2OK1

Crystal structure of JNK3 bound to N-benzyl-4-(4-(3-chlorophenyl)-1H-pyrazol-3-yl)-1H-pyrrole-2-carboxamide

Summary for 2OK1

Entry DOI	10.2210/pdb2ok1/pdb
Related	2OJG 2OJI 2OJJ
Descriptor	Mitogen-activated protein kinase 10, N-BENZYL-4-[4-(3-CHLOROPHENYL)-1H-PYRAZOL-3-YL]-1H-PYRROLE-2-CARBOXAMIDE (3 entities in total)
Functional Keywords	kinase inhibitor, transferase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm : P53779
Total number of polymer chains	1
Total formula weight	42493.57
Authors	Xie, X.,Jacobs, M.D. (deposition date: 2007-01-15, release date: 2007-02-06, Last modification date: 2023-12-27)
Primary citation	Aronov, A.M.,Baker, C.,Bemis, G.W.,Cao, J.,Chen, G.,Ford, P.J.,Germann, U.A.,Green, J.,Hale, M.R.,Jacobs, M.,Janetka, J.W.,Maltais, F.,Martinez-Botella, G.,Namchuk, M.N.,Straub, J.,Tang, Q.,Xie, X. Flipped Out: Structure-Guided Design of Selective Pyrazolylpyrrole ERK Inhibitors. J.Med.Chem., 50:1280-1287, 2007 Cited by PubMed: 17300186 DOI: 10.1021/jm061381f PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation