PDB: 319 件ウェブページステータス検索Chemie searchBIRD

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6B0R	Zinc finger Domain of WT1(-KTS form) with M342R Mutation and 14+1mer Oligonucleotide with 3' Triplet TGG 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*AP*GP*GP*GP*TP*TP*A)-3'), DNA (5'-D(P*TP*AP*AP*CP*CP*CP*TP*CP*CP*CP*AP*CP*GP*C)-3'), ... 著者 Horton, J.R, Cheng, X. 登録日 2017-09-14 公開日 2018-01-03 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.818 Å) 主引用文献 Role for first zinc finger of WT1 in DNA sequence specificity: Denys-Drash syndrome-associated WT1 mutant in ZF1 enhances affinity for a subset of WT1 binding sites. Nucleic Acids Res., 46, 2018
6BLW	Zinc finger Domain of WT1(+KTS form) with M342R Mutation and 17+1mer Oligonucleotide with Triplet GGT 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*TP*AP*AP*CP*CP*CP*TP*CP*CP*CP*AP*TP*TP*TP*CP*GP*C)-3'), DNA (5'-D(P*GP*CP*GP*AP*AP*AP*TP*GP*GP*GP*AP*GP*GP*GP*TP*T)-3'), ... 著者 Horton, J.R, Cheng, X. 登録日 2017-11-11 公開日 2018-01-03 最終更新日 2018-05-16 実験手法 X-RAY DIFFRACTION (1.835 Å) 主引用文献 Role for first zinc finger of WT1 in DNA sequence specificity: Denys-Drash syndrome-associated WT1 mutant in ZF1 enhances affinity for a subset of WT1 binding sites. Nucleic Acids Res., 46, 2018
6B0Q	Zinc finger Domain of WT1(-KTS form) with 13+1mer Oligonucleotide with 3' Triplet TGT 分子名称: DNA (5'-D(P*AP*AP*CP*AP*CP*TP*CP*CP*CP*AP*CP*GP*C)-3'), DNA (5'-D(P*GP*CP*GP*TP*GP*GP*GP*AP*GP*TP*GP*TP*T)-3'), SULFATE ION, ... 著者 Horton, J.R, Cheng, X. 登録日 2017-09-14 公開日 2018-01-03 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.794 Å) 主引用文献 Role for first zinc finger of WT1 in DNA sequence specificity: Denys-Drash syndrome-associated WT1 mutant in ZF1 enhances affinity for a subset of WT1 binding sites. Nucleic Acids Res., 46, 2018
5YJ3	Crystal structure of TZAP and telomeric DNA complex 分子名称: DNA (5'-D(*CP*CP*TP*AP*AP*CP*CP*CP*TP*AP*AP*CP*CP*CP*TP*AP*AP*C)-3'), DNA (5'-D(*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*G)-3'), Telomere zinc finger-associated protein, ... 著者 Li, F, Zhao, Y. 登録日 2017-10-07 公開日 2017-12-06 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.845 Å) 主引用文献 The 11th C2H2 zinc finger and an adjacent C-terminal arm are responsible for TZAP recognition of telomeric DNA. Cell Res., 28, 2018
5YEG	Crystal structure of CTCF ZFs4-8-Hs5-1a complex 分子名称: DNA (5'-D(*AP*CP*TP*TP*TP*AP*AP*CP*CP*AP*GP*CP*AP*GP*AP*GP*GP*GP*CP*G)-3'), DNA (5'-D(*TP*CP*GP*CP*CP*CP*TP*CP*TP*GP*CP*TP*GP*GP*TP*TP*AP*AP*AP*G)-3'), Transcriptional repressor CTCF, ... 著者 Yin, M, Wang, J, Wang, M, Li, X. 登録日 2017-09-17 公開日 2017-11-29 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Molecular mechanism of directional CTCF recognition of a diverse range of genomic sites Cell Res., 27, 2017
5YEL	Crystal structure of CTCF ZFs6-11-gb7CSE 分子名称: DNA (26-MER), Transcriptional repressor CTCF, ZINC ION 著者 Yin, M, Wang, J, Wang, M, Li, X, Wang, Y. 登録日 2017-09-18 公開日 2017-11-29 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.96 Å) 主引用文献 Molecular mechanism of directional CTCF recognition of a diverse range of genomic sites Cell Res., 27, 2017
5YEH	Crystal structure of CTCF ZFs4-8-eCBS 分子名称: DNA (5'-D(*AP*CP*GP*GP*TP*TP*TP*CP*CP*GP*CP*TP*AP*GP*AP*GP*GP*GP*CP*G)-3'), DNA (5'-D(*TP*CP*GP*CP*CP*CP*TP*CP*TP*AP*GP*CP*GP*GP*AP*AP*AP*CP*CP*G)-3'), Transcriptional repressor CTCF, ... 著者 Yin, M, Wang, J, Wang, M, Li, X, Wang, Y. 登録日 2017-09-17 公開日 2017-11-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.328 Å) 主引用文献 Molecular mechanism of directional CTCF recognition of a diverse range of genomic sites Cell Res., 27, 2017
5YEF	Crystal structure of CTCF ZFs2-8-Hs5-1aE 分子名称: DNA (27-MER), Transcriptional repressor CTCF, ZINC ION 著者 Yin, M, Wang, J, Wang, M, Li, X, Wang, Y. 登録日 2017-09-17 公開日 2017-11-29 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.807 Å) 主引用文献 Molecular mechanism of directional CTCF recognition of a diverse range of genomic sites Cell Res., 27, 2017
5V3G	PRDM9-allele-C ZnF8-13 分子名称: DNA (5'-D(*AP*GP*GP*GP*CP*AP*AP*CP*GP*CP*TP*CP*AP*CP*TP*GP*GP*GP*GP*TP*C)-3'), DNA (5'-D(*TP*GP*AP*CP*CP*CP*CP*AP*GP*TP*GP*AP*GP*CP*GP*TP*TP*GP*CP*CP*C)-3'), PR domain zinc finger protein 9, ... 著者 Patel, A, Cheng, X. 登録日 2017-03-07 公開日 2017-08-23 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.416 Å) 主引用文献 Structural basis of human PR/SET domain 9 (PRDM9) allele C-specific recognition of its cognate DNA sequence. J. Biol. Chem., 292, 2017
5K5L	Homo sapiens CCCTC-binding factor (CTCF) ZnF6-8 and H19 sequence DNA complex structure 分子名称: DNA (5'-D(*GP*TP*TP*GP*CP*CP*GP*CP*GP*TP*G)-3'), DNA (5'-D(P*AP*CP*GP*CP*GP*GP*CP*AP*AP*C)-3'), Transcriptional repressor CTCF, ... 著者 Hashimoto, H, Cheng, X. 登録日 2016-05-23 公開日 2017-05-24 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3.125 Å) 主引用文献 Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA. Mol. Cell, 66, 2017
5K5H	Homo sapiens CCCTC-binding factor (CTCF) ZnF4-7 and DNA complex structure 分子名称: DNA (5'-D(*CP*AP*GP*CP*AP*GP*GP*GP*GP*GP*CP*GP*C)-3'), DNA (5'-D(*CP*GP*CP*CP*CP*CP*CP*TP*GP*CP*TP*GP*G)-3'), Transcriptional repressor CTCF, ... 著者 Hashimoto, H, Cheng, X. 登録日 2016-05-23 公開日 2017-05-24 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3.108 Å) 主引用文献 Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA. Mol. Cell, 66, 2017
5K5J	Homo sapiens CCCTC-binding factor (CTCF) ZnF5-8 and DNA complex structure in space group P41212 分子名称: ACETATE ION, DNA (5'-D(*CP*CP*CP*TP*GP*CP*TP*GP*GP*CP*AP*AP*C)-3'), DNA (5'-D(*TP*TP*GP*CP*CP*AP*GP*CP*AP*GP*GP*GP*G)-3'), ... 著者 Hashimoto, H, Cheng, X. 登録日 2016-05-23 公開日 2017-05-24 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.287 Å) 主引用文献 Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA. Mol. Cell, 66, 2017
5KKQ	Homo sapiens CCCTC-binding factor (CTCF) ZnF3-7 and DNA complex structure 分子名称: DNA (5'-D(*GP*CP*CP*AP*GP*CP*AP*GP*GP*GP*GP*GP*CP*GP*CP*TP*A)-3'), DNA (5'-D(*TP*AP*GP*CP*GP*CP*CP*CP*CP*CP*TP*GP*CP*TP*GP*GP*C)-3'), Transcriptional repressor CTCF, ... 著者 Hashimoto, H, Wang, D, Cheng, X. 登録日 2016-06-22 公開日 2017-05-24 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.744 Å) 主引用文献 Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA. Mol. Cell, 66, 2017
5T00	Human CTCF ZnF3-7 and methylated DNA complex 分子名称: DNA (5'-GCCAGCAGGGGG(5CM)GCTA-3'), DNA (5'-TAG(5CM)GCCCCCTGCTGGC-3'), Transcriptional repressor CTCF, ... 著者 Hashimoto, H, Wang, D, Cheng, X. 登録日 2016-08-15 公開日 2017-05-24 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA. Mol. Cell, 66, 2017
5T0U	CTCF ZnF2-7 and DNA complex structure 分子名称: DNA (5'-D(*CP*CP*TP*CP*AP*CP*TP*AP*GP*CP*GP*CP*CP*CP*CP*CP*TP*GP*CP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*GP*CP*AP*GP*GP*GP*GP*GP*CP*GP*CP*TP*AP*GP*TP*GP*AP*GP*G)-3'), Transcriptional repressor CTCF, ... 著者 Hashimoto, H, Wang, D, Cheng, X. 登録日 2016-08-16 公開日 2017-05-24 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3.199 Å) 主引用文献 Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA. Mol. Cell, 66, 2017
5K5I	Homo sapiens CCCTC-binding factor (CTCF) ZnF5-8 and DNA complex structure in space group P65 分子名称: DNA (5'-D(*CP*CP*CP*TP*GP*CP*TP*GP*GP*CP*AP*CP*C)-3'), DNA (5'-D(*GP*TP*GP*CP*CP*AP*GP*CP*AP*GP*GP*GP*G)-3'), SULFATE ION, ... 著者 Hashimoto, H, Cheng, X. 登録日 2016-05-23 公開日 2017-05-24 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA. Mol. Cell, 66, 2017
5UND	Crystal Structure of CTCF(ZnF 4-10) With 28-mer DNA 分子名称: 1,2-ETHANEDIOL, DNA (26-MER), GLYCEROL, ... 著者 Horton, J.R, Cheng, X. 登録日 2017-01-30 公開日 2017-05-24 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.549 Å) 主引用文献 Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA. Mol. Cell, 66, 2017
5N14	NMR structure calculation of a composite Cys2His2 type zinc finger protein containing a non-peptide (or oligourea) helical domain 分子名称: Protein (chimeric oligourea-peptide zinc finger), ZINC ION 著者 Venkateshaiah M, V.K, Salgado, G. 登録日 2017-02-05 公開日 2017-04-12 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 NMR structure calculation of a composite Cys2His2 type zinc finger protein containing a non-peptide (or oligourea) helical domain. To Be Published
5KE8	mouse Klf4 E446P ZnF1-3 and MpG/MpG sequence DNA complex structure 分子名称: DNA (5'-D(*GP*AP*GP*GP*(5CM)P*GP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*(5CM)P*GP*CP*CP*TP*C)-3'), Krueppel-like factor 4, ... 著者 Hashimoto, H, Cheng, X. 登録日 2016-06-09 公開日 2016-09-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Distinctive Klf4 mutants determine preference for DNA methylation status. Nucleic Acids Res., 44, 2016
5KL7	Wilms Tumor Protein (WT1) ZnF2-4Q369R in complex with carboxylated DNA 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*(1CC)P*GP*T)-3'), DNA (5'-D(*TP*AP*(5CM)P*GP*CP*CP*CP*AP*CP*GP*C)-3'), ... 著者 Hashimoto, H, Cheng, X. 登録日 2016-06-23 公開日 2016-09-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.579 Å) 主引用文献 Denys-Drash syndrome associated WT1 glutamine 369 mutants have altered sequence-preferences and altered responses to epigenetic modifications. Nucleic Acids Res., 44, 2016
5KE9	mouse Klf4 E446P ZnF1-3 and TpG/CpA sequence DNA complex structure 分子名称: DNA (5'-D(*GP*AP*GP*GP*TP*GP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*CP*AP*CP*CP*TP*C)-3'), Krueppel-like factor 4, ... 著者 Hashimoto, H, Cheng, X. 登録日 2016-06-09 公開日 2016-09-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.336 Å) 主引用文献 Distinctive Klf4 mutants determine preference for DNA methylation status. Nucleic Acids Res., 44, 2016
5KEA	mouse Klf4 ZnF1-3 (E446D) and CpG/CpG sequence DNA complex structure: Form I 分子名称: DNA (5'-D(*GP*AP*GP*GP*CP*GP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*CP*GP*CP*CP*TP*C)-3'), Krueppel-like factor 4, ... 著者 Hashimoto, H, Cheng, X. 登録日 2016-06-09 公開日 2016-09-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.458 Å) 主引用文献 Distinctive Klf4 mutants determine preference for DNA methylation status. Nucleic Acids Res., 44, 2016
5KL6	Wilms Tumor Protein (WT1) Q369R ZnF2-4 in complex with DNA 分子名称: DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*GP*GP*T)-3'), DNA (5'-D(*TP*AP*CP*CP*CP*CP*CP*AP*CP*GP*C)-3'), Wilms tumor protein, ... 著者 Hashimoto, H, Cheng, X. 登録日 2016-06-23 公開日 2016-09-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.641 Å) 主引用文献 Denys-Drash syndrome associated WT1 glutamine 369 mutants have altered sequence-preferences and altered responses to epigenetic modifications. Nucleic Acids Res., 44, 2016
5KL4	Wilms Tumor Protein (WT1) ZnF2-4 Q369H in complex with formylated DNA 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*(5FC)P*GP*T)-3'), ... 著者 Hashimoto, H, Cheng, X. 登録日 2016-06-23 公開日 2016-09-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.783 Å) 主引用文献 Denys-Drash syndrome associated WT1 glutamine 369 mutants have altered sequence-preferences and altered responses to epigenetic modifications. Nucleic Acids Res., 44, 2016
5KL5	Wilms Tumor Protein (WT1) ZnF2-4 Q369H in complex with carboxylated DNA 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*(1CC)P*GP*T)-3'), DNA (5'-D(*TP*AP*(5CM)P*GP*CP*CP*CP*AP*CP*GP*C)-3'), ... 著者 Hashimoto, H, Cheng, X. 登録日 2016-06-23 公開日 2016-09-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.289 Å) 主引用文献 Denys-Drash syndrome associated WT1 glutamine 369 mutants have altered sequence-preferences and altered responses to epigenetic modifications. Nucleic Acids Res., 44, 2016

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