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7QO1
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BU of 7qo1 by Molmil
complex of DNA ligase I and FEN1 on PCNA and DNA
分子名称: ADENOSINE MONOPHOSPHATE, DNA ligase 1, Flap endonuclease 1, ...
著者Blair, K, Tehseen, M, Raducanu, V.S, Shahid, T, Lancey, C, Cruehet, R, Hamdan, S, De Biasio, A.
登録日2021-12-23
公開日2023-01-11
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Mechanism of human Lig1 regulation by PCNA in Okazaki fragment sealing.
Nat Commun, 13, 2022
6ZAB
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BU of 6zab by Molmil
Structure of the transcriptional repressor Atu1419 (VanR) from agrobacterium fabrum in complex a palindromic DNA (P6422 space group)
分子名称: 1,2-ETHANEDIOL, CITRIC ACID, DI(HYDROXYETHYL)ETHER, ...
著者Morera, S, Naretto, A, Vigouroux, A, Legrand, P.
登録日2020-06-05
公開日2020-12-02
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Characterization of the first tetrameric transcription factor of the GntR superfamily with allosteric regulation from the bacterial pathogen Agrobacterium fabrum.
Nucleic Acids Res., 49, 2021
3D09
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BU of 3d09 by Molmil
Human p53 core domain with hot spot mutation R249S and second-site suppressor mutations H168R and T123A
分子名称: Cellular tumor antigen p53, ZINC ION
著者Rozenberg, H, Suad, O, Shakked, Z.
登録日2008-05-01
公開日2009-01-20
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis of restoring sequence-specific DNA binding and transactivation to mutant p53 by suppressor mutations
J.Mol.Biol., 385, 2009
3D06
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BU of 3d06 by Molmil
Human p53 core domain with hot spot mutation R249S (I)
分子名称: Cellular tumor antigen p53, ZINC ION
著者Rozenberg, H, Suad, O, Shimon, L.J.W, Frolow, F, Shakked, Z.
登録日2008-05-01
公開日2009-01-20
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structural basis of restoring sequence-specific DNA binding and transactivation to mutant p53 by suppressor mutations
J.Mol.Biol., 385, 2009
3GLI
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BU of 3gli by Molmil
Crystal Structure of the E. coli clamp loader bound to Primer-Template DNA and Psi Peptide
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (5'-D(*CP*TP*GP*GP*CP*CP*TP*AP*TP*A)-3'), ...
著者Simonetta, K.R, Cantor, A.J, Kuriyan, J.
登録日2009-03-12
公開日2009-05-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献The mechanism of ATP-dependent primer-template recognition by a clamp loader complex.
Cell(Cambridge,Mass.), 137, 2009
5LD2
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BU of 5ld2 by Molmil
Cryo-EM structure of RecBCD+DNA complex revealing activated nuclease domain
分子名称: Fork-Hairpin DNA (70-MER), MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Wilkinson, M, Chaban, Y, Wigley, D.B.
登録日2016-06-23
公開日2016-10-05
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.83 Å)
主引用文献Mechanism for nuclease regulation in RecBCD.
Elife, 5, 2016
7R1Q
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BU of 7r1q by Molmil
X-ray structure of the adduct formed upon reaction of the gold(I) N-heterocyclic carbene complex Au2 with lysozyme
分子名称: DIMETHYL SULFOXIDE, GOLD ION, Lysozyme
著者Merlino, A, Ferraro, G.
登録日2022-02-03
公開日2022-07-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Halo complexes of gold(I) containing glycoconjugate carbene ligands: synthesis, characterization, cytotoxicity and interaction with proteins and DNA model systems.
Dalton Trans, 51, 2022
7R1P
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BU of 7r1p by Molmil
X-ray structure of the adduct formed upon reaction of the gold(I) N-heterocyclic carbene complex Au1 with RNase A
分子名称: GOLD ION, Ribonuclease pancreatic, SULFATE ION
著者Merlino, A, Ferraro, G.
登録日2022-02-03
公開日2022-07-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Halo complexes of gold(I) containing glycoconjugate carbene ligands: synthesis, characterization, cytotoxicity and interaction with proteins and DNA model systems.
Dalton Trans, 51, 2022
6LMH
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BU of 6lmh by Molmil
Structure of an ASFV-derived histone-like protein pA104R
分子名称: pA104R
著者Wang, H, Qi, J, Chai, Y, Gao, F.
登録日2019-12-25
公開日2020-05-13
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.805 Å)
主引用文献The structural basis of African swine fever virus pA104R binding to DNA and its inhibition by stilbene derivatives.
Proc.Natl.Acad.Sci.USA, 117, 2020
7SS5
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BU of 7ss5 by Molmil
Activated SgrAI endonuclease DNA-bound dimer with Ca2+ and intact primary site DNA
分子名称: CALCIUM ION, DNA (5'-D(P*GP*GP*TP*CP*TP*TP*CP*AP*CP*AP*CP*CP*GP*GP*TP*GP*TP*GP*AP*AP*GP*AP*CP*C)-3'), SgraIR restriction enzyme
著者Shan, Z, Lyumkis, D, Horton, N.C.
登録日2021-11-09
公開日2021-12-01
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Pretransition state and apo structures of the filament-forming enzyme SgrAI elucidate mechanisms of activation and substrate specificity.
J.Biol.Chem., 298, 2022
7AXZ
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BU of 7axz by Molmil
Ku70/80 complex apo form
分子名称: X-ray repair cross-complementing protein 5, X-ray repair cross-complementing protein 6
著者Hnizda, A, Tesina, P, Novak, P, Blundell, T.L.
登録日2020-11-10
公開日2021-02-10
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献SAP domain forms a flexible part of DNA aperture in Ku70/80.
Febs J., 288, 2021
4ZN3
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BU of 4zn3 by Molmil
Crystal Structure of MjSpt4:Spt5 complex conformation B
分子名称: FE (III) ION, GLYCEROL, Transcription elongation factor Spt4, ...
著者Guo, G.R, Zhou, H.H, Gao, Y.X, Zhu, Z.L, Niu, L.W, Teng, M.K.
登録日2015-05-04
公開日2016-03-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and biochemical insights into the DNA-binding mode of MjSpt4p:Spt5 complex at the exit tunnel of RNAPII
J.Struct.Biol., 192, 2015
2KJC
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BU of 2kjc by Molmil
Solution structure of CzrA in the Zn(II) state
分子名称: CzrA protein
著者Arunkumar, A.I, Campanello, G.C, Giedroc, D.P.
登録日2009-05-27
公開日2009-11-10
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of a paradigm ArsR family zinc sensor in the DNA-bound state
Proc.Natl.Acad.Sci.USA, 106, 2009
3CBB
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BU of 3cbb by Molmil
Crystal Structure of Hepatocyte Nuclear Factor 4alpha in complex with DNA: Diabetes Gene Product
分子名称: Hepatocyte Nuclear Factor 4-alpha promoter element DNA, Hepatocyte Nuclear Factor 4-alpha, DNA binding domain, ...
著者Lu, P, Rha, G.B, Melikishvili, M, Adkins, B.C, Fried, M.G, Chi, Y.I.
登録日2008-02-21
公開日2008-10-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of natural promoter recognition by a unique nuclear receptor, HNF4alpha. Diabetes gene product.
J.Biol.Chem., 283, 2008
4FJO
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BU of 4fjo by Molmil
Structure of the Rev1 CTD-Rev3/7-Pol kappa RIR complex
分子名称: DNA polymerase kappa, DNA polymerase zeta catalytic subunit, DNA repair protein REV1, ...
著者Wojtaszek, J, Lee, C.-J, Zhou, P.
登録日2012-06-11
公開日2012-08-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.718 Å)
主引用文献Structural basis of Rev1-mediated assembly of a quaternary vertebrate translesion polymerase complex consisting of Rev1, heterodimeric Pol zeta and Pol kappa
J.Biol.Chem., 287, 2012
3MKL
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BU of 3mkl by Molmil
Crystal structure of DNA-binding transcriptional dual regulator from Escherichia coli K-12
分子名称: HTH-type transcriptional regulator gadX
著者Chang, C, Mack, J, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2010-04-15
公開日2010-04-28
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structure of DNA-binding transcriptional dual regulator from Escherichia coli K-12
To be Published
6XNY
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BU of 6xny by Molmil
Structure of RAG1 (R848M/E649V)-RAG2-DNA Strand Transfer Complex (Paired-Form)
分子名称: 12RSS integration strand (55-mer), 12RSS signal DNA top strand (34-mer), 23RSS integration strand (66-mer), ...
著者Zhang, Y, Corbett, E, Wu, S, Schatz, D.G.
登録日2020-07-05
公開日2020-08-26
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis for the activation and suppression of transposition during evolution of the RAG recombinase.
Embo J., 39, 2020
5NG6
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BU of 5ng6 by Molmil
Crystal structure of FnCas12a bound to a crRNA
分子名称: CRISPR-associated endonuclease Cpf1, MAGNESIUM ION, crRNA
著者Swarts, D.C, van der Oost, J, Jinek, M.
登録日2017-03-16
公開日2017-06-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.342 Å)
主引用文献Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12a.
Mol. Cell, 66, 2017
3P7N
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BU of 3p7n by Molmil
Crystal structure of light activated transcription factor El222 from Erythrobacter litoralis
分子名称: FLAVIN MONONUCLEOTIDE, Sensor histidine kinase
著者McNulty, R, Luecke, H.
登録日2010-10-12
公開日2011-05-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis of photosensitivity in a bacterial light-oxygen-voltage/helix-turn-helix (LOV-HTH) DNA-binding protein.
Proc.Natl.Acad.Sci.USA, 108, 2011
3GCC
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BU of 3gcc by Molmil
SOLUTION STRUCTURE OF THE GCC-BOX BINDING DOMAIN, NMR, 46 STRUCTURES
分子名称: ATERF1
著者Allen, M.D, Yamasaki, K, Ohme-Takagi, M, Tateno, M, Suzuki, M.
登録日1998-03-13
公開日1999-03-23
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A novel mode of DNA recognition by a beta-sheet revealed by the solution structure of the GCC-box binding domain in complex with DNA.
EMBO J., 17, 1998
6XNZ
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BU of 6xnz by Molmil
Structure of RAG1 (R848M/E649V)-RAG2-DNA Target Capture Complex
分子名称: 12RSS integration strand (34-mer), 12RSS non-integration strand (34-mer), 23RSS integration strand (45-mer), ...
著者Zhang, Y, Corbett, E, Wu, S, Schatz, D.G.
登録日2020-07-05
公開日2020-08-26
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural basis for the activation and suppression of transposition during evolution of the RAG recombinase.
Embo J., 39, 2020
4U82
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BU of 4u82 by Molmil
Structure of S. aureus undecaprenyl diphosphate synthase in complex with FSPP and sulfate
分子名称: Isoprenyl transferase, MAGNESIUM ION, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE, ...
著者Zhu, W, Oldfield, E.
登録日2014-07-31
公開日2015-02-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Antibacterial drug leads: DNA and enzyme multitargeting.
J.Med.Chem., 58, 2015
4GFL
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BU of 4gfl by Molmil
NO mechanism, slma
分子名称: Nucleoid occlusion factor SlmA
著者Schumacher, M.A.
登録日2012-08-03
公開日2013-06-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献SlmA forms a higher-order structure on DNA that inhibits cytokinetic Z-ring formation over the nucleoid.
Proc.Natl.Acad.Sci.USA, 110, 2013
5YIW
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BU of 5yiw by Molmil
Caulobacter crescentus GcrA DNA-binding domain (DBD) in complex with methylated dsDNA (crystal form 2)
分子名称: (R,R)-2,3-BUTANEDIOL, Cell cycle regulatory protein GcrA, DNA (5'-D(*CP*CP*CP*TP*GP*(6MA)P*TP*TP*CP*GP*C)-3'), ...
著者Wu, X, Zhang, Y.
登録日2017-10-06
公開日2018-03-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.551 Å)
主引用文献Structural insights into the unique mechanism of transcription activation by Caulobacter crescentus GcrA.
Nucleic Acids Res., 46, 2018
5YIV
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BU of 5yiv by Molmil
Caulobacter crescentus GcrA DNA-binding domain(DBD) in complex with methylated dsDNA(crystal form 1)
分子名称: Cell cycle regulatory protein GcrA, DNA (5'-D(*CP*CP*GP*(6MA)P*AP*TP*CP*AP*G)-3'), DNA (5'-D(*CP*CP*TP*GP*(6MA)P*TP*TP*CP*G)-3')
著者Wu, X, Zhang, Y.
登録日2017-10-06
公開日2018-03-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.914 Å)
主引用文献Structural insights into the unique mechanism of transcription activation by Caulobacter crescentus GcrA.
Nucleic Acids Res., 46, 2018

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件を2024-09-04に公開中

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