7EH0
 
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7EH2
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7EH1
 | | Thermus thermophilus transcription initiation complex containing a template-strand purine at position TSS-2, GpG RNA primer, and CMPcPP | | 分子名称: | 1,4-BUTANEDIOL, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (27-MER), ... | | 著者 | Li, L, Zhang, Y. | | 登録日 | 2021-03-27 | | 公開日 | 2021-07-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Promoter-sequence determinants and structural basis of primer-dependent transcription initiation in Escherichia coli .
Proc.Natl.Acad.Sci.USA, 118, 2021
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7LQ4
 | | Rr (RsiG)2-(c-di-GMP)2-WhiG complex | | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), RsiG, WhiG | | 著者 | Schumacher, M.A, Brennan, R.G. | | 登録日 | 2021-02-12 | | 公開日 | 2021-07-14 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Evolution of a sigma-(c-di-GMP)-anti-sigma switch.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7KIF
 | | Mycobacterium tuberculosis WT RNAP transcription open promoter complex with WhiB7 transcription factor | | 分子名称: | DNA (55-MER), DNA (63-MER), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Lilic, M, Darst, S.A, Campbell, E.A. | | 登録日 | 2020-10-23 | | 公開日 | 2021-04-21 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (2.94 Å) | | 主引用文献 | Structural basis of transcriptional activation by the Mycobacterium tuberculosis intrinsic antibiotic-resistance transcription factor WhiB7.
Mol.Cell, 81, 2021
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7KIM
 | | Mycobacterium tuberculosis WT RNAP transcription closed promoter complex with WhiB7 transcription factor | | 分子名称: | DNA (45-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Lilic, M, Darst, S.A, Campbell, E.A. | | 登録日 | 2020-10-23 | | 公開日 | 2021-04-21 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | | 主引用文献 | Structural basis of transcriptional activation by the Mycobacterium tuberculosis intrinsic antibiotic-resistance transcription factor WhiB7.
Mol.Cell, 81, 2021
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7KIN
 | | Mycobacterium tuberculosis WT RNAP transcription open promoter complex with WhiB7 promoter | | 分子名称: | DNA (49-MER), DNA (54-MER), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Lilic, M, Darst, S.A, Campbell, E.A. | | 登録日 | 2020-10-23 | | 公開日 | 2021-04-21 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (2.74 Å) | | 主引用文献 | Structural basis of transcriptional activation by the Mycobacterium tuberculosis intrinsic antibiotic-resistance transcription factor WhiB7.
Mol.Cell, 81, 2021
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6XH7
 | | CueR-TAC without RNA | | 分子名称: | COPPER (II) ION, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Liu, B, Shi, W, Yang, Y. | | 登録日 | 2020-06-18 | | 公開日 | 2021-04-14 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structural basis of copper-efflux-regulator-dependent transcription activation.
Iscience, 24, 2021
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6XH8
 | | CueR-transcription activation complex with RNA transcript | | 分子名称: | COPPER (II) ION, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Liu, B, Shi, W, Yang, Y. | | 登録日 | 2020-06-18 | | 公開日 | 2021-04-14 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structural basis of copper-efflux-regulator-dependent transcription activation.
Iscience, 24, 2021
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6XL9
 | | Cryo-EM structure of EcmrR-RNAP-promoter initial transcribing complex with 3-nt RNA transcript (EcmrR-RPitc-3nt) | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Yang, Y, Liu, C, Shi, W, Liu, B. | | 登録日 | 2020-06-28 | | 公開日 | 2021-04-07 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Structural visualization of transcription activated by a multidrug-sensing MerR family regulator.
Nat Commun, 12, 2021
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6XLJ
 | | Cryo-EM structure of EcmrR-RNAP-promoter initial transcribing complex with 4-nt RNA transcript (EcmrR-RPitc-4nt) | | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Yang, Y, Liu, C, Liu, B. | | 登録日 | 2020-06-28 | | 公開日 | 2021-04-07 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structural visualization of transcription activated by a multidrug-sensing MerR family regulator.
Nat Commun, 12, 2021
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6XL5
 | | Cryo-EM structure of EcmrR-RNAP-promoter open complex (EcmrR-RPo) | | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Yang, Y, Liu, C, Liu, B. | | 登録日 | 2020-06-28 | | 公開日 | 2021-04-07 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Structural visualization of transcription activated by a multidrug-sensing MerR family regulator.
Nat Commun, 12, 2021
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6XLM
 | | Cryo-EM structure of E.coli RNAP-DNA elongation complex 1 (RDe1) in EcmrR-dependent transcription | | 分子名称: | 9-nt RNA transcript, CHAPSO, DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Yang, Y, Liu, C, Liu, B. | | 登録日 | 2020-06-28 | | 公開日 | 2021-04-07 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural visualization of transcription activated by a multidrug-sensing MerR family regulator.
Nat Commun, 12, 2021
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6XLL
 | | Cryo-EM structure of E. coli RNAP-promoter initial transcribing complex with 5-nt RNA transcript (RPitc-5nt) | | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Yang, Y, Liu, C, Liu, B. | | 登録日 | 2020-06-28 | | 公開日 | 2021-04-07 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structural visualization of transcription activated by a multidrug-sensing MerR family regulator.
Nat Commun, 12, 2021
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7CKQ
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7KHE
 | | Escherichia coli RNA polymerase and rrnBP1 promoter pre-open complex with DksA/ppGpp | | 分子名称: | CHAPSO, DNA (46-MER), DNA (54-MER), ... | | 著者 | Shin, Y, Qayyum, M.Z, Murakami, K.S. | | 登録日 | 2020-10-21 | | 公開日 | 2020-12-09 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.58 Å) | | 主引用文献 | Structural basis of ribosomal RNA transcription regulation.
Nat Commun, 12, 2021
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6WMT
 | | F. tularensis RNAPs70-(MglA-SspA)-ppGpp-PigR-iglA DNA complex | | 分子名称: | DNA NT-strand, DNA NT-strand downstream, DNA T-strand, ... | | 著者 | Travis, B.A, Brennan, R.G, Schumacher, M.A. | | 登録日 | 2020-04-21 | | 公開日 | 2020-11-11 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.43 Å) | | 主引用文献 | Structural Basis for Virulence Activation of Francisella tularensis.
Mol.Cell, 81, 2021
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6WMR
 | | F. tularensis RNAPs70-(MglA-SspA)-iglA DNA complex | | 分子名称: | DNA NT-strand, DNA NT-strand downstream, DNA T-strand, ... | | 著者 | Travis, B.A, Brennan, R.G, Schumacher, M.A. | | 登録日 | 2020-04-21 | | 公開日 | 2020-11-11 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | | 主引用文献 | Structural Basis for Virulence Activation of Francisella tularensis.
Mol.Cell, 81, 2021
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6WMU
 | | E. coli RNAPs70-SspA-gadA DNA complex | | 分子名称: | DNA NT-strand, DNA NT-strand downstream, DNA T-strand, ... | | 著者 | Travis, B.A, Brennan, R.G, Schumacher, M.A. | | 登録日 | 2020-04-21 | | 公開日 | 2020-11-11 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | | 主引用文献 | Structural Basis for Virulence Activation of Francisella tularensis.
Mol.Cell, 81, 2021
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7KHB
 | | Escherichia coli RNA polymerase and rrnBP1 promoter open complex | | 分子名称: | CHAPSO, DNA (60-MER), DNA (64-MER), ... | | 著者 | Shin, Y, Qayyum, M.Z, Murakami, K.S. | | 登録日 | 2020-10-20 | | 公開日 | 2020-10-28 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.53 Å) | | 主引用文献 | Structural basis of ribosomal RNA transcription regulation.
Nat Commun, 12, 2021
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7KHC
 | | Escherichia coli RNA polymerase and rrnBP1 promoter closed complex | | 分子名称: | CHAPSO, DNA (18 MER), DNA (63-MER), ... | | 著者 | Shin, Y, Qayyum, M.Z, Murakami, K.S. | | 登録日 | 2020-10-20 | | 公開日 | 2020-10-28 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.14 Å) | | 主引用文献 | Structural basis of ribosomal RNA transcription regulation.
Nat Commun, 12, 2021
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7KHI
 | | Escherichia coli RNA polymerase and rrnBP1 promoter complex with DksA/ppGpp | | 分子名称: | CHAPSO, DNA (28-MER), DNA (36-MER), ... | | 著者 | Shin, Y, Qayyum, M.Z, Murakami, K.S. | | 登録日 | 2020-10-21 | | 公開日 | 2020-10-28 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.62 Å) | | 主引用文献 | Structural basis of ribosomal RNA transcription regulation.
Nat Commun, 12, 2021
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6VVZ
 | | Mycobacterium tuberculosis RNAP S456L mutant transcription initiation intermediate structure with Sorangicin | | 分子名称: | DNA (62-MER), DNA (65-MER), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Lilic, M, Boyaci, H, Chen, J, Darst, S.A, Campbell, E.A. | | 登録日 | 2020-02-18 | | 公開日 | 2020-10-21 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.72 Å) | | 主引用文献 | The antibiotic sorangicin A inhibits promoter DNA unwinding in a Mycobacterium tuberculosis rifampicin-resistant RNA polymerase.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6VVY
 | | Mycobacterium tuberculosis WT RNAP transcription open promoter complex with Sorangicin | | 分子名称: | DNA (65-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Lilic, M, Boyaci, H, Chen, J, Darst, S.A, Campbell, E.A. | | 登録日 | 2020-02-18 | | 公開日 | 2020-10-21 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.42 Å) | | 主引用文献 | The antibiotic sorangicin A inhibits promoter DNA unwinding in a Mycobacterium tuberculosis rifampicin-resistant RNA polymerase.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6VVV
 | | Crystal structure of a Mycobacterium smegmatis transcription initiation complex with Rifampicin-resistant RNA polymerase | | 分子名称: | DNA (26-MER), DNA (31-MER), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Lilic, M, Darst, S.A, Campbell, E.A. | | 登録日 | 2020-02-18 | | 公開日 | 2020-10-21 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | The antibiotic sorangicin A inhibits promoter DNA unwinding in a Mycobacterium tuberculosis rifampicin-resistant RNA polymerase.
Proc.Natl.Acad.Sci.USA, 117, 2020
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