8D0Y

Crystal Structure of HIV-1 BG505 SOSIPv8 Trimer in Complex with CD4bs targeting antibody 21N13 and interface targeting antibody 35O22 at 4.7 Angstrom

Summary for 8D0Y

• Entry DOI: 10.2210/pdb8d0y/pdb
• Related: 5CEZ 8D01
• Descriptor: 35O22scFv Heavy Chain Variable, alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (13 entities in total)
• Functional Keywords: hiv-1 cd4bs antibody; hiv-1 envelop protein;, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Macaca mulatta; More
• Total number of polymer chains: 6
• Total formula weight: 151906.51

Authors

Xian, Y.,Wilson, A. (deposition date: 2022-05-26, release date: 2023-07-19, Last modification date: 2023-11-22)

• Primary citation: Xian, Y.,Wilson, A.; The domain-swaped dimer of the HIV-1 CD4bs targeting antibody 21N13; To Be Published,

Experimental method

X-RAY DIFFRACTION (4.7 Å)