4OOR

Ancestral Steroid Receptor 2 DNA binding domain in complex with a steroid response element

Summary for 4OOR

• Entry DOI: 10.2210/pdb4oor/pdb
• Related: 4OLN 4OND
• Descriptor: Ancestral Steroid Receptor 2 DNA binding domain, 5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*GP*AP*GP*TP*GP*TP*TP*CP*TP*G)-3', 5'-D(*TP*CP*AP*GP*AP*AP*CP*AP*CP*TP*CP*TP*GP*TP*TP*CP*TP*G)-3', ... (5 entities in total)
• Functional Keywords: nuclear receptor zinc finger, steroid receptor, transcription factor, dna, coregulators, transcription-dna complex, transcription/dna
• Biological source: synthetic construct
• Total number of polymer chains: 8
• Total formula weight: 58684.75

Authors

Ortlund, E.O.,Murphy, M.N. (deposition date: 2014-02-03, release date: 2014-10-29, Last modification date: 2024-02-28)

• Primary citation: McKeown, A.N.,Bridgham, J.T.,Anderson, D.W.,Murphy, M.N.,Ortlund, E.A.,Thornton, J.W.; Evolution of DNA specificity in a transcription factor family produced a new gene regulatory module.; Cell(Cambridge,Mass.), 159:58-68, 2014; PubMed: 25259920; DOI: 10.1016/j.cell.2014.09.003

Experimental method

X-RAY DIFFRACTION (2.701 Å)