3CBB
Crystal Structure of Hepatocyte Nuclear Factor 4alpha in complex with DNA: Diabetes Gene Product
Summary for 3CBB
Entry DOI | 10.2210/pdb3cbb/pdb |
Descriptor | Hepatocyte Nuclear Factor 4-alpha promoter element DNA, Hepatocyte Nuclear Factor 4-alpha, DNA binding domain, ZINC ION, ... (5 entities in total) |
Functional Keywords | zinc finger, protein-dna complex, diabetes, transcription-dna complex, transcription/dna |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: P41235 |
Total number of polymer chains | 4 |
Total formula weight | 31260.15 |
Authors | Lu, P.,Rha, G.B.,Melikishvili, M.,Adkins, B.C.,Fried, M.G.,Chi, Y.I. (deposition date: 2008-02-21, release date: 2008-10-07, Last modification date: 2024-02-21) |
Primary citation | Lu, P.,Rha, G.B.,Melikishvili, M.,Wu, G.,Adkins, B.C.,Fried, M.G.,Chi, Y.I. Structural basis of natural promoter recognition by a unique nuclear receptor, HNF4alpha. Diabetes gene product. J.Biol.Chem., 283:33685-33697, 2008 Cited by PubMed: 18829458DOI: 10.1074/jbc.M806213200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
Download full validation report