4H6T
Crystal structure of prethrombin-2 mutant E14eA/D14lA/E18A/S195A
Summary for 4H6T
| Entry DOI | 10.2210/pdb4h6t/pdb |
| Related | 3SQH 4H6S |
| Descriptor | Prothrombin, PHOSPHATE ION (3 entities in total) |
| Functional Keywords | serine protease, prethrombin-2, autoactivation, hydrolase |
| Biological source | Homo sapiens (human) |
| Cellular location | Secreted, extracellular space: P00734 |
| Total number of polymer chains | 1 |
| Total formula weight | 35719.90 |
| Authors | Pozzi, N.,Chen, Z.,Zapata, F.,Pelc, L.A.,Di Cera, E. (deposition date: 2012-09-19, release date: 2013-03-13, Last modification date: 2023-09-20) |
| Primary citation | Pozzi, N.,Chen, Z.,Zapata, F.,Niu, W.,Barranco-Medina, S.,Pelc, L.A.,Di Cera, E. Autoactivation of thrombin precursors. J.Biol.Chem., 288:11601-11610, 2013 Cited by PubMed: 23467412DOI: 10.1074/jbc.M113.451542 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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