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4X9P
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BU of 4x9p by Molmil
Crystal structure of bovine Annexin A2
分子名称: Annexin A2, CALCIUM ION, CHLORIDE ION
著者Shumilin, I.A, Hollas, H, Vedeler, A, Kretsinger, R.H.
登録日2014-12-11
公開日2015-01-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献The native structure of annexin A2 peptides in hydrophilic environment determines their anti-angiogenic effects.
Biochem. Pharmacol., 95, 2015
4XBG
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BU of 4xbg by Molmil
Crystal structure of human 4E10 Fab in complex with phosphatidic acid (06:0 PA): 2.73 A resolution
分子名称: (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, 4E10 Fab heavy chain, 4E10 Fab light chain, ...
著者Irimia, A, Stanfield, R.L, Wilson, I.A.
登録日2014-12-16
公開日2016-02-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10.
Immunity, 44, 2016
4XCC
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Crystal structure of human 4E10 Fab crystalized in the presence of Phosphatidylcholine (06:0 PC); I422 space group
分子名称: 4E10 Fab Heavy chain, 4E10 Fab light chain, GLYCEROL
著者Irimia, A, Stanfield, R.L, Wilson, I.A.
登録日2014-12-17
公開日2016-02-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10.
Immunity, 44, 2016
4XC3
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Crystal structure of human 4E10 Fab in complex with its peptide epitope on HIV-1 gp41; crystals cryoprotected with rac-glycerol 1-phosphate
分子名称: 4E10 Fab heavy chain, 4E10 Fab light chain, MODIFIED FRAGMENT OF HIV-1 GLYCOPROTEIN (GP41) INCLUDING THE MPER REGION 671-683, ...
著者Irimia, A, Stanfield, R.L, Wilson, I.A.
登録日2014-12-17
公開日2016-02-03
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10.
Immunity, 44, 2016
4XCY
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BU of 4xcy by Molmil
Crystal structure of human 4E10 Fab in complex with phosphatidylglycerol (06:0 PG)
分子名称: (2S)-3-{[(R)-{[(2R)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-2-(hexanoyloxy)propyl hexanoate, 4E10 Fab heavy chain, 4E10 Fab light chain, ...
著者Irimia, A, Stanfield, R.L, Wilson, I.A.
登録日2014-12-18
公開日2016-02-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.96 Å)
主引用文献Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10.
Immunity, 44, 2016
6VKV
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BU of 6vkv by Molmil
Co-crystal structure of GS-6207 bound to HIV-1 capsid hexamer
分子名称: CHLORIDE ION, Capsid protein p24, IODIDE ION, ...
著者Bester, S.M, Kvaratskhelia, M.
登録日2020-01-22
公開日2020-10-21
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Structural and mechanistic bases for a potent HIV-1 capsid inhibitor.
Science, 370, 2020
6VPA
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BU of 6vpa by Molmil
Scabin (N110A) toxin from Streptomyces scabies
分子名称: Scabin
著者Lyons, B, Lidster, T, Merrill, A.R.
登録日2020-02-02
公開日2021-01-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Mapping the DNA-Binding Motif of Scabin Toxin, a Guanine Modifying Enzyme from Streptomyces scabies .
Toxins, 13, 2021
5ED3
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BU of 5ed3 by Molmil
crystal structure of human Hint1 complexing with AP5A
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE MONOPHOSPHATE, Histidine triad nucleotide-binding protein 1
著者Wang, J, Fang, P, Guo, M.
登録日2015-10-20
公開日2017-01-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.309 Å)
主引用文献Second messenger Ap4A polymerizes target protein HINT1 to transduce signals in Fc epsilon RI-activated mast cells.
Nat Commun, 10, 2019
5EDV
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BU of 5edv by Molmil
Structure of the HOIP-RBR/UbcH5B~ubiquitin transfer complex
分子名称: E3 ubiquitin-protein ligase RNF31, Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 D2, ...
著者Lechtenberg, B.C, Mace, P.D, Sanishvili, R, Riedl, S.J.
登録日2015-10-22
公開日2016-01-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.48 Å)
主引用文献Structure of a HOIP/E2~ubiquitin complex reveals RBR E3 ligase mechanism and regulation.
Nature, 529, 2016
4XAW
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BU of 4xaw by Molmil
Crystal structure of human 4E10 Fab in complex with its peptide epitope on HIV-1 gp41: Crystals cryoprotected with phosphatidic acid (08:0 PA)
分子名称: 4E10 Fab heavy chain, 4E10 Fab light chain, FRAGMENT OF HIV GLYCOPROTEIN (GP41) including the MPER region 671-683, ...
著者Irimia, A, Stanfield, R.L, Wilson, I.A.
登録日2014-12-15
公開日2016-02-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10.
Immunity, 44, 2016
6SWA
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BU of 6swa by Molmil
Mus musculus brain neocortex ribosome 60S bound to Ebp1
分子名称: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
著者Kraushar, M.L, Sprink, T.
登録日2019-09-20
公開日2020-09-30
最終更新日2021-02-17
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Protein Synthesis in the Developing Neocortex at Near-Atomic Resolution Reveals Ebp1-Mediated Neuronal Proteostasis at the 60S Tunnel Exit.
Mol.Cell, 81, 2021
6VUV
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BU of 6vuv by Molmil
Scabin (S117A) toxin from Streptomyces scabies
分子名称: Scabin
著者Lyons, B, Lidster, T, Merrill, A.R.
登録日2020-02-16
公開日2021-01-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Mapping the DNA-Binding Motif of Scabin Toxin, a Guanine Modifying Enzyme from Streptomyces scabies .
Toxins, 13, 2021
5EIB
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BU of 5eib by Molmil
Crystal structure of CPAP PN2-3 C-terminal loop-helix in complex with DARPin-tubulin
分子名称: Designed ankyrin repeat protein, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Li, H, Zheng, X.
登録日2015-10-29
公開日2016-10-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Molecular basis for CPAP-tubulin interaction in controlling centriolar and ciliary length
Nat Commun, 7, 2016
5EIT
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BU of 5eit by Molmil
Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the imidazopyridine derivative 2-(4-hydroxyphenyl)-3-(trifluoromethyl)imidazo[1,2-a]pyridin-6-ol
分子名称: 2-(4-hydroxyphenyl)-3-(trifluoromethyl)imidazo[1,2-a]pyridin-6-ol, Estrogen receptor, NCOA2
著者Nwachukwu, J.C, Srinivasan, S, Zheng, Y, Wang, S, Min, J, Dong, C, Liao, Z, Cavett, V, Nowak, J, Houtman, R, Carlson, K.E, Josan, J.S, Elemento, O, Katzenellenbogen, J.A, Zhou, H.B, Nettles, K.W.
登録日2015-10-30
公開日2016-05-04
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Predictive features of ligand-specific signaling through the estrogen receptor.
Mol.Syst.Biol., 12, 2016
6VVF
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BU of 6vvf by Molmil
Scabin (Y129H) toxin from Streptomyces scabies
分子名称: Scabin
著者Heney, K, Lyons, B, Merrill, A.R.
登録日2020-02-17
公開日2021-01-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Mapping the DNA-Binding Motif of Scabin Toxin, a Guanine Modifying Enzyme from Streptomyces scabies .
Toxins, 13, 2021
7AWV
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BU of 7awv by Molmil
Azoreductase (AzoRo) from Rhodococcus opacus 1CP
分子名称: DI(HYDROXYETHYL)ETHER, FLAVIN MONONUCLEOTIDE, FMN-dependent NADH-azoreductase, ...
著者Bento, I, Ngo, A, Qi, J, Juric, C, Tischler, D.
登録日2020-11-09
公開日2022-02-02
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Identification of molecular basis that underlie enzymatic specificity of AzoRo from Rhodococcus opacus 1CP: A potential NADH:quinone oxidoreductase.
Arch.Biochem.Biophys., 717, 2022
5GUH
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BU of 5guh by Molmil
Crystal structure of silkworm PIWI-clade Argonaute Siwi bound to piRNA
分子名称: MAGNESIUM ION, PIWI, RNA (28-MER)
著者Matsumoto, N, Nishimasu, H, Ishitani, R, Nureki, O.
登録日2016-08-29
公開日2016-10-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure of Silkworm PIWI-Clade Argonaute Siwi Bound to piRNA
Cell, 167, 2016
6UE3
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BU of 6ue3 by Molmil
Crystal structure of HCV NS3/4A D168A protease in complex with PC (JZ01-15)
分子名称: 1,2-ETHANEDIOL, GLYCEROL, NS3 protease, ...
著者Zephyr, J, Schiffer, C.A.
登録日2019-09-20
公開日2020-03-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Avoiding Drug Resistance by Substrate Envelope-Guided Design: Toward Potent and Robust HCV NS3/4A Protease Inhibitors.
Mbio, 11, 2020
5FEY
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BU of 5fey by Molmil
TRIM32 RING
分子名称: E3 ubiquitin-protein ligase TRIM32, ZINC ION
著者Rittinger, K, Esposito, D, Koliopoulos, M.G.
登録日2015-12-17
公開日2016-05-18
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Functional role of TRIM E3 ligase oligomerization and regulation of catalytic activity.
Embo J., 35, 2016
6VMY
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BU of 6vmy by Molmil
Structure of the B. subtilis cobalamin riboswitch
分子名称: Adenosylcobalamin, B. subtilis cobalamin riboswitch, COBALT HEXAMMINE(III), ...
著者Chan, C.W, Mondragon, A.
登録日2020-01-28
公開日2020-06-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Crystal structure of an atypical cobalamin riboswitch reveals RNA structural adaptability as basis for promiscuous ligand binding.
Nucleic Acids Res., 48, 2020
5FKK
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BU of 5fkk by Molmil
TetR(D) N82A mutant in complex with anhydrotetracycline and magnesium
分子名称: 5A,6-ANHYDROTETRACYCLINE, CHLORIDE ION, MAGNESIUM ION, ...
著者Werten, S, Schneider, J, Palm, G.J, Hinrichs, W.
登録日2015-10-17
公開日2016-04-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Modular Organisation of Inducer Recognition and Allostery in the Tetracycline Repressor
FEBS J., 283, 2016
6VWS
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BU of 6vws by Molmil
Hexamer of Helical HIV capsid by RASTR method
分子名称: HIV capsid protein
著者Zhao, H, Iqbal, N, Asturias, F, Kvaratskhelia, M, Vanblerkom, P.
登録日2020-02-20
公開日2020-10-21
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (6.08 Å)
主引用文献Structural and mechanistic bases for a potent HIV-1 capsid inhibitor.
Science, 370, 2020
5DVS
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BU of 5dvs by Molmil
Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with a 2-Methyl-substituted Triaryl-imine 4,4'-[(2-methylphenyl)carbonimidoyl]diphenol
分子名称: 4,4'-[(2-methylphenyl)carbonimidoyl]diphenol, Estrogen receptor, Nuclear receptor coactivator 2
著者Nwachukwu, J.C, Wright, N.J, Srinivasan, S, Zheng, Y, Wang, S, Min, J, Dong, C, Liao, Z, Cavett, V, Nowak, J, Houtman, R, Carlson, K.E, Josan, J.S, Elemento, O, Katzenellenbogen, J.A, Zhou, H.B, Nettles, K.W.
登録日2015-09-21
公開日2016-05-04
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Predictive features of ligand-specific signaling through the estrogen receptor.
Mol.Syst.Biol., 12, 2016
5DWS
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BU of 5dws by Molmil
Crystal Structure of ITCH WW3 domain in complex with TXNIP peptide
分子名称: E3 ubiquitin-protein ligase Itchy homolog, UNKNOWN ATOM OR ION, txnip
著者Liu, Y, Tempel, W, Dong, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2015-09-22
公開日2015-10-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal Structure of ITCH WW3 domain in complex with TXNIP peptide
to be published
7QP7
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BU of 7qp7 by Molmil
Structure of the human 48S initiation complex in closed state (h48S AUG closed)
分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Yi, S.-H, Petrychenko, V, Schliep, J.E, Goyal, A, Linden, A, Chari, A, Urlaub, H, Stark, H, Rodnina, M.V, Adio, S, Fischer, N.
登録日2022-01-03
公開日2022-05-11
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Conformational rearrangements upon start codon recognition in human 48S translation initiation complex.
Nucleic Acids Res., 50, 2022

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