PDB: 470 件ウェブページステータス検索Chemie searchBIRD

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8DTO	Vaccine elicited Antibody MU89 bound to CH848.D949.10.17_N133D_N138T.DS.SOSIP.664 HIV-1 Env trimer 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Stalls, V, Acharya, P. 登録日 2022-07-26 公開日 2023-04-19 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.57 Å) 主引用文献 Mutation-guided vaccine design: A process for developing boosting immunogens for HIV broadly neutralizing antibody induction. Cell Host Microbe, 32, 2024
8DP1	Cryo-EM structure of HIV-1 Env(BG505.T332N SOSIP) in complex with DH1030.1 Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DH1030.1 Fab Heavy chain, ... 著者 Gobeil, S, Acharya, P. 登録日 2022-07-14 公開日 2023-07-19 実験手法 ELECTRON MICROSCOPY (3.46 Å) 主引用文献 Shared recognition mechanism for HIV-1 envelope-reactive V3 glycan broadly neutralizing B cell lineage maturation in humans and macaques To Be Published
8DOW	Cryo-EM structure of HIV-1 Env(CH848 10.17 DS.SOSIP_DT) in complex with DH1030.1 Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DH1030.1 Fab Heavy chain, ... 著者 Gobeil, S, Acharya, P. 登録日 2022-07-14 公開日 2023-07-19 実験手法 ELECTRON MICROSCOPY (3.69 Å) 主引用文献 Shared recognition mechanism for HIV-1 envelope-reactive V3 glycan broadly neutralizing B cell lineage maturation in humans and macaques To Be Published
8DOK	Cryo-EM structure of T/F100 SOSIP.664 HIV-1 Env trimer in complex with 8ANC195 and 10-1074 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Chen, Y, Zhou, F, Huang, R, Tolbert, W, Pazgier, M. 登録日 2022-07-13 公開日 2023-07-19 最終更新日 2023-11-08 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir. Nat Commun, 14, 2023
8DCQ	CRYSTAL STRUCTURE OF HIV-1 LM/HT CLADE A/E CRF01 GP120 CORE IN COMPLEX WITH YIR-821 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HIV-1 LM/HT Clade A/E CRF01 gp120 core, ... 著者 Tolbert, W.D, Pazgier, M. 登録日 2022-06-17 公開日 2023-01-11 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Characterization of a Novel CD4 Mimetic Compound YIR-821 against HIV-1 Clinical Isolates. J.Virol., 97, 2023
8D5C	anti-HIV-1 gp120-sCD4 complex antibody CG10 Fab in complex with B41-sCD4 分子名称: CG10 Fab heavy chain, CG10 Fab light chain, Envelope glycoprotein gp160, ... 著者 Yang, Z, Bjorkman, P.J, Gershoni, J.M. 登録日 2022-06-04 公開日 2022-11-16 最終更新日 2023-01-04 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Antibody Recognition of CD4-Induced Open HIV-1 Env Trimers. J.Virol., 96, 2022
8D0Y	Crystal Structure of HIV-1 BG505 SOSIPv8 Trimer in Complex with CD4bs targeting antibody 21N13 and interface targeting antibody 35O22 at 4.7 Angstrom 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22scFv Heavy Chain Variable, ... 著者 Xian, Y, Wilson, I.A. 登録日 2022-05-26 公開日 2023-07-19 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (4.7 Å) 主引用文献 The domain-swaped dimer of the HIV-1 CD4bs targeting antibody 21N13 To Be Published
8CZZ	Cryo-EM structure of T/F100 SOSIP.664 HIV-1 Env trimer with LMHS mutations in complex with Temsavir, 8ANC195, and 10-1074 分子名称: 1-[4-(benzenecarbonyl)piperazin-1-yl]-2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]ethane-1,2-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Chen, Y, Pozharski, E, Tolbert, W, Pazgier, M. 登録日 2022-05-25 公開日 2023-05-31 最終更新日 2023-11-08 実験手法 ELECTRON MICROSCOPY (3.14 Å) 主引用文献 Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir. Nat Commun, 14, 2023
8C8T	cryo-EM structure of BG505 SOSIP.664 HIV-1 Env trimer in complex with bNAbs EPTC112 and 3BNC117 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... 著者 Baquero, E, Molinos-Albert, L, Mouquet, H. 登録日 2023-01-21 公開日 2023-07-05 最終更新日 2023-08-23 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Anti-V1/V3-glycan broadly HIV-1 neutralizing antibodies in a post-treatment controller. Cell Host Microbe, 31, 2023
7UR6	Cryo-EM structure of SHIV-elicited, FP-directed Rhesus Fab RM6561.DH1021.14 in complex with stabilized HIV-1 Env Ce1176 DS-SOSIP.664 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy Chain, ... 著者 Gorman, J, Kwong, P.D. 登録日 2022-04-21 公開日 2023-04-26 実験手法 ELECTRON MICROSCOPY (3.46 Å) 主引用文献 Cryo-EM structure of SHIV-elicited, FP-directed Rhesus Fab RM6561.DH1021.14 in complex with stabilized HIV-1 Env Ce1176 DS-SOSIP.664 To Be Published
7UOJ	The CryoEM structure of N49-P9.6-FR3 and PGT121 Fabs in complex with BG505 SOSIP.664 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... 著者 Nguyen, D.N, Tolbert, W.D, Pazgier, M. 登録日 2022-04-13 公開日 2023-05-03 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.02 Å) 主引用文献 The structure of N49-P9.6-FR3 and PGT121 Fabs in complex with BG505 SOSIP To Be Published
7UGQ	Cryo-EM structure of BG24 Fabs with an inferred germline CDRL1 and 10-1074 Fabs in complex with HIV-1 Env 6405-SOSIP.664 分子名称: 10-1074 Fab heavy chain, 10-1074 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Dam, K.A, Bjorkman, P.J. 登録日 2022-03-25 公開日 2022-11-09 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design. Nat Commun, 13, 2022
7UGP	Cryo-EM structure of BG24 Fabs with an inferred germline light chain and 10-1074 Fabs in complex with HIV-1 Env immunogen BG505-SOSIPv4.1-GT1 containing the N276 gp120 glycan- Class 1 分子名称: 10-1074 Fab heavy chain, 10-1074 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Dam, K.A, Bjorkman, P.J. 登録日 2022-03-25 公開日 2022-11-09 最終更新日 2022-11-16 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design. Nat Commun, 13, 2022
7UGO	Cryo-EM structure of BG24 inferred germline Fabs with mature CDR3s and 10-1074 Fabs in complex with HIV-1 Env immunogen BG505-SOSIPv4.1-GT1 分子名称: 10-1074 Fab heavy chain, 10-1074 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Dam, K.A, Bjorkman, P.J. 登録日 2022-03-25 公開日 2022-10-26 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design. Nat Commun, 13, 2022
7UGN	Cryo-EM structure of BG24 inferred germline Fabs with germline CDR3s and 10-1074 Fabs in complex with HIV-1 Env immunogen BG505-SOSIPv4.1-GT1 - Class 1 分子名称: 10-1074 Fab heavy chain, 10-1074 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Dam, K.A, Bjorkman, P.J. 登録日 2022-03-25 公開日 2022-10-26 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design. Nat Commun, 13, 2022
7UCG	Structure of the DU422 SOSIP.664 trimer in complex with neutralizing antibody Fab fragments 10-1074 and BG24 分子名称: 10-1074 Fab heavy chain, 10-1074 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Barnes, C.O, Bjorkman, P.J. 登録日 2022-03-16 公開日 2022-08-17 最終更新日 2022-09-07 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 A naturally arising broad and potent CD4-binding site antibody with low somatic mutation. Sci Adv, 8, 2022
7UCF	Structure of the BG505 SOSIP.664 trimer in complex with neutralizing antibody Fab fragments 10-1074 and BG24 分子名称: 10-1074 Fab heavy chain, 10-1074 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Barnes, C.O, Bjorkman, P.J. 登録日 2022-03-16 公開日 2022-08-17 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 A naturally arising broad and potent CD4-binding site antibody with low somatic mutation. Sci Adv, 8, 2022
7TXD	Cryo-EM structure of BG505 SOSIP HIV-1 Env trimer in complex with CD4 receptor (D1D2) and broadly neutralizing darpin bnD.9 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Broadly neutralizing darpin bnd.9, ... 著者 Cerutti, G, Gorman, J, Kwong, P.D, Shapiro, L. 登録日 2022-02-08 公開日 2023-04-12 最終更新日 2023-09-27 実験手法 ELECTRON MICROSCOPY (3.87 Å) 主引用文献 Trapping the HIV-1 V3 loop in a helical conformation enables broad neutralization. Nat.Struct.Mol.Biol., 30, 2023
7TJP	HIV-1 gp120 complex with CJF-II-195 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein 120, IMIDAZOLE, ... 著者 Gong, Z, Hendrickson, W.A. 登録日 2022-01-16 公開日 2023-01-25 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.77 Å) 主引用文献 Structural and Functional Characterization of Indane-Core CD4-Mimetic Compounds Substituted with Heterocyclic Amines Acs Medicinal Chemistry Letters, 14, 2023
7TJO	HIV-1 gp120 complex with CJF-II-197-S 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein 120, IMIDAZOLE, ... 著者 Gong, Z, Hendrickson, W.A. 登録日 2022-01-16 公開日 2023-01-25 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.07 Å) 主引用文献 Structural and Functional Characterization of Indane-Core CD4-Mimetic Compounds Substituted with Heterocyclic Amines ACS Medicinal Chemistry Letters, 14, 2023
7TFO	Cryo-EM structure of HIV-1 Env trimer BG505 SOSIP.664 in complex with CD4bs antibody Ab1573 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD4 binding site antibody Ab1573 - Fab heavy chain, ... 著者 Yang, Z, Bjorkman, P.J. 登録日 2022-01-06 公開日 2022-01-26 最終更新日 2022-02-23 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer. Nat Commun, 13, 2022
7TFN	Cryo-EM structure of CD4bs antibody Ab1303 in complex with HIV-1 Env trimer BG505 SOSIP.664 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-HIV-1 CD4bs antibody Fab Ab1303 - Heavy chain, ... 著者 Yang, Z, Bjorkman, P.J. 登録日 2022-01-06 公開日 2022-01-19 最終更新日 2022-02-23 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer. Nat Commun, 13, 2022
7TCO	Cryo-EM structure of CH235.12 in complex with HIV-1 Env trimer CH505TF.N279K.G458Y.SOSIP.664 with high-mannose glycans 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH235.12 Fab Heavy Chain, ... 著者 Manne, K, Henderson, R, Acharya, P. 登録日 2021-12-27 公開日 2023-08-02 実験手法 ELECTRON MICROSCOPY (4.19 Å) 主引用文献 Cryo-EM structure of CH235.12 in complex with HIV-1 Env trimer CH505TF.N279K.G458Y.SOSIP.664 To Be Published
7TCN	Cryo-EM structure of CH235.12 in complex with HIV-1 Env trimer CH505TF.N279K.SOSIP.664 with high-mannose glycans 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH235.12 Fab Heavy Chain, ... 著者 Manne, K, Henderson, R, Acharya, P. 登録日 2021-12-27 公開日 2023-08-02 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Cryo-EM structure of CH235.12 in complex with HIV-1 Env trimer CH505TF.N279K.G458Y.SOSIP.664 To Be Published
7T9T	Cryo-EM structure of CH235.12 in complex with HIV-1 Env trimer CH505TF.N279K.SOSIP.664 with complex glycans 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Manne, K, Acharya, P. 登録日 2021-12-20 公開日 2023-08-16 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Cryo-EM structure of CH235.12 in complex with HIV-1 Env trimer CH505TF.N279K.G458Y.SOSIP.664 To Be Published

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