PDB: 2682 件ウェブページステータス検索Chemie searchBIRD

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3PR3	Crystal structure of Plasmodium falciparum glucose-6-phosphate isomerase (PF14_0341) in complex with fructose-6-phosphate 分子名称: 6-O-phosphono-beta-D-fructofuranose, Glucose-6-phosphate isomerase, PHOSPHATE ION 著者 Gileadi, T, Wernimont, A.K, Hutchinson, A, Weadge, J, Cossar, D, Lew, J, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Hui, R, Hills, T, Pizarro, J.C, Structural Genomics Consortium (SGC) 登録日 2010-11-29 公開日 2011-02-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Crystal structure of Plasmodium falciparum glucose-6-phosphate isomerase (PF14_0341) in complex with fructose-6-phosphate To be Published
2SKE	PYRIDOXAL PHOSPHORYLASE B IN COMPLEX WITH PHOSPHITE, GLUCOSE AND INOSINE-5'-MONOPHOSPHATE 分子名称: INOSINIC ACID, PHOSPHITE ION, PYRIDOXAL PHOSPHORYLASE B, ... 著者 Oikonomakos, N.G, Zographos, S.E, Tsitsanou, K.E, Johnson, L.N, Acharya, K.R. 登録日 1998-12-11 公開日 1998-12-16 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.46 Å) 主引用文献 Activator anion binding site in pyridoxal phosphorylase b: the binding of phosphite, phosphate, and fluorophosphate in the crystal. Protein Sci., 5, 1996
8A98	CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : snoRNA MUTANT 分子名称: 40S ribosomal protein S12, 40S ribosomal protein S14, 40S ribosomal protein S19-like protein, ... 著者 Rajan, K.S, Yonath, A, Bashan, A. 登録日 2022-06-28 公開日 2023-10-11 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (2.46 Å) 主引用文献 Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification. Cell Rep, 43, 2024
8OVA	CRYO-EM STRUCTURE OF TRYPANOSOMA BRUCEI PROCYCLIC FORM 80S RIBOSOME : PARENTAL STRAIN 分子名称: 40S ribosomal protein L14, putative, 40S ribosomal protein S10, ... 著者 Rajan, K.S, Yonath, A. 登録日 2023-04-25 公開日 2023-11-29 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.47 Å) 主引用文献 A single pseudouridine on rRNA regulates ribosome structure and function in the mammalian parasite Trypanosoma brucei. Nat Commun, 14, 2023
8FKV	Human nucleolar pre-60S ribosomal subunit (State D1) 分子名称: 28S rRNA, 5.8S rRNA, 60S ribosomal protein L10a, ... 著者 Vanden Broeck, A, Klinge, S. 登録日 2022-12-21 公開日 2023-07-12 最終更新日 2023-07-19 実験手法 ELECTRON MICROSCOPY (2.47 Å) 主引用文献 Principles of human pre-60 S biogenesis. Science, 381, 2023
8CIV	Translocation intermediate 5 (TI-5) of 80S S. cerevisiae ribosome with ligands and eEF2 in the presence of sordarin 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. 登録日 2023-02-10 公開日 2023-09-20 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.47 Å) 主引用文献 mRNA reading frame maintenance during eukaryotic ribosome translocation. Nature, 625, 2024
7S1J	Wild-type Escherichia coli ribosome with antibiotic radezolid 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Young, I.D, Stojkovic, V, Tsai, K, Lee, D.J, Fraser, J.S, Galonic Fujimori, D. 登録日 2021-09-02 公開日 2022-03-02 実験手法 ELECTRON MICROSCOPY (2.47 Å) 主引用文献 Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics. Nat.Struct.Mol.Biol., 29, 2022
3CEM	Human glycogen phosphorylase (tense state) in complex with the allosteric inhibitor AVE9423 分子名称: 1-(2-carboxyphenyl)-7-chloro-6-[(2-chloro-4,6-difluorophenyl)amino]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, Glycogen phosphorylase, liver form, ... 著者 Wendt, K.U, Dreyer, M.K, Anderka, O, Klabunde, T, Loenze, P, Defossa, E, Schmoll, D. 登録日 2008-02-29 公開日 2008-05-27 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.47 Å) 主引用文献 Thermodynamic characterization of allosteric glycogen phosphorylase inhibitors. Biochemistry, 47, 2008
3LDW	Crystal Structure of Plasmodium vivax geranylgeranylpyrophosphate synthase PVX_092040 with zoledronate and IPP bound 分子名称: 1,2-ETHANEDIOL, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Farnesyl pyrophosphate synthase, ... 著者 Wernimont, A.K, Lew, J, Zhao, Y, Kozieradzki, I, Cossar, D, Schapira, M, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Hui, R, Artz, J.D, Structural Genomics Consortium (SGC) 登録日 2010-01-13 公開日 2010-11-17 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.47 Å) 主引用文献 Molecular characterization of a novel geranylgeranyl pyrophosphate synthase from Plasmodium parasites. J.Biol.Chem., 286, 2011
4FPA	Crystal Structure of recombinant human Hexokinase type I mutant D413N Glucose 6-Phosphate 分子名称: 6-O-phosphono-beta-D-glucopyranose, CITRIC ACID, Hexokinase-1, ... 著者 Shen, L, Honzatko, R.B. 登録日 2012-06-21 公開日 2013-07-03 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 DETERMINATION OF SITE AFFINITY CONSTANTS FOR PRODUCT INHIBITION of WILD-TYPE AND MUTANT FORMS OF RECOMBINANT HUMAN HEXOKINASE TYPE I To be Published
7ASM	Staphylococcus aureus 50S after 30 minutes incubation at 37C 分子名称: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... 著者 Cimicata, G, Bashan, A, Yonath, A. 登録日 2020-10-27 公開日 2021-11-17 実験手法 ELECTRON MICROSCOPY (2.48 Å) 主引用文献 Staphylococcus aureus 50S after 30 minutes incubation a 37C To Be Published
8FLE	Human nuclear pre-60S ribosomal subunit (State L2) 分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Vanden Broeck, A, Klinge, S. 登録日 2022-12-21 公開日 2023-07-12 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.48 Å) 主引用文献 Principles of human pre-60 S biogenesis. Science, 381, 2023
7S1I	Wild-type Escherichia coli stalled ribosome with antibiotic radezolid 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Young, I.D, Stojkovic, V, Tsai, K, Lee, D.J, Fraser, J.S, Galonic Fujimori, D. 登録日 2021-09-02 公開日 2022-03-02 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (2.48 Å) 主引用文献 Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics. Nat.Struct.Mol.Biol., 29, 2022
7S1G	wild-type Escherichia coli stalled ribosome with antibiotic linezolid 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Young, I.D, Stojkovic, V, Tsai, K, Lee, D.J, Fraser, J.S, Galonic Fujimori, D. 登録日 2021-09-02 公開日 2021-11-17 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (2.48 Å) 主引用文献 Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics. Nat.Struct.Mol.Biol., 29, 2022
2C7W	Crystal Structure of human vascular endothelial growth factor-B: Identification of amino acids important for angiogeninc activity 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, VASCULAR ENDOTHELIAL GROWTH FACTOR B PRECURSOR 著者 Iyer, S, Scotney, P.D, Nash, A.D, Acharya, K.R. 登録日 2005-11-29 公開日 2007-01-30 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Crystal Structure of Human Vascular Endothelial Growth Factor-B: Identification of Amino Acids Important for Receptor Binding J.Mol.Biol., 359, 2006
2EWG	T. brucei Farnesyl Diphosphate Synthase Complexed with Minodronate 分子名称: (1-HYDROXY-2-IMIDAZO[1,2-A]PYRIDIN-3-YLETHANE-1,1-DIYL)BIS(PHOSPHONIC ACID), MAGNESIUM ION, S-1,2-PROPANEDIOL, ... 著者 Cao, R, Mao, J, Gao, Y, Robinson, H, Odeh, S, Goddard, A, Oldfield, E. 登録日 2005-11-03 公開日 2006-10-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Solid-state NMR, crystallographic, and computational investigation of bisphosphonates and farnesyl diphosphate synthase-bisphosphonate complexes. J.Am.Chem.Soc., 128, 2006
8FRU	60S subunit of the Giardia lamblia 80S ribosome 分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Eiler, D.R, Wimberly, B.T, Bilodeau, D.Y, Rissland, O.S, Kieft, J.S. 登録日 2023-01-08 公開日 2024-01-31 最終更新日 2024-04-17 実験手法 ELECTRON MICROSCOPY (2.49 Å) 主引用文献 The Giardia lamblia ribosome structure reveals divergence in several biological pathways and the mode of emetine function. Structure, 32, 2024
8P2H	Staphylococcus aureus 70S ribosome with elongation factor G locked with fusidic acid with a tRNA in pe/E chimeric state 分子名称: 1,4-DIAMINOBUTANE, 16S ribosomal RNA, 23S ribosomal RNA, ... 著者 Gonzalez-Lopez, A, Selmer, M. 登録日 2023-05-16 公開日 2024-05-01 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (2.49 Å) 主引用文献 Structures of the Staphylococcus aureus ribosome inhibited by fusidic acid and fusidic acid cyclopentane. Sci Rep, 14, 2024
7M4Y	A. baumannii Ribosome-Eravacycline complex: E-site tRNA 70S 分子名称: 16s Ribosomal RNA, 23s ribosomal RNA, 30S ribosomal protein S10, ... 著者 Morgan, C.E, Yu, E.W. 登録日 2021-03-22 公開日 2021-05-19 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 Cryo-EM Determination of Eravacycline-Bound Structures of the Ribosome and the Multidrug Efflux Pump AdeJ of Acinetobacter baumannii. Mbio, 12, 2021
1VQ7	The structure of the transition state analogue "DCA" bound to the large ribosomal subunit of haloarcula marismortui 分子名称: 23S ribosomal rna, 5'-R(*CP*CP*(5AA)P*(2OP)P*(PAE)P*AP*C*C)-3'), 50S RIBOSOMAL PROTEIN L10E, ... 著者 Schmeing, T.M, Steitz, T.A. 登録日 2004-12-16 公開日 2005-11-29 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 An induced-fit mechanism to promote peptide bond formation and exclude hydrolysis of peptidyl-tRNA. Nature, 438, 2005
5ZE6	CRYSTAL STRUCTURE OF OCTAPRENYL PYROPHOSPHATE SYNTHASE FROM ESCHERICHIA COLI WITH BPH-981 分子名称: 2-hydroxy-6-(tetradecyloxy)benzoic acid, MAGNESIUM ION, Octaprenyl diphosphate synthase 著者 Han, X, Liu, W.D, Zheng, Y.Y, Ko, T.P, Chen, C.C, Guo, R.T. 登録日 2018-02-26 公開日 2019-02-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Discovery of Lipophilic Bisphosphonates That Target Bacterial Cell Wall and Quinone Biosynthesis. J.Med.Chem., 62, 2019
6YSI	Acinetobacter baumannii ribosome-tigecycline complex - 50S subunit 分子名称: 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... 著者 Nicholson, D, Edwards, T.A, O'Neill, A.J, Ranson, N.A. 登録日 2020-04-22 公開日 2020-09-16 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 Structure of the 70S Ribosome from the Human Pathogen Acinetobacter baumannii in Complex with Clinically Relevant Antibiotics. Structure, 28, 2020
6R0H	Glycogen Phosphorylase b in complex with 3 分子名称: 3-(4-fluorophenyl)-~{N}-[(2~{R},3~{R},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]benzamide, Glycogen phosphorylase, muscle form, ... 著者 Tsagkarakou, S.A, Koulas, M.S, Kyriakis, E, Stravodimos, G.A, Skamnaki, V.T, Leonidas, D.D. 登録日 2019-03-13 公開日 2019-04-10 最終更新日 2019-04-24 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 High Consistency of Structure-Based Design and X-Ray Crystallography: Design, Synthesis, Kinetic Evaluation and Crystallographic Binding Mode Determination of Biphenyl-N-acyl-beta-d-Glucopyranosylamines as Glycogen Phosphorylase Inhibitors. Molecules, 24, 2019
1N8T	The crystal structure of phosphoglucose isomerase from rabbit muscle 分子名称: Glucose-6-phosphate isomerase 著者 Davies, C, Muirhead, H. 登録日 2002-11-21 公開日 2003-03-04 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of native phosphoglucose isomerase from rabbit: conformational changes associated with catalytic function. Acta Crystallogr.,Sect.D, 59, 2003
1MKG	DISULFIDE DEFICIENT MUTANT OF VASCULAR ENDOTHELIAL GROWTH FACTOR A (C57A and C102A) 分子名称: Vascular Endothelial Growth Factor A 著者 Muller, Y.A, Heiring, C, Misselwitz, R, Welfle, K, Welfle, H. 登録日 2002-08-29 公開日 2002-12-11 最終更新日 2021-10-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The cystine knot promotes folding and not thermodynamic stability in vascular endothelial growth factor J.Biol.Chem., 277, 2002

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