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1M7D
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Crystal structure of a Monoclonal Fab Specific for Shigella flexneri Y Lipopolysaccharide complexed with a trisaccharide
分子名称: alpha-L-rhamnopyranose-(1-3)-alpha-L-Olivopyranose-(1-3)-methyl 2-acetamido-2-deoxy-beta-D-glucopyranoside, heavy chain of the monoclonal antibody Fab SYA/J6, light chain of the monoclonal antibody Fab SYA/J6
著者Vyas, N.K, Vyas, M.N, Chervenak, M.C, Johnson, M.A, Pinto, B.M, Bundle, D.R, Quiocho, F.A.
登録日2002-07-19
公開日2003-07-22
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular Recognition of Oligosaccharide Epitopes by a Monoclonal Fab Specific for Shigella flexneri Y Lipopolysaccharide: X-ray Structures and Thermodynamics
Biochemistry, 41, 2002
1MCL
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PRINCIPLES AND PITFALLS in DESIGNING SITE DIRECTED PEPTIDE LIGANDS
分子名称: IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN), N-ACETYL-D-HIS-L-PRO-OH
著者Edmundson, A.B, Harris, D.L, Fan, Z.-C, Guddat, L.W.
登録日1993-02-25
公開日1994-01-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Principles and pitfalls in designing site-directed peptide ligands.
Proteins, 16, 1993
1MCE
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PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS
分子名称: Immunoglobulin lambda-1 light chain, PEPTIDE N-ACETYL-L-GLN-D-PHE-L-HIS-D-PRO-B-ALA-OH
著者Edmundson, A.B, Harris, D.L, Fan, Z.-C, Guddat, L.W.
登録日1993-02-25
公開日1994-01-31
最終更新日2022-04-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Principles and pitfalls in designing site-directed peptide ligands.
Proteins, 16, 1993
1M71
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Crystal structure of a Monoclonal Fab Specific for Shigella Flexneri Y lipopolysaccharide
分子名称: heavy chain of the monoclonal antibody Fab SYA/J6, light chain of the monoclonal antibody Fab SYA/J6
著者Vyas, N.K, Vyas, M.N, Chervenak, M.C, Johnson, M.A, Pinto, B.M, Bundle, D.R, Quiocho, F.A.
登録日2002-07-18
公開日2003-07-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Molecular Recognition of Oligosaccharide Epitopes by a Monoclonal Fab Specific for Shigella flexneri Y Lipopolysaccharide: X-ray Structures and Thermodyanamics
Biochemistry, 41, 2002
1MNU
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UNLIGANDED BACTERICIDAL ANTIBODY AGAINST NEISSERIA MENINGITIDIS
分子名称: CADMIUM ION, PROTEIN (IGG2A-KAPPA ANTIBODY MN12H2 (HEAVY CHAIN)), PROTEIN (IGG2A-KAPPA ANTIBODY MN12H2 (LIGHT CHAIN))
著者Van Den Elsen, J, Vandeputte-Rutten, L, Kroon, J, Gros, P.
登録日1999-04-30
公開日1999-05-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Bactericidal antibody recognition of meningococcal PorA by induced fit. Comparison of liganded and unliganded Fab structures.
J.Biol.Chem., 274, 1999
1MCD
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BU of 1mcd by Molmil
PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS
分子名称: Immunoglobulin lambda-1 light chain, PEPTIDE N-ACETYL-D-PHE-B-ALA-L-HIS-D-PRO-NH2
著者Edmundson, A.B, Harris, D.L, Fan, Z.-C, Guddat, L.W.
登録日1993-02-25
公開日1994-01-31
最終更新日2020-03-04
実験手法X-RAY DIFFRACTION
主引用文献Principles and pitfalls in designing site-directed peptide ligands.
Proteins, 16, 1993
1MCF
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BU of 1mcf by Molmil
PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS
分子名称: Immunoglobulin lambda-1 light chain, PEPTIDE N-ACETYL-L-GLN-D-PHE-L-HIS-D-PRO-B-ALA-B-ALA-OH
著者Edmundson, A.B, Harris, D.L, Fan, Z.-C, Guddat, L.W.
登録日1993-02-25
公開日1994-01-31
最終更新日2022-04-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Principles and pitfalls in designing site-directed peptide ligands.
Proteins, 16, 1993
4W4O
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BU of 4w4o by Molmil
High-resolution crystal structure of Fc bound to its human receptor Fc-gamma-RI
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, GLYCEROL, ...
著者Caaveiro, J.M.M, Kiyoshi, M, Tsumoto, K.
登録日2014-08-15
公開日2015-04-29
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for binding of human IgG1 to its high-affinity human receptor Fc gamma RI
Nat Commun, 6, 2015
1W72
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Crystal structure of HLA-A1:MAGE-A1 in complex with Fab-Hyb3
分子名称: BETA-2-MICROGLOBULIN, GLYCEROL, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ...
著者Hulsmeyer, M, Chames, P, Hillig, R.C, Stanfield, R.L, Held, G, Coulie, P.G, Alings, C, Wille, G, Saenger, W, Uchanska-Ziegler, B, Hoogenboom, H.R, Ziegler, A.
登録日2004-08-27
公開日2004-11-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献A Major Histocompatibility Complex.Peptide- Restricted Antibody and T Cell Receptor Molecules Recognize Their Target by Distinct Binding Modes: Crystal Structure of Human Leukocyte Antigen (Hla)-A1.Mage-A1 in Complex with Fab-Hyb3
J.Biol.Chem., 280, 2005
2XFX
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cattle MHC class I N01301 presenting an 11mer from Theileria parva
分子名称: BETA-2-MICROGLOBULIN, MHC CLASS 1, UNCHARACTERIZED PROTEIN
著者Macdonald, I.K, Harkiolaki, M, Hunt, L, Morrison, W.I, Connelley, T, Graham, S.P, Jones, E.Y, Flower, D.R, Ellis, S.A.
登録日2010-05-28
公開日2010-10-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mhc Class I Bound to an Immunodominant Theileria Parva Epitope Demonstrates Unconventional Presentation to T Cell Receptors.
Plos Pathog., 6, 2010
2XPG
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BU of 2xpg by Molmil
Crystal structure of a MHC class I-peptide complex
分子名称: BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-3 ALPHA CHAIN, ...
著者McMahon, R.M, Friis, L, Siebold, C, Friese, M.A, Fugger, L, Jones, E.Y.
登録日2010-08-26
公開日2011-04-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of Hla-A0301 in Complex with a Peptide of Proteolipid Protein: Insights Into the Role of Hla-A Alleles in Susceptibility to Multiple Sclerosis
Acta Crystallogr.,Sect.D, 67, 2011
4WDI
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Weak TCR binding to an unstable insulin epitope drives type 1 diabetes
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ...
著者Rizkallah, P.J, Cole, D.K.
登録日2014-09-08
公開日2015-06-24
最終更新日2015-07-01
実験手法X-RAY DIFFRACTION (2.313 Å)
主引用文献Distortion of the Major Histocompatibility Complex Class I Binding Groove to Accommodate an Insulin-derived 10-Mer Peptide.
J.Biol.Chem., 290, 2015
7LLI
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Stimulatory immune receptor protein complex
分子名称: 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, ...
著者Rice, M.T, Littler, D.R, Rossjohn, J, Gully, B.S.
登録日2021-02-04
公開日2021-11-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Recognition of the antigen-presenting molecule MR1 by a V delta 3 + gamma delta T cell receptor.
Proc.Natl.Acad.Sci.USA, 118, 2021
7LLJ
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Inhibitory immune receptor protein complex
分子名称: Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, N-(6-formyl-4-oxo-3,4-dihydropteridin-2-yl)acetamide, ...
著者Rice, M.T, Littler, D.R, Rossjohn, J, Gully, B.S.
登録日2021-02-04
公開日2021-11-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Recognition of the antigen-presenting molecule MR1 by a V delta 3 + gamma delta T cell receptor.
Proc.Natl.Acad.Sci.USA, 118, 2021
4F7P
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Crystal Structure of HLA-A*2402 Complexed with a Newly Identified Peptide from 2009H1N1 PB1 (496-505)
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-24 alpha chain, ...
著者Liu, J, Zhang, S, Tan, S, Yi, Y, Wu, B, Zhu, F, Wang, H, Qi, J, Gao, G.F.
登録日2012-05-16
公開日2012-10-10
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Cross-Allele Cytotoxic T Lymphocyte Responses against 2009 Pandemic H1N1 Influenza A Virus among HLA-A24 and HLA-A3 Supertype-Positive Individuals.
J.Virol., 86, 2012
3UTQ
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Human HLA-A*0201-ALWGPDPAAA
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
著者Rizkallah, P.J, Cole, D.K, Sewell, A.K, Bulek, A.M.
登録日2011-11-26
公開日2012-01-25
最終更新日2012-03-07
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes.
Nat.Immunol., 13, 2012
4F7M
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Crystal Structure of HLA-A*2402 Complexed with a Newly Identified Peptide from 2009 H1N1 PA (649-658)
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-24 alpha chain, ...
著者Liu, J, Zhang, S, Tan, S, Yi, Y, Wu, B, Zhu, F, Wang, H, Qi, J, George, F.G.
登録日2012-05-16
公開日2012-10-10
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Cross-Allele Cytotoxic T Lymphocyte Responses against 2009 Pandemic H1N1 Influenza A Virus among HLA-A24 and HLA-A3 Supertype-Positive Individuals.
J.Virol., 86, 2012
3UTS
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1E6-A*0201-ALWGPDPAAA Complex, Monoclinic
分子名称: 1E6 TCR Alpha Chain, 1E6 TCR Beta Chain, Beta-2-microglobulin, ...
著者Rizkallah, P.J, Cole, D.K, Sewell, A.K, Bulek, A.M.
登録日2011-11-26
公開日2012-01-25
最終更新日2012-03-07
実験手法X-RAY DIFFRACTION (2.712 Å)
主引用文献Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes.
Nat.Immunol., 13, 2012
4FQX
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Crystal structure of HLA-DM bound to HLA-DR1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DM alpha chain, ...
著者Sethi, D.K, Pos, W, Wucherpfennig, K.W.
登録日2012-06-25
公開日2013-01-09
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.599 Å)
主引用文献Crystal Structure of the HLA-DM-HLA-DR1 Complex Defines Mechanisms for Rapid Peptide Selection.
Cell(Cambridge,Mass.), 151, 2012
6Q3S
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BU of 6q3s by Molmil
Engineered Human HLA_A2 MHC Class I molecule in complex with TCR and SV9 peptide
分子名称: ACETATE ION, Beta-2-microglobulin, GLYCEROL, ...
著者Meijers, R, Anjanappa, R, Springer, S, Garcia-Alai, M.
登録日2018-12-04
公開日2019-07-24
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献High-throughput peptide-MHC complex generation and kinetic screenings of TCRs with peptide-receptive HLA-A*02:01 molecules.
Sci Immunol, 4, 2019
4O2E
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A peptide complexed with HLA-B*3901
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-39 alpha chain, ...
著者Sun, M, Liu, J, Qi, J, Tefsen, B, Shi, Y, Yan, J, Gao, G.F.
登録日2013-12-17
公開日2014-07-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.981 Å)
主引用文献N alpha-terminal acetylation for T cell recognition: molecular basis of MHC class I-restricted n alpha-acetylpeptide presentation
J.Immunol., 192, 2014
4O2F
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A peptide complexed with HLA-B*3901
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-39 alpha chain, ...
著者Sun, M, Liu, J, Qi, J, Tefsen, B, Shi, Y, Yan, J, Gao, G.F.
登録日2013-12-17
公開日2014-07-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.901 Å)
主引用文献N alpha-terminal acetylation for T cell recognition: molecular basis of MHC class I-restricted n alpha-acetylpeptide presentation
J.Immunol., 192, 2014
4O5I
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Crystal structure of broadly neutralizing antibody F045-092 in complex with A/Victoria/361/2011 (H3N2) influenza hemagglutinin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab F045-092 heavy chain, ...
著者Lee, P.S, Wilson, I.A.
登録日2013-12-19
公開日2014-04-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (6.501 Å)
主引用文献Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus.
Nat Commun, 5, 2014
6QIP
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Ternary complex of FcRn ectodomain, FcRn binding optimised human serum albumin and the albumin-biniding side chain of the human growth hormone derivative somapacitan
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BETA-MERCAPTOETHANOL, Beta-2-microglobulin, ...
著者Johansson, E.
登録日2019-01-21
公開日2020-02-05
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Identification of Binding Sites on Human Serum Albumin for Somapacitan, a Long-Acting Growth Hormone Derivative.
Biochemistry, 59, 2020
7Q9B
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MHC Class I A02 Allele presenting EAAGIGILTV, in complex with Mel8 TCR
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLU-ALA-ALA-GLY-ILE-GLY-ILE-LEU-THR-VAL, ...
著者Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A.
登録日2021-11-12
公開日2023-02-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.24 Å)
主引用文献Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy.
Cell, 186, 2023

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