molecular_function	water channel activity
B	0015267	molecular_function	channel activity
B	0016020	cellular_component	membrane
B	0042802	molecular_function	identical protein binding
B	0055085	biological_process	transmembrane transport

Functional Information from PROSITE/UniProt

site_id	PS00221
Number of Residues	9
Details	MIP MIP family signature. HFNPAVTIG

Chain	Residue	Details
A	HIS61-GLY69

---

site_id	PS00501
Number of Residues	8
Details	SPASE_I_1 Signal peptidases I serine active site. GYSMLSAL

Chain	Residue	Details
A	GLY128-LEU135

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	80
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	40
Details	Transmembrane: {"description":"Helical; Name=1","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	108
Details	Topological domain: {"description":"Periplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	40
Details	Transmembrane: {"description":"Helical; Name=2","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	40
Details	Transmembrane: {"description":"Helical; Name=3","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	40
Details	Transmembrane: {"description":"Helical; Name=4","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	40
Details	Transmembrane: {"description":"Helical; Name=5","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	40
Details	Transmembrane: {"description":"Helical; Name=6","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	4
Details	Motif: {"description":"NPA 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	4
Details	Motif: {"description":"NPA 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	2
Details	Site: {"description":"Involved in tetramerization or stability of the tetramer"}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	8
Details	Site: {"description":"Selectivity filter"}

Chain

Residue

Details

---