6H5N

Plasmodium falciparum Pfs48/45 C-terminal domain bound to monoclonal antibody 85RF45.1

Summary for 6H5N

Entry DOI	10.2210/pdb6h5n/pdb
Descriptor	Gametocyte surface protein P45/48, Antibody 85RF45.1 light chain, Antibody 85RF45.1 heavy chain (3 entities in total)
Functional Keywords	pfs48/45 gamete fusion plasmodium falciparum transmission blocking monoclonal antibody, cell invasion
Biological source	Plasmodium falciparum (isolate 3D7) More
Total number of polymer chains	6
Total formula weight	124270.55
Authors	Lennartz, F.,Higgins, M.K. (deposition date: 2018-07-25, release date: 2018-09-26, Last modification date: 2024-01-17)
Primary citation	Lennartz, F.,Brod, F.,Dabbs, R.,Miura, K.,Mekhaiel, D.,Marini, A.,Jore, M.M.,Sogaard, M.M.,Jorgensen, T.,de Jongh, W.A.,Sauerwein, R.W.,Long, C.A.,Biswas, S.,Higgins, M.K. Structural basis for recognition of the malaria vaccine candidate Pfs48/45 by a transmission blocking antibody. Nat Commun, 9:3822-3822, 2018 Cited by PubMed: 30237518 DOI: 10.1038/s41467-018-06340-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.23 Å)

Structure validation