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5JHL
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Crystal structure of zika virus envelope protein in complex with a flavivirus broadly-protective antibody
分子名称: Antibody Heavy chain, antibody Light chain, envelope protein
著者Dai, L, Shi, Y, Qi, J, Gao, G.F.
登録日2016-04-21
公開日2016-05-11
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structures of the Zika Virus Envelope Protein and Its Complex with a Flavivirus Broadly Protective Antibody.
Cell Host Microbe, 19, 2016
3SKJ
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BU of 3skj by Molmil
Structural And Functional Characterization of an Agonistic Anti-Human EphA2 Monoclonal Antibody
分子名称: Antibody, heavy chain, light chain, ...
著者Oganesyan, V.Y, Wu, H, Dall'Acqua, W.F.
登録日2011-06-22
公開日2011-08-31
最終更新日2017-05-31
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and functional characterization of an agonistic anti-human EphA2 monoclonal antibody.
J.Mol.Biol., 413, 2011
3VW3
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BU of 3vw3 by Molmil
Antibody 64M-5 Fab in complex with a double-stranded DNA (6-4) photoproduct
分子名称: Anti-(6-4) photoproduct antibody 64M-5 Fab (heavy chain), Anti-(6-4) photoproduct antibody 64M-5 Fab (light chain), COBALT HEXAMMINE(III), ...
著者Yokoyama, H, Mizutani, R, Satow, Y.
登録日2012-07-30
公開日2013-03-27
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of a double-stranded DNA (6-4) photoproduct in complex with the 64M-5 antibody Fab
Acta Crystallogr.,Sect.D, 69, 2013
6H5N
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Plasmodium falciparum Pfs48/45 C-terminal domain bound to monoclonal antibody 85RF45.1
分子名称: Antibody 85RF45.1 heavy chain, Antibody 85RF45.1 light chain, Gametocyte surface protein P45/48
著者Lennartz, F, Higgins, M.K.
登録日2018-07-25
公開日2018-09-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.23 Å)
主引用文献Structural basis for recognition of the malaria vaccine candidate Pfs48/45 by a transmission blocking antibody.
Nat Commun, 9, 2018
1G6V
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Complex of the camelid heavy-chain antibody fragment CAB-CA05 with bovine carbonic anhydrase
分子名称: ANTIBODY HEAVY CHAIN, CARBONIC ANHYDRASE, ZINC ION
著者Desmyter, A, Decanniere, K, Muyldermans, S, Wyns, L.
登録日2000-11-08
公開日2000-11-22
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Antigen specificity and high affinity binding provided by one single loop of a camel single-domain antibody.
J.Biol.Chem., 276, 2001
1D6V
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CONFORMATION EFFECTS IN BIOLOGICAL CATALYSIS INTRODUCED BY OXY-COPE ANTIBODY MATURATION
分子名称: (1S,2S,5S)2-(4-GLUTARIDYLBENZYL)-5-PHENYL-1-CYCLOHEXANOL, CADMIUM ION, CHIMERIC GERMLINE PRECURSOR OF OXY-COPE CATALYTIC ANTIBODY AZ-28 (HEAVY CHAIN), ...
著者Mundorff, E.C, Hanson, M.A, Schultz, P.G, Stevens, R.C.
登録日1999-10-15
公開日2000-02-09
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Conformational effects in biological catalysis: an antibody-catalyzed oxy-cope rearrangement.
Biochemistry, 39, 2000
3VG0
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Antibody Fab fragment
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, Monoclonal antibody 9F8 Fab fragment H chain, ...
著者Carpenter, B, Hemsworth, G.R, Ross, R.J, Artymiuk, P.J.
登録日2012-01-10
公開日2012-03-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Structure of the human obesity receptor leptin-binding domain reveals the mechanism of leptin antagonism by a monoclonal antibody.
Structure, 20, 2012
6U85
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Site-specific lysine arylation as an alternative bioconjugation strategy for chemically programmed antibodies and antibody-drug conjugates
分子名称: Antibody Fab heavy chain, GLYCEROL, antibody Fab Light chain
著者Park, H, Rader, C.
登録日2019-09-04
公開日2019-11-13
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Site-Specific Lysine Arylation as an Alternative Bioconjugation Strategy for Chemically Programmed Antibodies and Antibody-Drug Conjugates.
Bioconjug.Chem., 30, 2019
5F96
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Crystal structure of broadly neutralizing VH1-46 germline-derived CD4-binding site-directed antibody CH235.12 in complex with HIV-1 clade A/E 93TH057 gp120
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HEAVY CHAIN OF ANTIBODY CH235.12, ...
著者Zhou, T, Kwong, P.D.
登録日2015-12-09
公開日2016-03-09
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.2407 Å)
主引用文献Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody.
Cell, 165, 2016
5F9W
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Crystal structure of broadly neutralizing VH1-46 germline-derived CD4-binding site-directed antibody CH235 in complex with HIV-1 clade A/E 93TH057 gp120
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of CH235-lineage antibody CH235, Light chain of CH235-lineage antibody CH235, ...
著者Chen, L, Zhou, T, Kwong, P.D.
登録日2015-12-10
公開日2016-03-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.8911 Å)
主引用文献Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody.
Cell, 165, 2016
1G7H
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CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3(VLW92A)
分子名称: ANTI-HEN EGG WHITE LYSOZYME MONOCLONAL ANTIBODY D1.3, LYSOZYME C
著者Sundberg, E.J, Urrutia, M, Braden, B.C, Isern, J, Mariuzza, R.A.
登録日2000-11-10
公開日2000-11-22
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface.
Biochemistry, 39, 2000
1G7J
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CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3 (VLW92H)
分子名称: ANTI-HEN EGG WHITE LYSOZYME MONOCLONAL ANTIBODY D1.3, LYSOZYME C
著者Sundberg, E.J, Urrutia, M, Braden, B.C, Isern, J, Mariuzza, R.A.
登録日2000-11-10
公開日2000-11-22
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface.
Biochemistry, 39, 2000
1FL5
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THE UNLIGANDED GERMLINE PRECURSOR TO THE SULFIDE OXIDASE CATALYTIC ANTIBODY 28B4.
分子名称: ANTIBODY GERMLINE PRECURSOR TO ANTIBODY 28B4, SULFATE ION
著者Yin, J, Mundorff, E.C, Yang, P.L, Wendt, K.U, Hanway, D, Stevens, R.C, Schultz, P.G.
登録日2000-08-11
公開日2001-11-14
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A comparative analysis of the immunological evolution of antibody 28B4.
Biochemistry, 40, 2001
4NIK
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BU of 4nik by Molmil
Structure of human Gankyrin in complex to the single chain antibody F5
分子名称: 26S proteasome non-ATPase regulatory subunit 10, Single-chain Fv fragment antibody
著者Sato, Y, Weiss, E, Rochel, N.
登録日2013-11-06
公開日2014-09-10
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Restricted diversity of antigen binding residues of antibodies revealed by computational alanine scanning of 227 antibody-antigen complexes
J.Mol.Biol., 426, 2014
1A4K
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BU of 1a4k by Molmil
DIELS ALDER CATALYTIC ANTIBODY WITH TRANSITION STATE ANALOGUE
分子名称: ANTIBODY FAB, CADMIUM ION, [4-(4-ACETYLAMINO-PHENYL)-3,5-DIOXO-4-AZA-TRICYCLO[5.2.2.0 2,6]UNDEC-1-YLCARBAMOYLOXY]-ACETIC ACID
著者Spiller, B.W, Romesburg, F.E, Schultz, P.G, Stevens, R.C.
登録日1998-01-30
公開日1998-05-13
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Immunological origins of binding and catalysis in a Diels-Alderase antibody.
Science, 279, 1998
5F3H
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Structure of myostatin in complex with humanized RK35 antibody
分子名称: Growth/differentiation factor 8, humanized RK35 antibody heavy chain, humanized RK35 antibody light chain
著者Parris, K.D, Mosyak, L.
登録日2015-12-02
公開日2016-09-28
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Beyond CDR-grafting: Structure-guided humanization of framework and CDR regions of an anti-myostatin antibody.
Mabs, 8, 2016
1G7M
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CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3 (VLW92V)
分子名称: ANTI-HEN EGG WHITE LYSOZYME MONOCLONAL ANTIBODY D1.3, LYSOZYME C
著者Sundberg, E.J, Urrutia, M, Braden, B.C, Isern, J, Mariuzza, R.A.
登録日2000-11-10
公開日2000-11-22
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface.
Biochemistry, 39, 2000
1G7L
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CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3 (VLW92S)
分子名称: ANTI-HEN EGG WHITE LYSOZYME MONOCLONAL ANTIBODY D1.3, LYSOZYME C
著者Sundberg, E.J, Urrutia, M, Braden, B.C, Isern, J, Mariuzza, R.A.
登録日2000-11-10
公開日2000-11-22
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface.
Biochemistry, 39, 2000
5F3B
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Structure of myostatin in complex with chimeric RK35 antibody
分子名称: GLYCEROL, Growth/differentiation factor 8, RK35 Chimeric antibody heavy chain, ...
著者Parris, K.D, Mosyak, L.
登録日2015-12-02
公開日2016-09-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Beyond CDR-grafting: Structure-guided humanization of framework and CDR regions of an anti-myostatin antibody.
Mabs, 8, 2016
1G7I
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CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3 (VLW92F)
分子名称: ANTI-HEN EGG WHITE LYSOZYME MONOCLONAL ANTIBODY D1.3, LYSOZYME C, PHOSPHATE ION
著者Sundberg, E.J, Urrutia, M, Braden, B.C, Isern, J, Mariuzza, R.A.
登録日2000-11-10
公開日2000-11-22
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface.
Biochemistry, 39, 2000
3ESU
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BU of 3esu by Molmil
Crystal structure of anthrax-neutralizing single-chain antibody 14b7
分子名称: Antibody 14b7* light chain and antibody 14b7* heavy chain linked with a synthetic (GGGGS)4 linker
著者Monzingo, A.F, Maynard, J.A, Iverson, B.L, Georgiou, G, Robertus, J.D.
登録日2008-10-06
公開日2009-04-28
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Crystal structure of the engineered neutralizing antibody m18 complexed to domain 4 of the anthrax protective antigen.
J.Mol.Biol., 387, 2009
5W4L
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Crystal structure of the non-neutralizing and ADCC-potent C11-like antibody N12-i3 in complex with HIV-1 clade A/E gp120, the CD4 mimetic M48U1, and the antibody N5-i5.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody N12-i3 Fab heavy chain, Antibody N12-i3 light chain, ...
著者Tolbert, W.D, Gohain, N, Pazgier, M.
登録日2017-06-12
公開日2017-11-15
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.92 Å)
主引用文献Targeting the Late Stage of HIV-1 Entry for Antibody-Dependent Cellular Cytotoxicity: Structural Basis for Env Epitopes in the C11 Region.
Structure, 25, 2017
6A0X
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Crystal structure of broadly neutralizing antibody 13D4
分子名称: Antibody 13D4, Fab Heavy Chain, Fab Light Chain
著者Li, S, Li, T.
登録日2018-06-06
公開日2018-06-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Basis for the Broad, Antibody-Mediated Neutralization of H5N1 Influenza Virus.
J. Virol., 92, 2018
7KQ7
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Crystal structure of IL21R in complex with an antibody Fab fragment
分子名称: Antibody heavy chain, Antibody light chain, Interleukin-21 receptor
著者Mosyak, L, Svenson, K.
登録日2020-11-13
公開日2021-04-07
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.203 Å)
主引用文献Combining random mutagenesis, structure-guided design and next-generation sequencing to mitigate polyreactivity of an anti-IL-21R antibody.
Mabs, 13, 2021
1AXS
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MATURE OXY-COPE CATALYTIC ANTIBODY WITH HAPTEN
分子名称: (1S,2S,5S)2-(4-GLUTARIDYLBENZYL)-5-PHENYL-1-CYCLOHEXANOL, CADMIUM ION, OXY-COPE CATALYTIC ANTIBODY
著者Mundorff, E.C, Ulrich, H.D, Stevens, R.C.
登録日1997-10-20
公開日1998-02-04
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The interplay between binding energy and catalysis in the evolution of a catalytic antibody.
Nature, 389, 1997

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