3EVE
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3EVF
| Crystal structure of Me7-GpppA complex of yellow fever virus methyltransferase and S-adenosyl-L-homocysteine | 分子名称: | P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, RNA-directed RNA polymerase NS5, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Thompson, A.A, Geiss, B.J, Peersen, O.B. | 登録日 | 2008-10-13 | 公開日 | 2009-01-06 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Analysis of flavivirus NS5 methyltransferase cap binding. J.Mol.Biol., 385, 2009
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7EGF
| TFIID lobe A subcomplex | 分子名称: | TATA-box-binding protein, Transcription initiation factor TFIID subunit 10, Transcription initiation factor TFIID subunit 11, ... | 著者 | Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y. | 登録日 | 2021-03-24 | 公開日 | 2021-05-05 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.16 Å) | 主引用文献 | Structural insights into preinitiation complex assembly on core promoters. Science, 2021
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7V2Y
| cryo-EM structure of yeast THO complex with Sub2 | 分子名称: | ATP-dependent RNA helicase SUB2, Protein TEX1, THO complex subunit 2, ... | 著者 | Chen, C, Tan, M, Wu, Z, Wu, J, Lei, M. | 登録日 | 2021-08-10 | 公開日 | 2022-07-27 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural and functional insights into R-loop prevention and mRNA export by budding yeast THO-Sub2 complex. Sci Bull (Beijing), 66, 2021
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3EVC
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3EVD
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3MAG
| VACCINIA METHYLTRANSFERASE VP39 COMPLEXED WITH M3ADE AND S-ADENOSYLHOMOCYSTEINE | 分子名称: | 6-AMINO-3-METHYLPURINE, S-ADENOSYL-L-HOMOCYSTEINE, VP39 | 著者 | Hu, G, Hodel, A.E, Gershon, P.D, Quiocho, F.A. | 登録日 | 1998-07-12 | 公開日 | 1999-07-22 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | mRNA cap recognition: dominant role of enhanced stacking interactions between methylated bases and protein aromatic side chains. Proc.Natl.Acad.Sci.USA, 96, 1999
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3O0F
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8G1P
| Co-crystal structure of Compound 11 in complex with the bromodomain of human SMARCA2 and pVHL:ElonginC:ElonginB | 分子名称: | (2~{S},4~{R})-~{N}-[[2-[2-[4-[[4-[3-azanyl-6-(2-hydroxyphenyl)pyridazin-4-yl]piperazin-1-yl]methyl]phenyl]ethoxy]-4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-1-[(2~{S})-2-[(1-fluoranylcyclopropyl)carbonylamino]-3,3-dimethyl-butanoyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Elongin-B, Elongin-C, ... | 著者 | Ghimire Rijal, S, Wurz, R.P, Vaish, A. | 登録日 | 2023-02-02 | 公開日 | 2023-07-26 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Affinity and cooperativity modulate ternary complex formation to drive targeted protein degradation. Nat Commun, 14, 2023
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3BEP
| Structure of a sliding clamp on DNA | 分子名称: | 1-(3-hydroxypropyl)-2-{(1E,3E,5E)-5-[1-(3-hydroxypropyl)-3,3-dimethyl-1,3-dihydro-2H-indol-2-ylidene]penta-1,3-dien-1-y l}-3,3-dimethyl-3H-indolium, DNA (5'-D(*DTP*DTP*DTP*DTP*DAP*DTP*DAP*DCP*DGP*DAP*DTP*DGP*DGP*DG)-3'), DNA (5'-D(P*DCP*DCP*DCP*DAP*DTP*DCP*DGP*DTP*DAP*DT)-3'), ... | 著者 | Georgescu, R.E, Kim, S.S, Yurieva, O, Kuriyan, J, Kong, X.-P, O'Donnell, M. | 登録日 | 2007-11-19 | 公開日 | 2008-01-29 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Structure of a sliding clamp on DNA Cell(Cambridge,Mass.), 132, 2008
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3MCT
| VACCINIA METHYLTRANSFERASE VP39 COMPLEXED WITH M3CYT AND S-ADENOSYLHOMOCYSTEINE | 分子名称: | 3-METHYLCYTOSINE, S-ADENOSYL-L-HOMOCYSTEINE, VP39 | 著者 | Hu, G, Gershon, P.D, Hodel, A.E, Quiocho, F.A. | 登録日 | 1999-01-05 | 公開日 | 1999-07-22 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | mRNA cap recognition: dominant role of enhanced stacking interactions between methylated bases and protein aromatic side chains. Proc.Natl.Acad.Sci.USA, 96, 1999
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8RNH
| Crystal structure of HLA B*18:01 in complex with EEIEITTHF, an 9-mer epitope from Influenza A | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | 著者 | Murdolo, L.D, Maddumaage, J, Gras, S. | 登録日 | 2024-01-10 | 公開日 | 2024-05-08 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Characterisation of novel influenza-derived HLA-B*18:01-restricted epitopes. Clin Transl Immunology, 13, 2024
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8G7U
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8G7T
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8G7V
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8PTG
| Structure of the transcription termination factor Rho bound to RNA at the PBS and SBS | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | 著者 | Said, N, Hilal, T, Wahl, M.C. | 登録日 | 2023-07-14 | 公開日 | 2024-04-17 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Sm-like protein Rof inhibits transcription termination factor rho by binding site obstruction and conformational insulation. Nat Commun, 15, 2024
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6EIH
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8VRK
| Rigid body fitted model for refined density map of gamma tubulin ring complex capped microtubule | 分子名称: | Actin, cytoplasmic 1, Gamma-tubulin complex component 3, ... | 著者 | Aher, A, Urnavicius, L, Kapoor, T.M. | 登録日 | 2024-01-22 | 公開日 | 2024-03-27 | 最終更新日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (8.5 Å) | 主引用文献 | Structure of the gamma-tubulin ring complex-capped microtubule. Nat.Struct.Mol.Biol., 31, 2024
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8VRJ
| Rigid body fitted model for gamma tubulin ring complex capped microtubule | 分子名称: | Actin, cytoplasmic 1, Gamma-tubulin complex component 3, ... | 著者 | Aher, A, Urnavicius, L, Kapoor, T.M. | 登録日 | 2024-01-22 | 公開日 | 2024-03-27 | 最終更新日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (7.7 Å) | 主引用文献 | Structure of the gamma-tubulin ring complex-capped microtubule. Nat.Struct.Mol.Biol., 31, 2024
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3BBF
| Crystal structure of the NM23-H2 transcription factor complex with GDP | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Weichsel, A, Montfort, W.R. | 登録日 | 2007-11-09 | 公開日 | 2008-09-23 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | NM23-H2 may play an indirect role in transcriptional activation of c-myc gene expression but does not cleave the nuclease hypersensitive element III1. Mol.Cancer Ther., 8, 2009
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1BKY
| VACCINIA METHYLTRANSFERASE VP39 COMPLEXED WITH M1CYT AND S-ADENOSYLHOMOCYSTEINE | 分子名称: | 1-METHYLCYTOSINE, S-ADENOSYL-L-HOMOCYSTEINE, VP39 | 著者 | Hu, G, Hodel, A.E, Gershon, P.D, Quiocho, F.A. | 登録日 | 1998-07-13 | 公開日 | 1999-07-22 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | mRNA cap recognition: dominant role of enhanced stacking interactions between methylated bases and protein aromatic side chains. Proc.Natl.Acad.Sci.USA, 96, 1999
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3BBB
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3BBC
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6ZHC
| PROTAC6 mediated complex of VHL:EloB:EloC and Bcl-xL | 分子名称: | 1,2-ETHANEDIOL, 2-[8-(1,3-benzothiazol-2-ylcarbamoyl)-3,4-dihydro-1~{H}-isoquinolin-2-yl]-5-[3-[4-[3-[2-[2-[2-[2-[2-[3-[[(2~{S})-3,3-dimethyl-1-[(2~{S},4~{R})-2-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methylcarbamoyl]-4-oxidanyl-pyrrolidin-1-yl]-1-oxidanylidene-butan-2-yl]amino]-3-oxidanylidene-propoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]prop-1-ynyl]phenoxy]propyl]-1,3-thiazole-4-carboxylic acid, Bcl-2-like protein 1, ... | 著者 | Chung, C. | 登録日 | 2020-06-22 | 公開日 | 2020-08-05 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Structural Insights into PROTAC-Mediated Degradation of Bcl-xL. Acs Chem.Biol., 15, 2020
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4L81
| Structure of the SAM-I/IV riboswitch (env87(deltaU92, deltaG93)) | 分子名称: | COBALT HEXAMMINE(III), MAGNESIUM ION, S-ADENOSYLMETHIONINE, ... | 著者 | Trausch, J.J, Reyes, F.E, Edwards, A.L, Batey, R.T. | 登録日 | 2013-06-15 | 公開日 | 2014-05-28 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Structural basis for diversity in the SAM clan of riboswitches. Proc.Natl.Acad.Sci.USA, 111, 2014
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