6Q3S

Engineered Human HLA_A2 MHC Class I molecule in complex with TCR and SV9 peptide

Summary for 6Q3S

• Entry DOI: 10.2210/pdb6q3s/pdb
• Related: 2BNQ
• Descriptor: HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, SER-LEU-LEU-MET-TRP-ILE-THR-GLN-VAL, ... (8 entities in total)
• Functional Keywords: mhc molecule, engineered disulphide bond, immune system, tcr
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 5
• Total formula weight: 94622.03

Authors

Meijers, R.,Anjanappa, R.,Springer, S.,Garcia-Alai, M. (deposition date: 2018-12-04, release date: 2019-07-24, Last modification date: 2021-02-03)

• Primary citation: Moritz, A.,Anjanappa, R.,Wagner, C.,Bunk, S.,Hofmann, M.,Pszolla, G.,Saikia, A.,Garcia-Alai, M.,Meijers, R.,Rammensee, H.G.,Springer, S.,Maurer, D.; High-throughput peptide-MHC complex generation and kinetic screenings of TCRs with peptide-receptive HLA-A*02:01 molecules.; Sci Immunol, 4:-, 2019; PubMed: 31324691; DOI: 10.1126/sciimmunol.aav0860

Experimental method

X-RAY DIFFRACTION (2.5 Å)