PDB: 10970 件ウェブページステータス検索Chemie searchBIRD

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4KK4	YwlE arginine phosphatase - C7S mutant with phosphorylated active site serine 分子名称: Low molecular weight protein-tyrosine-phosphatase YwlE 著者 Fuhrmann, J, Clausen, T. 登録日 2013-05-05 公開日 2013-07-03 最終更新日 2013-07-17 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural basis for recognizing phosphoarginine and evolving residue-specific protein phosphatases in gram-positive bacteria. Cell Rep, 3, 2013
4H6T	Crystal structure of prethrombin-2 mutant E14eA/D14lA/E18A/S195A 分子名称: PHOSPHATE ION, Prothrombin 著者 Pozzi, N, Chen, Z, Zapata, F, Pelc, L.A, Di Cera, E. 登録日 2012-09-19 公開日 2013-03-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Autoactivation of thrombin precursors. J.Biol.Chem., 288, 2013
4OE6	Crystal Structure of Yeast ALDH4A1 分子名称: Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial 著者 Tanner, J.J. 登録日 2014-01-11 公開日 2014-02-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.951 Å) 主引用文献 Structural Studies of Yeast Delta (1)-Pyrroline-5-carboxylate Dehydrogenase (ALDH4A1): Active Site Flexibility and Oligomeric State. Biochemistry, 53, 2014
6TXZ	FAB PART OF M6903 IN COMPLEX WITH HUMAN TIM3 分子名称: Fab H, Fab L, Hepatitis A virus cellular receptor 2 著者 Musil, D, Sood, V. 登録日 2020-01-15 公開日 2020-04-08 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.06 Å) 主引用文献 Identification and characterization of M6903, an antagonistic anti-TIM-3 monoclonal antibody. Oncoimmunology, 9, 2020
6U9J	Crystal structure of ChuX 分子名称: Heme utilization carrier protein, IMIDAZOLE, PHOSPHATE ION, ... 著者 Mathew, L.G, Lanzilotta, W.N. 登録日 2019-09-09 公開日 2020-09-09 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 New Insight into the Mechanism of Anaerobic Heme Degradation. Biochemistry, 58, 2019
6JUM	MsDpo4-DNA complex 2 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(P*TP*AP*GP*GP*AP*CP*CP*C)-3'), DNA polymerase IV, ... 著者 Nair, D.T, Johnson, M.J. 登録日 2019-04-15 公開日 2020-02-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 A polar filter in DNA polymerases prevents ribonucleotide incorporation. Nucleic Acids Res., 47, 2019
4H6S	Crystal structure of thrombin mutant E14eA/D14lA/E18A/S195A 分子名称: Prothrombin, SODIUM ION 著者 Pozzi, N, Chen, Z, Zapata, F, Pelc, L.A, Di Cera, E. 登録日 2012-09-19 公開日 2013-03-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Autoactivation of thrombin precursors. J.Biol.Chem., 288, 2013
6UE6	PWWP1 domain of NSD2 in complex with MR837 分子名称: 4-cyano-N-cyclopropyl-N-[(thiophen-2-yl)methyl]benzamide, Histone-lysine N-methyltransferase NSD2, UNKNOWN ATOM OR ION 著者 Liu, Y, Tempel, W, De Freitas, R.F, Schapira, M, Brown, P.J, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Min, J, Structural Genomics Consortium (SGC) 登録日 2019-09-20 公開日 2019-11-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Discovery of Small-Molecule Antagonists of the PWWP Domain of NSD2. J.Med.Chem., 64, 2021
4HFP	Structure of thrombin mutant S195a bound to the active site inhibitor argatroban 分子名称: (2R,4R)-4-methyl-1-(N~2~-{[(3S)-3-methyl-1,2,3,4-tetrahydroquinolin-8-yl]sulfonyl}-L-arginyl)piperidine-2-carboxylic acid, Prothrombin, SODIUM ION 著者 Pozzi, N, Chen, Z, Zapata, F, Lin, W, Barranco-Medina, S, Pelc, L.A, Di Cera, E. 登録日 2012-10-05 公開日 2013-03-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Autoactivation of thrombin precursors. J.Biol.Chem., 288, 2013
4IJN	Crystal structure of an acetate kinase from Mycobacterium smegmatis bound to AMP and sulfate 分子名称: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, Acetate kinase, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-12-21 公開日 2013-01-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
4IO6	Crystal Structure of the AvGluR1 ligand binding domain complex with methionine at 1.6 Angstrom resolution 分子名称: AvGluR1 ligand binding domain, CHLORIDE ION, METHIONINE 著者 Lomash, S, Chittori, S, Mayer, M.L. 登録日 2013-01-07 公開日 2013-02-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Anions Mediate Ligand Binding in Adineta vaga Glutamate Receptor Ion Channels. Structure, 21, 2013
4IDD	Structure of the Fragaria x ananassa enone oxidoreductase in complex with NADPH and EHMF 分子名称: (2R)-2-ethyl-4-hydroxy-5-methylfuran-3(2H)-one, 1,2-ETHANEDIOL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Schiefner, A, Skerra, A. 登録日 2012-12-12 公開日 2013-04-17 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural basis for the enzymatic formation of the key strawberry flavor compound 4-hydroxy-2,5-dimethyl-3(2H)-furanone J.Biol.Chem., 288, 2013
4O91	Crystal Structure of type II inhibitor NG25 bound to TAK1-TAB1 分子名称: Mitogen-activated protein kinase kinase kinase 7/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 chimera, N-{4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}-4-methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)benzamide 著者 Gurbani, D, Hunter, J.C, Tan, L, Westover, K.D. 登録日 2013-12-31 公開日 2014-07-30 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.393 Å) 主引用文献 Discovery of Type II Inhibitors of TGF beta-Activated Kinase 1 (TAK1) and Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2). J.Med.Chem., 58, 2015
4IDB	Structure of the Fragaria x ananassa enone oxidoreductase in complex with NADP+ 分子名称: 1,2-ETHANEDIOL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Ripening-induced protein, ... 著者 Schiefner, A, Skerra, A. 登録日 2012-12-12 公開日 2013-04-17 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structural basis for the enzymatic formation of the key strawberry flavor compound 4-hydroxy-2,5-dimethyl-3(2H)-furanone J.Biol.Chem., 288, 2013
4RN6	Structure of prethrombin-2 mutant s195a bound to the active site inhibitor argatroban 分子名称: (2R,4R)-4-methyl-1-(N~2~-{[(3S)-3-methyl-1,2,3,4-tetrahydroquinolin-8-yl]sulfonyl}-L-arginyl)piperidine-2-carboxylic acid, Thrombin heavy chain 著者 Pozzi, N, Chen, Z, Zapata, F, Niu, W, Barranco-Medina, S, Pelc, L.A, Di Cera, E. 登録日 2014-10-23 公開日 2014-11-05 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Autoactivation of thrombin precursors. J.Biol.Chem., 288, 2013
4OE4	Crystal Structure of Yeast ALDH4A1 Complexed with NAD+ 分子名称: Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Tanner, J.J. 登録日 2014-01-11 公開日 2014-02-19 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.168 Å) 主引用文献 Structural Studies of Yeast Delta (1)-Pyrroline-5-carboxylate Dehydrogenase (ALDH4A1): Active Site Flexibility and Oligomeric State. Biochemistry, 53, 2014
6RMM	Crystal structure of TOPBP1 BRCT4,5 in complex with a 53BP1 phosphopeptide 分子名称: 53BP1, DNA topoisomerase 2-binding protein 1 著者 Day, M, Oliver, A.W, Pearl, L.H. 登録日 2019-05-07 公開日 2019-06-12 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.53 Å) 主引用文献 Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint. Elife, 8, 2019
4OOR	Ancestral Steroid Receptor 2 DNA binding domain in complex with a steroid response element 分子名称: 5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*GP*AP*GP*TP*GP*TP*TP*CP*TP*G)-3', 5'-D(*TP*CP*AP*GP*AP*AP*CP*AP*CP*TP*CP*TP*GP*TP*TP*CP*TP*G)-3', Ancestral Steroid Receptor 2 DNA binding domain, ... 著者 Ortlund, E.O, Murphy, M.N. 登録日 2014-02-03 公開日 2014-10-29 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.701 Å) 主引用文献 Evolution of DNA specificity in a transcription factor family produced a new gene regulatory module. Cell(Cambridge,Mass.), 159, 2014
3BSE	Crystal structure analysis of a 16-base-pair B-DNA 分子名称: CALCIUM ION, DNA (5'-D(*DA*DCP*DAP*DCP*DTP*DAP*DCP*DAP*DAP*DTP*DGP*DTP*DTP*DGP*DCP*DAP*DAP*DT)-3'), DNA (5'-D(*DG*DTP*DAP*DTP*DTP*DGP*DCP*DAP*DAP*DCP*DAP*DTP*DTP*DGP*DTP*DAP*DGP*DT)-3') 著者 Narayana, N. 登録日 2007-12-23 公開日 2008-12-23 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystallographic Analysis of a Sex-Specific Enhancer Element: Sequence-Dependent DNA Structure, Hydration, and Dynamics J.Mol.Biol., 385, 2009
4JO8	Crystal structure of the activating Ly49H receptor in complex with m157 (G1F strain) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Killer cell lectin-like receptor 8, M157 著者 Berry, R, Ng, N, Saunders, P.M, Vivian, J.P, Lin, J, Deuss, F.A, Corbett, A.J, Forbes, C.A, Widjaja, J.M, Sullivan, L.C, McAlister, A.D, Perugini, M.A, Call, M.J, Scalzo, A.A, Degli-Esposti, M.A, Coudert, J.D, Beddoe, T, Brooks, A.G, Rossjohn, J. 登録日 2013-03-18 公開日 2013-05-22 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Targeting of a natural killer cell receptor family by a viral immunoevasin Nat.Immunol., 14, 2013
4JOL	Complex structure of AML1-ETO NHR2 domain with HEB fragment 分子名称: Protein CBFA2T1, Transcription factor 12 著者 Wang, Z, Patel, D.J. 登録日 2013-03-18 公開日 2013-06-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.906 Å) 主引用文献 A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis. Nature, 500, 2013
6UF3	Crystal structure of B. subtilis TagV 分子名称: Polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagV 著者 Li, F.K.K, Strynadka, N.C.J. 登録日 2019-09-23 公開日 2020-01-29 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystallographic analysis ofStaphylococcus aureusLcpA, the primary wall teichoic acid ligase. J.Biol.Chem., 295, 2020
4JFH	High Affinity alpha24-beta17 T Cell Receptor for A2 HLA-Melanoma peptide complex 分子名称: 1,2-ETHANEDIOL, GLYCEROL, SULFATE ION, ... 著者 Rizkallah, P.J, Cole, D.K, Madura, F, Sewell, A.K. 登録日 2013-02-28 公開日 2013-05-29 最終更新日 2013-07-17 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 T-cell receptor specificity maintained by altered thermodynamics. J.Biol.Chem., 288, 2013
6JUP	Mutant PolIV-DNA incoming nucleotide complex 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(P*CP*TP*GP*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*CP*C)-3'), DNA (5'-D(P*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*C)-3'), ... 著者 Nair, D.T, Johnson, M.K. 登録日 2019-04-15 公開日 2020-02-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.44 Å) 主引用文献 A polar filter in DNA polymerases prevents ribonucleotide incorporation. Nucleic Acids Res., 47, 2019
4U8Z	Crystal structure of MST3 with a pyrrolopyrimidine inhibitor (PF-06447475) 分子名称: 3-[4-(morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile, MANGANESE (II) ION, Serine/threonine-protein kinase 24 著者 Jasti, J, Song, X, Griffor, M, Kurumbail, R.G. 登録日 2014-08-05 公開日 2015-03-18 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Discovery and preclinical profiling of 3-[4-(morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile (PF-06447475), a highly potent, selective, brain penetrant, and in vivo active LRRK2 kinase inhibitor. J.Med.Chem., 58, 2015

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