4H6T
Crystal structure of prethrombin-2 mutant E14eA/D14lA/E18A/S195A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Prothrombin | polymer | 306 | 35055.1 | 1 | UniProt (P00734) Pfam (PF09396) Pfam (PF00089) | Homo sapiens (human) | Coagulation factor II, Activation peptide fragment 1, Activation peptide fragment 2, Thrombin light chain, Thrombin heavy chain |
| 2 | B, C, D, E, F... (A) | PHOSPHATE ION | non-polymer | 95.0 | 7 | Chemie (PO4) | |||
| 3 | I (A) | water | water | 18.0 | 63 | Chemie (HOH) |
Sequence modifications
A: 1 - 247 (UniProt: P00734)
| PDB | External Database | Details |
|---|---|---|
| Ala 14 | Glu 354 | engineered mutation |
| Ala 14 | Asp 361 | engineered mutation |
| Ala 18 | Glu 366 | engineered mutation |
| Ala 195 | Ser 568 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35055.1 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 664.8 | |
| All* | Total formula weight | 35719.9 |
