5WSC
 
 | | Crystal of pyruvate kinase (PYK) from Mycobacterium tuberculosis in complex with Oxalate, soaked with allosteric activators AMP and Glucose 6-Phosphate | | 分子名称: | 6-O-phosphono-alpha-D-glucopyranose, ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Zhong, W, Cai, Q, El Sahili, A, Lescar, J, Dedon, P.C. | | 登録日 | 2016-12-06 | | 公開日 | 2017-11-15 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Allosteric pyruvate kinase-based "logic gate" synergistically senses energy and sugar levels in Mycobacterium tuberculosis.
Nat Commun, 8, 2017
|
|
4X5X
 | |
4X4B
 | |
4X5C
 | | Anthranilate phosphoribosyltransferase variant R193L from Mycobacterium tuberculosis with pyrophosphate/PRPP and Mg2+ bound | | 分子名称: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Anthranilate phosphoribosyltransferase, MAGNESIUM ION, ... | | 著者 | Cookson, T.V.M, Parker, E.J, Lott, J.S. | | 登録日 | 2014-12-05 | | 公開日 | 2015-11-25 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | Structures of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Variants Reveal the Conformational Changes That Facilitate Delivery of the Substrate to the Active Site.
Biochemistry, 54, 2015
|
|
5W8S
 | | Lipid A Disaccharide Synthase (LpxB)-7 solubilizing mutations | | 分子名称: | LITHIUM ION, Lipid-A-disaccharide synthase, SODIUM ION | | 著者 | Bohl, T.E, Aihara, H, Shi, K, Lee, J.K. | | 登録日 | 2017-06-22 | | 公開日 | 2018-01-31 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of lipid A disaccharide synthase LpxB from Escherichia coli.
Nat Commun, 9, 2018
|
|
5WB0
 | |
4X6D
 | | CD1a ternary complex with endogenous lipids and BK6 TCR | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, OLEIC ACID, ... | | 著者 | Birkinshaw, R.W, Rossjohn, J. | | 登録日 | 2014-12-08 | | 公開日 | 2015-01-28 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.98 Å) | | 主引用文献 | alpha beta T cell antigen receptor recognition of CD1a presenting self lipid ligands.
Nat.Immunol., 16, 2015
|
|
5WS9
 | | Pyruvate kinase (PYK) from Mycobacterium tuberculosis in complex with Oxalate, ATP and allosteric activator AMP | | 分子名称: | ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Zhong, W, Cai, Q, El Sahili, A, Lescar, J, Dedon, P.C. | | 登録日 | 2016-12-06 | | 公開日 | 2017-11-15 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Allosteric pyruvate kinase-based "logic gate" synergistically senses energy and sugar levels in Mycobacterium tuberculosis.
Nat Commun, 8, 2017
|
|
5WUD
 | | Structural basis for conductance through TRIC cation channels | | 分子名称: | MAGNESIUM ION, Uncharacterized protein | | 著者 | Su, M, Gao, F, Mao, Y, Li, D.L, Guo, Y.Z, Wang, X.H, Bruni, R, Kloss, B, Hendrickson, W.A, Chen, Y.H, New York Consortium on Membrane Protein Structure (NYCOMPS) | | 登録日 | 2016-12-17 | | 公開日 | 2017-06-21 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural basis for conductance through TRIC cation channels.
Nat Commun, 8, 2017
|
|
5WUN
 | |
4WSN
 | | Crystal structure of the COP9 signalosome, a P1 crystal form | | 分子名称: | COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ... | | 著者 | Bunker, R.D, Lingaraju, G.M, Thoma, N.H. | | 登録日 | 2014-10-28 | | 公開日 | 2015-12-23 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (5.5 Å) | | 主引用文献 | Cullin-RING ubiquitin E3 ligase regulation by the COP9 signalosome.
Nature, 531, 2016
|
|
5WMQ
 | |
5WMW
 | | Structural Insights into Substrate and Inhibitor Binding Sites in Human Indoleamine 2,3-Dioxygenase 1 | | 分子名称: | CYANIDE ION, Indoleamine 2,3-dioxygenase 1, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Lewis-Ballester, A, Yeh, S.R, Pham, K.N, Batabyal, D, Karkashon, S, Bonanno, J.B, Poulos, T.L. | | 登録日 | 2017-07-31 | | 公開日 | 2017-12-06 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | | 主引用文献 | Structural insights into substrate and inhibitor binding sites in human indoleamine 2,3-dioxygenase 1.
Nat Commun, 8, 2017
|
|
5X1J
 | | Vanillate/3-O-methylgallate O-demethylase, LigM, vanillate complex form | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-HYDROXY-3-METHOXYBENZOATE, ... | | 著者 | Harada, A, Senda, T. | | 登録日 | 2017-01-26 | | 公開日 | 2017-05-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The crystal structure of a new O-demethylase from Sphingobium sp. strain SYK-6
FEBS J., 284, 2017
|
|
4WYK
 | |
4WZ4
 | | Crystal structure of P. aeruginosa AmpC | | 分子名称: | Beta-lactamase, GLYCEROL, {(3R)-6-[(3-amino-1,2,4-thiadiazol-5-yl)oxy]-1-hydroxy-4,5-dimethyl-1,3-dihydro-2,1-benzoxaborol-3-yl}acetic acid | | 著者 | Ferguson, A.D. | | 登録日 | 2014-11-18 | | 公開日 | 2015-08-05 | | 最終更新日 | 2018-04-25 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | 4,5-Disubstituted 6-Aryloxy-1,3-dihydrobenzo[c][1,2]oxaboroles Are Broad-Spectrum Serine beta-Lactamase Inhibitors.
ACS Infect Dis, 1, 2015
|
|
5WO2
 | | Chaperone Spy bound to Casein Fragment (Casein un-modeled) | | 分子名称: | CHLORIDE ION, IMIDAZOLE, Periplasmic chaperone Spy, ... | | 著者 | Horowitz, S, Koldewey, P, Martin, R, Bardwell, J.C.A. | | 登録日 | 2017-08-01 | | 公開日 | 2017-08-16 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.769 Å) | | 主引用文献 | Visualizing chaperone-assisted protein folding.
Nat. Struct. Mol. Biol., 23, 2016
|
|
4WZZ
 | | CRYSTAL STRUCTURE OF AN ABC TRANSPORTER SOLUTE BINDING PROTEIN (IPR025997) FROM CLOSTRIDIUM PHYTOFERMENTAS (Cphy_0583, TARGET EFI-511148) WITH BOUND L-RHAMNOSE | | 分子名称: | 1,2-ETHANEDIOL, Putative sugar ABC transporter, substrate-binding protein, ... | | 著者 | Vetting, M.W, Al Obaidi, N.F, Toro, R, Morisco, L.L, Benach, J, Wasserman, S.R, Attonito, J.D, Scott Glenn, A, Chamala, S, Chowdhury, S, Lafleur, J, Love, J, Seidel, R.D, Whalen, K.L, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | | 登録日 | 2014-11-20 | | 公開日 | 2014-12-17 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | CRYSTAL STRUCTURE OF AN ABC TRANSPORTER SOLUTE BINDING PROTEIN (IPR025997) FROM CLOSTRIDIUM PHYTOFERMENTAS (Cphy_0583, TARGET EFI-511148) WITH BOUND L-RHAMNOSE
To be published
|
|
4WVZ
 | | Crystal structure of artificial crosslinked thiol dioxygenase G95C variant from Pseudomonas aeruginosa | | 分子名称: | 3-mercaptopropionate dioxygenase, FE (II) ION | | 著者 | Fellner, M, Tchesnokov, E.P, Jameson, G.N.L, Wilbanks, S.M. | | 登録日 | 2014-11-09 | | 公開日 | 2016-02-24 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Substrate and pH-Dependent Kinetic Profile of 3-Mercaptopropionate Dioxygenase from Pseudomonas aeruginosa.
Biochemistry, 55, 2016
|
|
5WPN
 | | Zn-bound Structure of Chaetopterus variopedatus Ferritin | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | | 著者 | De Meulenaere, E, Bailey, J.B, Tezcan, F.A, Deheyn, D. | | 登録日 | 2017-08-05 | | 公開日 | 2017-12-06 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | | 主引用文献 | First biochemical and crystallographic characterization of a fast-performing ferritin from a marine invertebrate.
Biochem. J., 474, 2017
|
|
4WWR
 | |
4X2O
 | | Sac3N peptide bound to Mex67:Mtr2 | | 分子名称: | Putative SAC3 family protein, Putative mRNA export protein, Putative uncharacterized protein | | 著者 | Aibara, S, Valkov, E, Stewart, M. | | 登録日 | 2014-11-26 | | 公開日 | 2015-06-17 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural Characterization of the Chaetomium thermophilum TREX-2 Complex and its Interaction with the mRNA Nuclear Export Factor Mex67:Mtr2.
Structure, 23, 2015
|
|
5WUM
 | |
4WY6
 | | Crystal structure of human BACE-1 bound to Compound 36 | | 分子名称: | (4aR,6R,8aS)-8a-(2,4-difluorophenyl)-6-(fluoromethyl)-4,4a,5,6,8,8a-hexahydropyrano[3,4-d][1,3]thiazin-2-amine, Beta-secretase 1, DIMETHYL SULFOXIDE, ... | | 著者 | Vajdos, F.F. | | 登録日 | 2014-11-15 | | 公開日 | 2015-03-04 | | 最終更新日 | 2017-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Discovery of a Series of Efficient, Centrally Efficacious BACE1 Inhibitors through Structure-Based Drug Design.
J.Med.Chem., 58, 2015
|
|
4X4F
 | |
