PDB: 274 件ウェブページステータス検索Chemie searchBIRD

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3EYB	Structural and functional insights into the ligand binding domain of a non-duplicated RXR from the invertebrate chordate amphioxus 分子名称: Nuclear hormone receptor RXR 著者 Tocchini-Valentini, G.D, Rochel, N, Moras, D, Structural Proteomics in Europe (SPINE) 登録日 2008-10-20 公開日 2008-11-04 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Structural and functional insights into the ligand-binding domain of a nonduplicated retinoid X nuclear receptor from the invertebrate chordate amphioxus J.Biol.Chem., 284, 2009
6H4J	Usp25 catalytic domain 分子名称: CHLORIDE ION, Ubiquitin carboxyl-terminal hydrolase 25 著者 Klemm, T.A, Sauer, F, Kisker, C. 登録日 2018-07-21 公開日 2019-03-27 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.07 Å) 主引用文献 Differential Oligomerization of the Deubiquitinases USP25 and USP28 Regulates Their Activities. Mol.Cell, 74, 2019
2MUU	The Proteolytic Activity of Ubiquitin-specific Protease 28 Is Modulated by the N-terminal Domain 分子名称: Ubiquitin carboxyl-terminal hydrolase 28 著者 Wen, Y, Shi, L, Zhang, N. 登録日 2014-09-17 公開日 2016-04-20 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 The N-terminal ubiquitin-binding region of ubiquitin-specific protease 28 modulates its deubiquitination function: NMR structural and mechanistic insights. Biochem.J., 471, 2015
6ML1	Structure of the USP15 deubiquitinase domain in complex with an affinity-matured inhibitory Ubv 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... 著者 Singer, A.U, Teyra, J, Boehmelt, G, Lenter, M, Sicheri, F, Sidhu, S.S. 登録日 2018-09-26 公開日 2019-01-23 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural and Functional Characterization of Ubiquitin Variant Inhibitors of USP15. Structure, 27, 2019
1R0N	Crystal Structure of Heterodimeric Ecdsyone receptor DNA binding complex 分子名称: Ecdsyone Response Element, Ecdysone Response Element, Ecdysone receptor, ... 著者 Devarakonda, S, Harp, J.M, Kim, Y, Ozyhar, A, Rastinejad, F. 登録日 2003-09-22 公開日 2003-10-21 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of the heterodimeric Ecdysone Receptor DNA-binding complex Embo J., 22, 2003
5XU8	Crystal structure of human USP2 in complex with ubiquitin and 6-thioguanine 分子名称: 2-amino-1,9-dihydro-6H-purine-6-thione, CHLORIDE ION, SODIUM ION, ... 著者 Chou, C.Y, Chuang, S.J. 登録日 2017-06-22 公開日 2018-02-28 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 6-Thioguanine is a noncompetitive and slow binding inhibitor of human deubiquitinating protease USP2 Sci Rep, 8, 2018
8XPN	The Crystal Structure of USP8 from Biortus. 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Ubiquitin carboxyl-terminal hydrolase 8, ... 著者 Wang, F, Cheng, W, Yuan, Z, Lin, D, Wang, J. 登録日 2024-01-04 公開日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The Crystal Structure of USP8 from Biortus. To Be Published
7YXX	Cryo-EM structure of USP9X 分子名称: Probable ubiquitin carboxyl-terminal hydrolase FAF-X 著者 Deme, J.C, Halabelian, L, Arrowsmith, C.H, Lea, S.M, Structural Genomics Consortium (SGC) 登録日 2022-02-16 公開日 2022-03-02 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Cryo-EM structure of USP9X To Be Published
7YXY	Cryo-EM structure of USP9X, local refinement of monomer 分子名称: Probable ubiquitin carboxyl-terminal hydrolase FAF-X 著者 Deme, J.C, Halabelian, L, Arrowsmith, C.H, Lea, S.M, Structural Genomics Consortium (SGC) 登録日 2022-02-16 公開日 2022-03-02 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Cryo-EM structure of USP9X To Be Published
4WA6	Structure of yeast SAGA DUBm with Sgf73 N59D mutant at 2.36 angstroms resolution 分子名称: SAGA-associated factor 11, SAGA-associated factor 73, Transcription and mRNA export factor SUS1, ... 著者 Wolberger, C, Yan, M. 登録日 2014-08-28 公開日 2015-03-04 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Structure of yeast SAGA DUBm with Sgf73 N59D mutant at 2.36 angstroms resolution To Be Published
7TUO	Crystal structure analysis of human USP28 complex with a compound 分子名称: 7-amino-N-(2-{4-[(1R,3s,5S)-8-azabicyclo[3.2.1]octan-3-yl]phenyl}ethyl)-3-methylthieno[2,3-b]pyrazine-6-carboxamide, CHLORIDE ION, Ubiquitin carboxyl-terminal hydrolase 28 著者 Seo, H.-S, Dhe-Paganon, S. 登録日 2022-02-03 公開日 2023-02-15 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Crystal Structure Analysis of human USP28 complex with a compound To Be Published
6T9L	SAGA DUB module bound to a ubiqitinated nucleosome 分子名称: Histone H2A, Histone H2B, Histone H2B 1.1, ... 著者 Wang, H, Cramer, P. 登録日 2019-10-28 公開日 2020-01-29 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structure of the transcription coactivator SAGA. Nature, 577, 2020
6TBM	Structure of SAGA bound to TBP, including Spt8 and DUB 分子名称: Polyubiquitin-B, SAGA-associated factor 11, Spt20, ... 著者 Papai, G, Frechard, A, Kolesnikova, O, Crucifix, C, Schultz, P, Ben-Shem, A. 登録日 2019-11-01 公開日 2020-02-12 最終更新日 2021-06-30 実験手法 ELECTRON MICROSCOPY (20 Å) 主引用文献 Structure of SAGA and mechanism of TBP deposition on gene promoters. Nature, 577, 2020
1VJV	Crystal structure of Ubiquitin carboxyl-terminal hydrolase 6 (yfr010w) from Saccharomyces cerevisiae at 1.74 A resolution 分子名称: Ubiquitin carboxyl-terminal hydrolase 6 著者 Joint Center for Structural Genomics (JCSG) 登録日 2004-03-29 公開日 2004-09-21 最終更新日 2023-01-25 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Crystal structure of Ubiquitin carboxyl-terminal hydrolase 6 (yfr010w) from Saccharomyces cerevisiae at 1.74 A resolution To be published
5FWI	structure of usp7 catalytic domain and three ubl-domains 分子名称: UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7 著者 Kim, R.Q, van Dijk, W.J, Sixma, T.K. 登録日 2016-02-17 公開日 2016-06-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Structure of Usp7 Catalytic Domain and Three Ubl-Domains Reveals a Connector Alpha-Helix with Regulatory Role. J.Struct.Biol., 195, 2016
2Y6E	Structure of the D1D2 domain of USP4, the conserved catalytic domain 分子名称: SULFATE ION, UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 4, ZINC ION 著者 Luna-Vargas, M.P.A, Faesen, A.C, van Dijk, W.J, Rape, M, Fish, A, Sixma, T.K. 登録日 2011-01-20 公開日 2011-04-06 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The Dusp-Ubl Domain of Usp4 Enhances its Catalytic Efficiency by Promoting Ubiquitin Exchange. Nat.Commun., 5, 2014
6M1K	USP7 in complex with a novel inhibitor 分子名称: Ubiquitin carboxyl-terminal hydrolase 7, methyl 4-[[4-[[3-[4-(aminomethyl)phenyl]-2-methyl-7-oxidanylidene-pyrazolo[4,3-d]pyrimidin-6-yl]methyl]-4-oxidanyl-piperidin-1-yl]methyl]-3-chloranyl-benzoate 著者 Liu, S.J, Zhou, X.Y, Li, M.L, Sun, H.B, Wen, X.A. 登録日 2020-02-26 公開日 2021-03-10 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.255 Å) 主引用文献 N-benzylpiperidinol derivatives as novel USP7 inhibitors: Structure-activity relationships and X-ray crystallographic studies. Eur.J.Med.Chem., 199, 2020
6CPM	Structure of the USP15 deubiquitinase domain in complex with a third-generation inhibitory Ubv 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, GLYCEROL, ... 著者 Singer, A.U, Teyra, J, Boehmelt, G, Lenter, M, Sicheri, F, Sidhu, S.S. 登録日 2018-03-13 公開日 2019-01-23 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.011 Å) 主引用文献 Structural and Functional Characterization of Ubiquitin Variant Inhibitors of USP15. Structure, 27, 2019
6CRN	Structure of the USP15 deubiquitinase domain in complex with a high-affinity first-generation Ubv 分子名称: Ubiquitin carboxyl-terminal hydrolase 15, Ubiquitin variant 15.2, ZINC ION 著者 Singer, A.U, Teyra, J, Boehmelt, G, Lenter, M, Sicheri, F, Sidhu, S.S. 登録日 2018-03-19 公開日 2019-01-23 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural and Functional Characterization of Ubiquitin Variant Inhibitors of USP15. Structure, 27, 2019
4R2L	Crystal structure of YnaF (Universal Stress Protein F) from Salmonella typhimurium 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ... 著者 Bangera, M, Murthy, M.R.N. 登録日 2014-08-12 公開日 2015-02-04 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural and functional analysis of two universal stress proteins YdaA and YnaF from Salmonella typhimurium: possible roles in microbial stress tolerance. J.Struct.Biol., 189, 2015
4R2M	Crystal Structure of R134D mutant of YnaF (Universal Stress Protein F) from Salmonella typhimurium 分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Universal stress protein F 著者 Bangera, M, Murthy, M.R.N. 登録日 2014-08-12 公開日 2015-02-04 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural and functional analysis of two universal stress proteins YdaA and YnaF from Salmonella typhimurium: possible roles in microbial stress tolerance. J.Struct.Biol., 189, 2015
8WG5	Cryo-EM structure of USP16 bound to H2AK119Ub nucleosome 分子名称: DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ... 著者 Ai, H.S, He, Z.Z, Deng, Z.H, Liu, L. 登録日 2023-09-20 公開日 2023-12-27 実験手法 ELECTRON MICROSCOPY (3.05 Å) 主引用文献 Cryo-EM structure of USP16 bound to H2AK119Ub nucleosome To Be Published
6F5H	Crystal structure of USP7 in complex with a 4-hydroxypiperidine based inhibitor 分子名称: 3-[[4-oxidanyl-1-[(3~{R})-3-phenylbutanoyl]piperidin-4-yl]methyl]-6-(2-pyrrolidin-1-ylethylamino)pyrimidin-4-one, GLYCEROL, SULFATE ION, ... 著者 Harrison, T, Gavory, G, O'Dowd, C, Helm, M, Flasz, J, Dossang, A, Hughes, C, Cassidy, E, McClelland, K, Odrzywol, E, Page, N, Barker, O, Miel, H, Feutron-Burton, S, Rountree, J.S.S. 登録日 2017-12-01 公開日 2018-04-11 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.16 Å) 主引用文献 Identification and Structure-Guided Development of Pyrimidinone Based USP7 Inhibitors. ACS Med Chem Lett, 9, 2018
4M5W	Crystal structure of the USP7/HAUSP catalytic domain 分子名称: BROMIDE ION, Ubiquitin carboxyl-terminal hydrolase 7 著者 Molland, K.L, Mesecar, A.D, Zhou, Q. 登録日 2013-08-08 公開日 2014-03-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.244 Å) 主引用文献 A 2.2 angstrom resolution structure of the USP7 catalytic domain in a new space group elaborates upon structural rearrangements resulting from ubiquitin binding. Acta Crystallogr F Struct Biol Commun, 70, 2014
5GJQ	Structure of the human 26S proteasome bound to USP14-UbAl 分子名称: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ... 著者 Huang, X.L, Luan, B, Wu, J.P, Shi, Y.G. 登録日 2016-07-01 公開日 2016-08-17 最終更新日 2019-11-06 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 An atomic structure of the human 26S proteasome. Nat. Struct. Mol. Biol., 23, 2016

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