PDB: 36840 件ウェブページステータス検索Chemie searchBIRD

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2OHT	X-ray crystal structure of beta secretase complexed with compound 7 分子名称: Beta-secretase 1, DIMETHYL SULFOXIDE, IODIDE ION, ... 著者 Patel, S. 登録日 2007-01-10 公開日 2007-03-13 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Application of fragment screening by X-ray crystallography to the discovery of aminopyridines as inhibitors of beta-secretase. J.Med.Chem., 50, 2007
2HAH	The structure of FIV 12S protease in complex with TL-3 分子名称: Protease, benzyl [(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-dibenzyl-8,9-dihydroxy-1,16-dimethyl-4,13-bis(1-methylethyl)-2,5,12,15,18-pentaoxo-20-phenyl-19-oxa-3,6,11,14,17-pentaazaicos-1-yl]carbamate 著者 Heaslet, H, Lin, Y.C, Elder, J.H, Stout, C.D. 登録日 2006-06-12 公開日 2007-02-13 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of an FIV/HIV chimeric protease complexed with the broad-based inhibitor, TL-3. Retrovirology, 4, 2007
2OJI	Crystal structure of ERK2 in complex with N-benzyl-4-(4-(3-chlorophenyl)-1H-pyrazol-3-yl)-1H-pyrrole-2-carboxamide 分子名称: Mitogen-activated protein kinase 1, N-BENZYL-4-[4-(3-CHLOROPHENYL)-1H-PYRAZOL-3-YL]-1H-PYRROLE-2-CARBOXAMIDE, SULFATE ION 著者 Xie, X, Jacobs, M.D. 登録日 2007-01-12 公開日 2007-02-06 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Flipped Out: Structure-Guided Design of Selective Pyrazolylpyrrole ERK Inhibitors. J.Med.Chem., 50, 2007
2OK1	Crystal structure of JNK3 bound to N-benzyl-4-(4-(3-chlorophenyl)-1H-pyrazol-3-yl)-1H-pyrrole-2-carboxamide 分子名称: Mitogen-activated protein kinase 10, N-BENZYL-4-[4-(3-CHLOROPHENYL)-1H-PYRAZOL-3-YL]-1H-PYRROLE-2-CARBOXAMIDE 著者 Xie, X, Jacobs, M.D. 登録日 2007-01-15 公開日 2007-02-06 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Flipped Out: Structure-Guided Design of Selective Pyrazolylpyrrole ERK Inhibitors. J.Med.Chem., 50, 2007
2HED	CONTRIBUTION OF WATER MOLECULES IN THE INTERIOR OF A PROTEIN TO THE CONFORMATIONAL STABILITY 分子名称: LYSOZYME, SODIUM ION 著者 Takano, K, Funahashi, J, Yamagata, Y, Fujii, S, Yutani, K. 登録日 1997-09-16 公開日 1998-01-14 最終更新日 2021-11-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Contribution of water molecules in the interior of a protein to the conformational stability. J.Mol.Biol., 274, 1997
2OMG	Structure of human insulin cocrystallized with protamine and urea 分子名称: CHLORIDE ION, FORMAMIDE, Insulin A chain, ... 著者 Norrman, M, Schluckebier, G. 登録日 2007-01-22 公開日 2007-03-27 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 Structural characterization of insulin NPH formulations. EUR.J.PHARM.SCI., 30, 2007
2ONL	Crystal Structure of the p38a-MAPKAP kinase 2 Heterodimer 分子名称: MAP kinase-activated protein kinase 2, Mitogen-activated protein kinase 14 著者 Ter Haar, E. 登録日 2007-01-24 公開日 2007-02-06 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 Crystal structure of the P38alpha-MAPKAP kinase 2 heterodimer. J.Biol.Chem., 282, 2007
2H73	Crystal Structure of Thioredoxin Mutant D43E in Hexagonal (p61) Space Group 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Thioredoxin 著者 Gavira, J.A, Godoy-Ruiz, R, Ibarra-Molero, B, Sanchez-Ruiz, J.M. 登録日 2006-06-01 公開日 2007-05-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Crystal Structure of Thioredoxin Mutant D43E in Hexagonal (p61) Space Group To be Published
2GNL	PKA threefold mutant model of Rho-kinase with inhibitor H-1152P 分子名称: (S)-2-METHYL-1-[(4-METHYL-5-ISOQUINOLINE)SULFONYL]-HOMOPIPERAZINE, cAMP-dependent protein kinase inhibitor alpha, cAMP-dependent protein kinase, ... 著者 Bonn, S, Herrero, S, Breitenlechner, C.B, Engh, R.A, Gassel, M, Bossemeyer, D. 登録日 2006-04-10 公開日 2006-05-23 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural analysis of protein kinase A mutants with Rho-kinase inhibitor specificity J.Biol.Chem., 281, 2006
2OLG	Crystal structure of the serine protease domain of prophenoloxidase activating factor-I in a zymogen form 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Pro-phenoloxidase activating enzyme-I, ... 著者 Ha, N.C, Piao, S. 登録日 2007-01-19 公開日 2007-02-06 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of the serine protease domain of prophenoloxidase activating factor-I J.Biol.Chem., 282, 2007
2OLI	Crystal structure of the complex formed between a group II phospholipase A2 and an indole derivative at 2.2 A resolution 分子名称: INDOLYLPROPIONIC ACID, Phospholipase A2 VRV-PL-VIIIa 著者 Kumar, S, Singh, N, Sharma, S, Kaur, P, Singh, T.P. 登録日 2007-01-19 公開日 2007-02-13 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Crystal structure of the complex formed between a group II phospholipase A2 and an indole derivative at 2.2 A resolution To be Published
7A4Q	The Crystal structure of RO4613269 bound to CK2alpha 分子名称: 2-methoxyimino-5-(quinolin-6-ylmethyl)-1,3-thiazol-4-one, Casein kinase II subunit alpha 著者 Brear, P, Hyvonen, M. 登録日 2020-08-20 公開日 2022-06-08 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Chemical proteomics reveals the target landscape of 1,000 kinase inhibitors. Nat.Chem.Biol., 2023
2GQX	Crystal structure of cytochrome p450cam mutant (f87w/y96f/l244a/v247l/c334a) with pentachlorobenzene 分子名称: 1,2,3,4,5-PENTACHLOROBENZENE, Cytochrome P450-cam, POTASSIUM ION, ... 著者 Rao, Z, Wong, L.L, Xu, F, Bell, S.G. 登録日 2006-04-22 公開日 2007-04-17 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure-activity correlations in pentachlorobenzene oxidation by engineered cytochrome P450cam Protein Eng.Des.Sel., 20, 2007
2OLZ	Structure of human insulin in presence of thiocyanate at pH 7.0 分子名称: GLYCEROL, Insulin A, Insulin B, ... 著者 Norrman, M, Schluckebier, G. 登録日 2007-01-20 公開日 2007-12-04 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystallographic characterization of two novel crystal forms of human insulin induced by chaotropic agents and a shift in pH. Bmc Struct.Biol., 7, 2007
2GWK	SpvB ADP-ribosylated actin: orthorhombic crystal form 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... 著者 Stebbins, C.E, Margarit, S.M. 登録日 2006-05-04 公開日 2006-08-29 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A steric antagonism of actin polymerization by a salmonella virulence protein. Structure, 14, 2006
2OQU	High Pressure Cryocooling of Capillary Sample Cryoprotection and Diffraction Phasing at Long Wavelengths 分子名称: CALCIUM ION, Elastase-1, SULFATE ION, ... 著者 Kim, C.U, Hao, Q, Gruner, S.M. 登録日 2007-02-01 公開日 2007-05-01 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 High-pressure cryocooling for capillary sample cryoprotection and diffraction phasing at long wavelengths. Acta Crystallogr.,Sect.D, 63, 2007
2GZY	solution structures of the reduced form of thioredoxin from Bacillus subtilis 分子名称: Thioredoxin 著者 Xu, H, Zhang, X, Chen, J, Jin, C. 登録日 2006-05-12 公開日 2007-02-13 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Conformational fluctuations coupled to the thiol-disulfide transfer between thioredoxin and arsenate reductase in Bacillus subtilis. J.Biol.Chem., 282, 2007
4J53	Crystal structure of PLK1 in complex with TAK-960 分子名称: 4-[(9-cyclopentyl-7,7-difluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-2-fluoro-5-methoxy-N-(1-methylpiperidin-4-yl)benzamide, ACETATE ION, Serine/threonine-protein kinase PLK1, ... 著者 Hosfield, D.J, Skene, R.J. 登録日 2013-02-07 公開日 2013-05-29 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Discovery of TAK-960: An orally available small molecule inhibitor of polo-like kinase 1 (PLK1). Bioorg.Med.Chem.Lett., 23, 2013
2GV5	crystal structure of Sfi1p/Cdc31p complex 分子名称: Cell division control protein 31, Sfi1p 著者 Li, S, Sandercock, A.M, Conduit, P.T, Robinson, C.V, Williams, R.L, Kilmartin, J.V. 登録日 2006-05-02 公開日 2006-06-27 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural role of Sfi1p-centrin filaments in budding yeast spindle pole body duplication. J.Cell Biol., 173, 2006
2GWJ	SpvB ADP-ribosylated actin: hexagonal crystal form 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... 著者 Stebbins, C.E, Margarit, S.M. 登録日 2006-05-04 公開日 2006-08-29 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A steric antagonism of actin polymerization by a salmonella virulence protein. Structure, 14, 2006
2OLP	Structure and ligand selection of hemoglobin II from Lucina pectinata 分子名称: Hemoglobin II, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Gavira, J.A, Camara-Artigas, A, de Jesus, W, Lopez-Garriga, J, Garcia-Ruiz, J.M. 登録日 2007-01-19 公開日 2007-12-18 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.932 Å) 主引用文献 Structure and Ligand Selection of Hemoglobin II from Lucina pectinata J.Biol.Chem., 283, 2008
2OM0	Structure of human insulin in presence of urea at pH 6.5 分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ... 著者 Norrman, M, Schluckebier, G. 登録日 2007-01-20 公開日 2007-12-04 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Crystallographic characterization of two novel crystal forms of human insulin induced by chaotropic agents and a shift in pH. Bmc Struct.Biol., 7, 2007
2OMU	Crystal structure of InlA G194S+S Y369S/hEC1 complex 分子名称: CALCIUM ION, CHLORIDE ION, Epithelial-cadherin, ... 著者 Wollert, T, Heinz, D.W, Schubert, W.D. 登録日 2007-01-23 公開日 2007-08-28 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Thermodynamically reengineering the listerial invasion complex InlA/E-cadherin. Proc.Natl.Acad.Sci.Usa, 104, 2007
4J8M	Aurora A in complex with CD532 分子名称: 1,2-ETHANEDIOL, 1-[4-[[4-[(5-cyclopentyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]amino]phenyl]-3-[3-(trifluoromethyl)phenyl]urea, Aurora kinase A, ... 著者 Meyerowitz, J.G, Gustafson, W.C, Shokat, K.M, Weiss, W.A. 登録日 2013-02-14 公開日 2014-09-10 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (1.853 Å) 主引用文献 Drugging MYCN through an Allosteric Transition in Aurora Kinase A. Cancer Cell, 26, 2014
2H6Z	Crystal Structure of Thioredoxin Mutant E44D in Hexagonal (p61) Space Group 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Thioredoxin 著者 Gavira, J.A, Godoy-Ruiz, R, Ibarra-Molero, B, Sanchez-Ruiz, J.M. 登録日 2006-06-01 公開日 2007-05-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 A stability pattern of protein hydrophobic mutations that reflects evolutionary structural optimization. Biophys.J., 89, 2005

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