PDB: 257 件ウェブページステータス検索Chemie searchBIRD

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7ZEZ	Trimolecular complex Cyp33-RRMdelta alpha : MLL1-PHD3 : H3K4me3 分子名称: Histone H3, Isoform 3 of Peptidyl-prolyl cis-trans isomerase E, MLL cleavage product N320, ... 著者 Blatter, M, Allain, F, Meylan, C. 登録日 2022-03-31 公開日 2022-04-13 最終更新日 2023-05-03 実験手法 SOLUTION NMR 主引用文献 RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription. Sci Adv, 9, 2023
3LX7	Crystal structure of a Novel Tudor domain-containing protein SGF29 分子名称: SAGA-associated factor 29 homolog, SULFATE ION, UNKNOWN ATOM OR ION 著者 Bian, C.B, Xu, C, Tempel, W, Lam, R, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Bochkarev, A, Min, J. 登録日 2010-02-24 公開日 2010-05-05 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation. Embo J., 30, 2011
3MET	Crystal structure of SGF29 in complex with H3K4me2 分子名称: GLYCEROL, Histone H3, SAGA-associated factor 29 homolog, ... 著者 Bian, C.B, Xu, C, Lam, R, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) 登録日 2010-03-31 公開日 2010-04-28 最終更新日 2011-08-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation. Embo J., 30, 2011
5JSG	Crystal structure of Spindlin1 bound to compound EML405 分子名称: CHLORIDE ION, MAGNESIUM ION, Spindlin-1, ... 著者 Su, X, Li, H. 登録日 2016-05-08 公開日 2017-05-10 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Developing Spindlin1 small-molecule inhibitors by using protein microarrays Nat. Chem. Biol., 13, 2017
5JSJ	Crystal structure of Spindlin1 bound to compound EML631 分子名称: CHLORIDE ION, MAGNESIUM ION, Spindlin-1, ... 著者 Su, X, Li, H. 登録日 2016-05-08 公開日 2017-05-24 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.348 Å) 主引用文献 Developing Spindlin1 small-molecule inhibitors by using protein microarrays Nat. Chem. Biol., 13, 2017
3SOW	Structure of UHRF1 PHD finger in complex with histone H3K4me3 1-9 peptide 分子名称: E3 ubiquitin-protein ligase UHRF1, Histone H3, ZINC ION 著者 Rajakumara, E, Patel, D.J. 登録日 2011-06-30 公開日 2011-08-03 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.9501 Å) 主引用文献 PHD Finger Recognition of Unmodified Histone H3R2 Links UHRF1 to Regulation of Euchromatic Gene Expression. Mol.Cell, 43, 2011
3MP8	Crystal structure of Sgf29 tudor domain 分子名称: 4-(HYDROXYMETHYL)BENZAMIDINE, ACETIC ACID, GLYCEROL, ... 著者 Li, J, Wu, M, Ruan, J, Zang, J. 登録日 2010-04-26 公開日 2011-05-04 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation Embo J., 30, 2011
5Y20	Crystal structure of AL1 PHD finger bound to H3K4me3 分子名称: PEPTIDE FROM HISTONE H3, PHD finger protein ALFIN-LIKE 1, ZINC ION 著者 Zhao, S, Zhang, B, Li, H. 登録日 2017-07-22 公開日 2018-01-24 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.409 Å) 主引用文献 Systematic Profiling of Histone Readers in Arabidopsis thaliana. Cell Rep, 22, 2018
5Y5W	Crystal structure of human Spindlin1 in complex with a histone H4K20(me3) peptide 分子名称: Histone peptide H4K20(me3), Spindlin-1 著者 Wang, C, Zang, J. 登録日 2017-08-10 公開日 2017-10-11 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Spindlin-1 recognizes methylations of K20 and R23 of histone H4 tail FEBS Lett., 592, 2018
3GL6	Crystal structure of JARID1A-PHD3 complexed with H3(1-9)K4me3 peptide 分子名称: Histone H3, Histone demethylase JARID1A, ZINC ION 著者 Wang, Z, Song, J, Patel, D.J. 登録日 2009-03-11 公開日 2009-05-05 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger. Nature, 459, 2009
4PLI	Structure of the chromodomain of MRG2 in complex with H3K36me3 分子名称: At1g02740, H3K36me3 著者 Liu, Y, Huang, Y. 登録日 2014-05-18 公開日 2015-07-22 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.651 Å) 主引用文献 Regulation of arabidopsis flowering by the histone mark readers MRG1/2 via interaction with CONSTANS to modulate FT expression. Plos Genet., 10, 2014
4PLL	Structure of the chromodaomain of MRG2 in complex with H3K36me3 分子名称: At1g02740, H3K36me3 著者 Liu, Y, Huang, Y. 登録日 2014-05-18 公開日 2015-07-22 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Regulation of arabidopsis flowering by the histone mark readers MRG1/2 via interaction with CONSTANS to modulate FT expression. Plos Genet., 10, 2014
7M10	PHF2 PHD Domain Complexed with Peptide From N-terminus of VRK1 分子名称: FORMIC ACID, Lysine-specific demethylase PHF2, Serine/threonine-protein kinase VRK1 N-terminus peptide, ... 著者 Horton, J.R, Cheng, X. 登録日 2021-03-11 公開日 2021-05-26 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Histone H3 N-terminal mimicry drives a novel network of methyl-effector interactions. Biochem.J., 478, 2021
8COK	Structural analysis of ING3 protein and its binding to histone H3 分子名称: Inhibitor of growth protein 3 著者 Ferreras-Gutierrez, M, Medrano, F.J, Blanco, F.J. 登録日 2023-02-28 公開日 2023-05-17 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.91 Å) 主引用文献 Structural analysis of ING3 protein and histone H3 binding. Int.J.Biol.Macromol., 242, 2023
2YB8	Crystal structure of Nurf55 in complex with Su(z)12 分子名称: POLYCOMB PROTEIN SU(Z)12, PROBABLE HISTONE-BINDING PROTEIN CAF1, SULFATE ION 著者 Schmitges, F.W, Prusty, A.B, Faty, M, Stutzer, A, Lingaraju, G.M, Aiwazian, J, Sack, R, Hess, D, Li, L, Zhou, S, Bunker, R.D, Wirth, U, Bouwmeester, T, Bauer, A, Ly-Hartig, N, Zhao, K, Chan, H, Gu, J, Gut, H, Fischle, W, Muller, J, Thoma, N.H. 登録日 2011-03-02 公開日 2011-05-18 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Histone Methylation by Prc2 is Inhibited by Active Chromatin Marks. Mol.Cell, 42, 2011
7BU9	Crystal Structure of Spindlin1-H3(K4me3-K9me2) complex 分子名称: H3(K4me3-K9me2) peptide, Spindlin-1 著者 Zhao, F, Li, H. 登録日 2020-04-05 公開日 2020-10-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.502 Å) 主引用文献 Molecular basis for histone H3 "K4me3-K9me3/2" methylation pattern readout by Spindlin1. J.Biol.Chem., 295, 2020
7BQZ	Crystal Structure of Spindlin1 bound to H3(K4me3-K9me3) peptide 分子名称: H3(K4me3-K9me3) peptide, Spindlin-1 著者 Zhao, F, Li, H. 登録日 2020-03-26 公開日 2020-10-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.101 Å) 主引用文献 Molecular basis for histone H3 "K4me3-K9me3/2" methylation pattern readout by Spindlin1. J.Biol.Chem., 295, 2020
6WXK	PHF23 PHD Domain Apo 分子名称: PHD finger protein 23, ZINC ION 著者 Vann, K.R, Zhang, J, Zhang, Y, Kutateladze, T. 登録日 2020-05-11 公開日 2020-07-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Mechanistic insights into chromatin targeting by leukemic NUP98-PHF23 fusion. Nat Commun, 11, 2020
2KGG	Solution Structure of JARID1A C-terminal PHD finger 分子名称: Histone demethylase JARID1A, ZINC ION 著者 Song, J, Wang, Z, Patel, D.J. 登録日 2009-03-11 公開日 2009-05-05 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger. Nature, 459, 2009
2KGI	Solution structure of JARID1A C-terminal PHD finger in complex with H3(1-9)K4me3 分子名称: H3(1-9)K4me3, Histone demethylase JARID1A, ZINC ION 著者 Song, J, Wang, Z, Patel, D.J. 登録日 2009-03-12 公開日 2009-05-05 最終更新日 2020-02-26 実験手法 SOLUTION NMR 主引用文献 Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger. Nature, 459, 2009
6W5I	Cryo-EM structure of MLL1 in complex with RbBP5, WDR5, SET1, and ASH2L bound to the nucleosome (Class01) 分子名称: DNA (147-MER), Histone H2A, Histone H2B 1.1, ... 著者 Park, S.H, Lee, Y.T, Ayoub, A, Dou, Y, Cho, U. 登録日 2020-03-13 公開日 2021-03-31 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (6.9 Å) 主引用文献 Mechanism for DPY30 and ASH2L intrinsically disordered regions to modulate the MLL/SET1 activity on chromatin. Nat Commun, 12, 2021
6W5N	Cryo-EM structure of MLL1 in complex with RbBP5, WDR5, SET1, and ASH2L bound to the nucleosome (Class05) 分子名称: DNA (147-MER), Histone H2A type 1, Histone H2B 1.1, ... 著者 Park, S.H, Lee, Y.T, Ayoub, A, Dou, Y, Cho, U. 登録日 2020-03-13 公開日 2021-03-31 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (6 Å) 主引用文献 Mechanism for DPY30 and ASH2L intrinsically disordered regions to modulate the MLL/SET1 activity on chromatin. Nat Commun, 12, 2021
6W5M	Cryo-EM structure of MLL1 in complex with RbBP5, WDR5, SET1, and ASH2L bound to the nucleosome (Class02) 分子名称: DNA (147-MER), Histone H2A type 1, Histone H2B 1.1, ... 著者 Park, S.H, Lee, Y.T, Ayoub, A, Dou, Y, Cho, U. 登録日 2020-03-13 公開日 2021-03-31 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Mechanism for DPY30 and ASH2L intrinsically disordered regions to modulate the MLL/SET1 activity on chromatin. Nat Commun, 12, 2021
5Z8L	crystal structure of Arabidopsis thaliana EBS in complex with an H3K27me3 peptide 分子名称: Chromatin remodeling protein EBS, H3K27me3 peptide, ZINC ION 著者 Yang, Z, Du, J. 登録日 2018-01-31 公開日 2018-07-25 最終更新日 2018-09-19 実験手法 X-RAY DIFFRACTION (2.005 Å) 主引用文献 EBS is a bivalent histone reader that regulates floral phase transition in Arabidopsis. Nat. Genet., 50, 2018
5Z8N	Crystal structure of Arabidopsis thaliana EBS C-terminal deletion construct in complex with an H3K4me2 peptide 分子名称: Chromatin remodeling protein EBS, H3K4me2 peptide, ZINC ION 著者 Yang, Z, Du, J. 登録日 2018-01-31 公開日 2018-07-25 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 EBS is a bivalent histone reader that regulates floral phase transition in Arabidopsis. Nat. Genet., 50, 2018

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