PDB: 95574 件ウェブページステータス検索Chemie searchBIRD

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8WJ3	Cryo-EM structure of a bacterial protein 分子名称: Helicase HerA central domain-containing protein, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER 著者 Yu, G, Liao, F, Li, X, Li, Z, Zhang, H. 登録日 2023-09-25 公開日 2024-09-11 実験手法 ELECTRON MICROSCOPY (3.36 Å) 主引用文献 Cryo-EM structure of a bacterial protein To Be Published
8WIV	Cryo-EM structure of a bacterial protein 分子名称: Helicase HerA central domain-containing protein, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER 著者 Yu, G, Liao, F, Li, X, Li, Z, Zhang, H. 登録日 2023-09-25 公開日 2024-09-11 実験手法 ELECTRON MICROSCOPY (3.41 Å) 主引用文献 Cryo-EM structure of a bacterial protein To Be Published
7NH4	Co-Crystal Structure of Akt1 in Complex with Covalent-Allosteric Akt Inhibitor 3 分子名称: ACETATE ION, RAC-alpha serine/threonine-protein kinase, ~{N}-[3-[1-[[4-[5-(hydroxymethyl)-3-phenyl-pyridin-2-yl]phenyl]methyl]piperidin-4-yl]-2-oxidanylidene-1~{H}-benzimidazol-5-yl]propanamide 著者 Landel, I, Mueller, M.P, Rauh, D. 登録日 2021-02-10 公開日 2021-09-08 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Cellular model system to dissect the isoform-selectivity of Akt inhibitors. Nat Commun, 12, 2021
7NH5	Co-Crystal Structure of Akt1 in Complex with Covalent-Allosteric Akt Inhibitor 6 分子名称: ACETATE ION, RAC-alpha serine/threonine-protein kinase, ~{N}-methyl-6-[4-[[4-[2-oxidanylidene-6-(propanoylamino)-3~{H}-benzimidazol-1-yl]piperidin-1-yl]methyl]phenyl]-5-phenyl-pyridine-3-carboxamide 著者 Landel, I, Mueller, M.P, Rauh, D. 登録日 2021-02-10 公開日 2021-09-08 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Cellular model system to dissect the isoform-selectivity of Akt inhibitors. Nat Commun, 12, 2021
6BRR	Crystal structure of DNMT3A (R836A)-DNMT3L in complex with DNA containing two CpG sites 分子名称: DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, ... 著者 Zhang, Z.M, Song, J. 登録日 2017-11-30 公開日 2018-01-31 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.97 Å) 主引用文献 Structural basis for DNMT3A-mediated de novo DNA methylation. Nature, 554, 2018
1MAF	The Active Site Structure of Methylamine Dehydrogenase: Hydrazines Identify C6 as the Reactive Site of the Tryptophan Derived Quinone Cofactor 分子名称: METHYLAMINE DEHYDROGENASE (HEAVY SUBUNIT), METHYLAMINE DEHYDROGENASE (LIGHT SUBUNIT), NITROGEN MOLECULE 著者 Huizinga, E.G, Vellieux, F.M.D, Hol, W.G.J. 登録日 1992-05-20 公開日 1994-01-31 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Active site structure of methylamine dehydrogenase: hydrazines identify C6 as the reactive site of the tryptophan-derived quinone cofactor. Biochemistry, 31, 1992
4K2F	Structure of Pseudomonas aeruginosa PvdQ bound to BRD-A08522488 分子名称: (2S)-(4-chlorophenyl)(6-chloropyridin-2-yl)ethanenitrile, 1,2-ETHANEDIOL, Acyl-homoserine lactone acylase PvdQ 著者 Drake, E.J, Wurst, J.M, Theriault, J.R, Munoz, B, Gulick, A.M. 登録日 2013-04-09 公開日 2014-06-18 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Identification of Inhibitors of PvdQ, an Enzyme Involved in the Synthesis of the Siderophore Pyoverdine. Acs Chem.Biol., 9, 2014
1MAE	The Active Site Structure of Methylamine Dehydrogenase: Hydrazines Identify C6 as the Reactive Site of the Tryptophan Derived Quinone Cofactor 分子名称: METHYLAMINE DEHYDROGENASE (HEAVY SUBUNIT), METHYLAMINE DEHYDROGENASE (LIGHT SUBUNIT), NITROGEN MOLECULE 著者 Huizinga, E.G, Vellieux, F.M.D, Hol, W.G.J. 登録日 1992-05-20 公開日 1994-01-31 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Active site structure of methylamine dehydrogenase: hydrazines identify C6 as the reactive site of the tryptophan-derived quinone cofactor. Biochemistry, 31, 1992
4K24	Structure of anti-uPAR Fab ATN-658 in complex with uPAR 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Urokinase plasminogen activator surface receptor, ... 著者 Huang, M.D, Xu, X, Yuan, C. 登録日 2013-04-08 公開日 2014-02-26 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (4.5 Å) 主引用文献 Identification of a New Epitope in uPAR as a Target for the Cancer Therapeutic Monoclonal Antibody ATN-658, a Structural Homolog of the uPAR Binding Integrin CD11b ( alpha M) Plos One, 9, 2014
5Z3I	Crystal Structure of Abrin A chain (Recombinant) in complex with Adenine at 1.65 Angstroms 分子名称: ADENINE, Abrin A-chain 著者 Bansia, H, Karande, A.A, Ramakumar, S. 登録日 2018-01-08 公開日 2019-01-02 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structural basis for neutralization of cytotoxic abrin by monoclonal antibody D6F10. FEBS J., 286, 2019
7MYJ	Structure of full length human AMPK (a2b1g1) in complex with a small molecule activator MSG011 分子名称: (5S,6R,7R,9R,13cR,14R,16aS)-6-methoxy-5-methyl-7-(methylamino)-6,7,8,9,14,15,16,16a-octahydro-5H,13cH-5,9-epoxy-4b,9a,1 5-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-14-ol, 5'-AMP-activated protein kinase catalytic subunit alpha-2, 5'-AMP-activated protein kinase subunit beta-1, ... 著者 Ovens, A.J, Gee, Y.S, Ling, N.X.Y, Waters, N.J, Yu, D, Scott, J.W, Parker, M.W, Hoffman, N.J, Kemp, B.E, Baell, J.B, Oakhill, J.S, Langendorf, C.G. 登録日 2021-05-21 公開日 2022-06-29 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Structure-function analysis of the AMPK activator SC4 and identification of a potent pan AMPK activator. Biochem.J., 479, 2022
7NAC	State E2 nucleolar 60S ribosomal biogenesis intermediate - Composite model 分子名称: 25S rRNA, 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ... 著者 Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P. 登録日 2021-06-21 公開日 2022-11-09 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.04 Å) 主引用文献 Sequence-specific remodeling of a topologically complex RNP substrate by Spb4. Nat.Struct.Mol.Biol., 29, 2022
6C5X	Crystal Structure of SOCS1 in complex with ElonginB and ElonginC 分子名称: Elongin-B, Elongin-C, GP130 peptide fragment, ... 著者 Kershaw, N.J, Laktyushin, A, Babon, J.J. 登録日 2018-01-17 公開日 2018-05-02 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3.105 Å) 主引用文献 The molecular basis of JAK/STAT inhibition by SOCS1. Nat Commun, 9, 2018
6C7Y	Crystal structure of inhibitory protein SOCS1 in complex with JAK1 kinase domain 分子名称: 1,2-ETHANEDIOL, ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Liau, N.P.D, Laktyushin, A, Lucet, I.S, Murphy, J.M, Yao, S, Callaghan, K, Nicola, N.A, Kershaw, N.J, Babon, J.J. 登録日 2018-01-23 公開日 2018-05-02 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.499 Å) 主引用文献 The molecular basis of JAK/STAT inhibition by SOCS1. Nat Commun, 9, 2018
6CIB	The structure of YcaO from Methanopyrus kandleri bound with AMPPCP and Mg2+ 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, OXAMIC ACID, ... 著者 Dong, S.-H, Nair, S.K. 登録日 2018-02-23 公開日 2018-03-21 最終更新日 2018-03-28 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Enzymatic reconstitution of ribosomal peptide backbone thioamidation. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4KRD	Crystal Structure of Pho85-Pcl10 Complex 分子名称: Cyclin-dependent protein kinase PHO85, PHO85 cyclin-10 著者 Quiocho, F.A, Zheng, F. 登録日 2013-05-16 公開日 2013-09-18 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.952 Å) 主引用文献 New Structural Insights into Phosphorylation-free Mechanism for Full Cyclin-dependent Kinase (CDK)-Cyclin Activity and Substrate Recognition. J.Biol.Chem., 288, 2013
6CE2	Crystal structure of Myotoxin I (MjTX-I) from Bothrops moojeni complexed to inhibitor suramin 分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON IC ACID, Basic phospholipase A2 homolog 1 著者 Salvador, G.H.M, Fontes, M.R.M. 登録日 2018-02-10 公開日 2018-07-25 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural and functional characterization of suramin-bound MjTX-I from Bothrops moojeni suggests a particular myotoxic mechanism. Sci Rep, 8, 2018
6CI7	The structure of YcaO from Methanopyrus kandleri bound with AMPPCP and Mg2+ 分子名称: MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, YcaO 著者 Dong, S.-H, Nair, S.K. 登録日 2018-02-23 公開日 2018-03-21 最終更新日 2018-03-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Enzymatic reconstitution of ribosomal peptide backbone thioamidation. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4ITQ	Crystal structure of hypothetical protein SCO1480 bound to DNA 分子名称: 5'-D(P*CP*CP*GP*CP*GP*CP*GP*C)-3', 5'-D(P*GP*CP*GP*CP*GP*CP*GP*G)-3', Putative uncharacterized protein SCO1480 著者 Guarne, A, Nanji, T, Gloyd, M, Swiercz, J.P, Elliot, M.A. 登録日 2013-01-18 公開日 2013-03-27 最終更新日 2013-05-22 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 A novel nucleoid-associated protein specific to the actinobacteria. Nucleic Acids Res., 41, 2013
1FYR	DIMER FORMATION THROUGH DOMAIN SWAPPING IN THE CRYSTAL STRUCTURE OF THE GRB2-SH2 AC-PYVNV COMPLEX 分子名称: GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2, HEPATOCYTE GROWTH FACTOR RECEPTOR PEPTIDE 著者 Schiering, N, Casale, E, Caccia, P, Giordano, P, Battistini, C. 登録日 2000-10-03 公開日 2000-12-06 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Dimer formation through domain swapping in the crystal structure of the Grb2-SH2-Ac-pYVNV complex. Biochemistry, 39, 2000
4K23	Structure of anti-uPAR Fab ATN-658 分子名称: anti-uPAR antibody, heavy chain, light chain 著者 Yuan, C, Huang, M, Chen, L. 登録日 2013-04-08 公開日 2014-02-26 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Identification of a New Epitope in uPAR as a Target for the Cancer Therapeutic Monoclonal Antibody ATN-658, a Structural Homolog of the uPAR Binding Integrin CD11b ( alpha M) Plos One, 9, 2014
1J3H	Crystal structure of apoenzyme cAMP-dependent protein kinase catalytic subunit 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, cAMP-dependent protein kinase, alpha-catalytic subunit 著者 Akamine, P, Madhusudan, Wu, J, Xuong, N.H, Ten Eyck, L.F, Taylor, S.S. 登録日 2003-01-31 公開日 2003-03-04 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Dynamic Features of cAMP-dependent Protein Kinase Revealed by Apoenzyme Crystal Structure J.Mol.Biol., 327, 2003
1RY6	Crystal Structure of Internal Kinesin Motor Domain 分子名称: INTERNAL KINESIN, SULFATE ION 著者 Shipley, K, Hekmat-Nejad, M, Turner, J, Moores, C, Anderson, R, Milligan, R, Sakowicz, R, Fletterick, R. 登録日 2003-12-19 公開日 2004-04-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure of a kinesin microtubule depolymerization machine. Embo J., 23, 2004
8TB1	Solution NMR structure of a RiPP proteusin precursor protein 分子名称: NHLP leader peptide family natural product, tumor homing peptide 1 (TH1) substrate chimera 著者 McShan, A.C, Vinayak, A, Nguyen, N.A. 登録日 2023-06-28 公開日 2024-02-14 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Disordered regions in proteusin peptides guide post-translational modification by a flavin-dependent RiPP brominase. Nat Commun, 15, 2024
4H2W	Crystal structure of engineered Bradyrhizobium japonicum glycine:[carrier protein] ligase complexed with carrier protein from Agrobacterium tumefaciens and AMP 分子名称: 4'-PHOSPHOPANTETHEINE, ADENOSINE MONOPHOSPHATE, Amino acid--[acyl-carrier-protein] ligase 1, ... 著者 Luic, M, Weygand-Durasevic, I, Ivic, N, Mocibob, M. 登録日 2012-09-13 公開日 2013-03-06 最終更新日 2017-08-23 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Adaptation of aminoacyl-tRNA synthetase catalytic core to carrier protein aminoacylation. Structure, 21, 2013

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