5WMW
Structural Insights into Substrate and Inhibitor Binding Sites in Human Indoleamine 2,3-Dioxygenase 1
Summary for 5WMW
| Entry DOI | 10.2210/pdb5wmw/pdb |
| Descriptor | Indoleamine 2,3-dioxygenase 1, PROTOPORPHYRIN IX CONTAINING FE, CYANIDE ION, ... (5 entities in total) |
| Functional Keywords | dioxygenase tryptophan heme inhibitor, oxidoreductase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 2 |
| Total formula weight | 97505.50 |
| Authors | Lewis-Ballester, A.,Yeh, S.R.,Pham, K.N.,Batabyal, D.,Karkashon, S.,Bonanno, J.B.,Poulos, T.L. (deposition date: 2017-07-31, release date: 2017-12-06, Last modification date: 2023-10-04) |
| Primary citation | Lewis-Ballester, A.,Pham, K.N.,Batabyal, D.,Karkashon, S.,Bonanno, J.B.,Poulos, T.L.,Yeh, S.R. Structural insights into substrate and inhibitor binding sites in human indoleamine 2,3-dioxygenase 1. Nat Commun, 8:1693-1693, 2017 Cited by PubMed: 29167421DOI: 10.1038/s41467-017-01725-8 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.03 Å) |
Structure validation
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