PDB: 42250 件ウェブページステータス検索Chemie searchBIRD

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5FBD	S1 nuclease from Aspergillus oryzae in complex with phosphate and 2'-deoxycytidine 分子名称: 2'-DEOXYCYTIDINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Nuclease S1, ... 著者 Koval, T, Oestergaard, L.H, Dohnalek, J. 登録日 2015-12-14 公開日 2016-12-28 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural and Catalytic Properties of S1 Nuclease from Aspergillus oryzae Responsible for Substrate Recognition, Cleavage, Non-Specificity, and Inhibition. PLoS ONE, 11, 2016
5FDW	Structure of HLA-A2:01 with peptide Y10L 分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... 著者 Zajonc, D.M, Remesh, S.G. 登録日 2015-12-16 公開日 2016-12-21 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Unconventional Peptide Presentation by Major Histocompatibility Complex (MHC) Class I Allele HLA-A*02:01: BREAKING CONFINEMENT. J. Biol. Chem., 292, 2017
5FBB	S1 nuclease from Aspergillus oryzae in complex with phosphate and adenosine 5'-monophosphate 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ... 著者 Koval, T, Oestergaard, L.H, Dohnalek, J. 登録日 2015-12-14 公開日 2016-12-28 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural and Catalytic Properties of S1 Nuclease from Aspergillus oryzae Responsible for Substrate Recognition, Cleavage, Non-Specificity, and Inhibition. PLoS ONE, 11, 2016
5FH5	The structure of rat cytosolic PEPCK variant E89Q in complex with phosphoglycolate and GDP 分子名称: 2-PHOSPHOGLYCOLIC ACID, GUANOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... 著者 Johnson, T.A, Holyoak, T. 登録日 2015-12-21 公開日 2016-11-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Utilization of Substrate Intrinsic Binding Energy for Conformational Change and Catalytic Function in Phosphoenolpyruvate Carboxykinase. Biochemistry, 55, 2016
4NXH	2'-Trifluoromethylthiouridine-modified E. coli 23S rRNA Sarcin Ricin Loop 分子名称: 23S ribosomal RNA Sarcin Ricin Loop, GLYCEROL, SULFATE ION 著者 Ennifar, E, Micura, R, Kosutic, M. 登録日 2013-12-09 公開日 2014-12-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.158 Å) 主引用文献 Surprising base pairing and structural properties of 2'-trifluoromethylthio-modified ribonucleic acids. J.Am.Chem.Soc., 136, 2014
5ESC	Crystal structure of Group A Streptococcus HupZ 分子名称: HupZ 著者 Agniswamy, J, Weber, I.T. 登録日 2015-11-16 公開日 2016-05-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 In vitro heme biotransformation by the HupZ enzyme from Group A streptococcus. Biometals, 29, 2016
5ET5	Human muscle fructose-1,6-bisphosphatase in active R-state 分子名称: Fructose-1,6-bisphosphatase isozyme 2 著者 Barciszewski, J, Wisniewski, J, Kolodziejczyk, R, Dzugaj, A, Jaskolski, M, Rakus, D. 登録日 2015-11-17 公開日 2016-04-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 T-to-R switch of muscle fructose-1,6-bisphosphatase involves fundamental changes of secondary and quaternary structure. Acta Crystallogr D Struct Biol, 72, 2016
4KB7	HCV NS5B GT1B N316Y with CMPD 32 分子名称: 5-cyclopropyl-2-(4-fluorophenyl)-6-[{2-[(3R)-1-hydroxy-1,3-dihydro-2,1-benzoxaborol-3-yl]ethyl}(methylsulfonyl)amino]-N-methyl-1-benzofuran-3-carboxamide, HCV Polymerase 著者 Williams, S.P, Kahler, K.M, Shotwell, J.B. 登録日 2013-04-23 公開日 2013-05-08 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Discovery of a Potent Boronic Acid Derived Inhibitor of the HCV RNA-Dependent RNA Polymerase. J.Med.Chem., 57, 2014
5D0A	Crystal structure of epoxyqueuosine reductase with cleaved RNA stem loop 分子名称: COBALAMIN, Epoxyqueuosine reductase, GLYCEROL, ... 著者 Dowling, D.P, Miles, Z.D, Kohrer, C, Bandarian, V, Drennan, C.L. 登録日 2015-08-03 公開日 2016-09-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Molecular basis of cobalamin-dependent RNA modification. Nucleic Acids Res., 44, 2016
5FLX	Mammalian 40S HCV-IRES complex 分子名称: 18S RRNA, 40S RIBOSOMAL PROTEIN S10, 40S RIBOSOMAL PROTEIN S11, ... 著者 Yamamoto, H, Collier, M, Loerke, J, Ismer, J, Schmidt, A, Hilal, T, Sprink, T, Yamamoto, K, Mielke, T, Burger, J, Shaikh, T.R, Dabrowski, M, Hildebrand, P.W, Scheerer, P, Spahn, C.M.T. 登録日 2015-10-28 公開日 2015-12-23 最終更新日 2024-11-13 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Molecular Architecture of the Ribosome-Bound Hepatitis C Virus Internal Ribosomal Entry Site RNA. Embo J., 34, 2015
8D95	Scaffold Hopping via Ring Opening Enables Identification of Acyclic Compounds as New Complement Factor D Inhibitors 分子名称: Complement factor D, N-(6-bromopyridin-2-yl)-1-[(3-cyanophenyl)acetyl]-L-prolinamide 著者 Raman, K, Babu, Y.S. 登録日 2022-06-09 公開日 2022-11-02 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.166 Å) 主引用文献 Scaffold hopping via ring opening enables identification of acyclic compounds as new complement Factor D inhibitors. Bioorg.Med.Chem., 74, 2022
6CYA	Rotavirus SA11 NSP2 S313A mutant 分子名称: CHLORIDE ION, GLYCEROL, Non-structural protein 2 著者 Anish, R, Hu, L, Prasad, B.V.V. 登録日 2018-04-05 公開日 2018-12-05 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Phosphorylation cascade regulates the formation and maturation of rotaviral replication factories. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5EE7	Crystal structure of the human glucagon receptor (GCGR) in complex with the antagonist MK-0893 分子名称: 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, 3-[[4-[(1~{S})-1-[3-[3,5-bis(chloranyl)phenyl]-5-(6-methoxynaphthalen-2-yl)pyrazol-1-yl]ethyl]phenyl]carbonylamino]propanoic acid, Glucagon receptor,Endolysin,Glucagon receptor, ... 著者 Jazayeri, A, Dore, A.S, Lamb, D, Krishnamurthy, H, Southall, S.M, Baig, A.H, Bortolato, A, Koglin, M, Robertson, N.J, Errey, J.C, Andrews, S.P, Brown, A.J.H, Cooke, R.M, Weir, M, Marshall, F.H. 登録日 2015-10-22 公開日 2016-04-20 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Extra-helical binding site of a glucagon receptor antagonist. Nature, 533, 2016
5FH0	The structure of rat cytosolic PEPCK variant E89A complex with GTP 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... 著者 Johnson, T.A, Holyoak, T. 登録日 2015-12-21 公開日 2016-11-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Utilization of Substrate Intrinsic Binding Energy for Conformational Change and Catalytic Function in Phosphoenolpyruvate Carboxykinase. Biochemistry, 55, 2016
5FH4	The structure of rat cytosolic PEPCK variant E89D in complex with beta-sulfopyruvate and GTP 分子名称: 1,2-ETHANEDIOL, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... 著者 Johnson, T.A, Holyoak, T. 登録日 2015-12-21 公開日 2016-11-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Utilization of Substrate Intrinsic Binding Energy for Conformational Change and Catalytic Function in Phosphoenolpyruvate Carboxykinase. Biochemistry, 55, 2016
4KHR	HCV NS5B GT1A C316Y with GSK5852 分子名称: NS5B RNA-dependent RNA polymerase, SULFATE ION, [4-({[5-cyclopropyl-2-(4-fluorophenyl)-3-(methylcarbamoyl)-1-benzofuran-6-yl](methylsulfonyl)amino}methyl)-2-fluorophenyl]boronic acid 著者 Williams, S.P, Kahler, K.M, Shotwell, J.B. 登録日 2013-05-01 公開日 2013-05-29 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Discovery of a Potent Boronic Acid Derived Inhibitor of the HCV RNA-Dependent RNA Polymerase. J.Med.Chem., 57, 2014
5FB9	S1 nuclease from Aspergillus oryzae with unoccupied active site 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Nuclease S1, ... 著者 Koval, T, Oestergaard, L.H, Dohnalek, J. 登録日 2015-12-14 公開日 2016-12-28 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural and Catalytic Properties of S1 Nuclease from Aspergillus oryzae Responsible for Substrate Recognition, Cleavage, Non-Specificity, and Inhibition. PLoS ONE, 11, 2016
5EBE	Structure of human sphingomyelinase phosphodiesterase like 3A (SMPDL3A) with 5' CMP 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-O-phosphono-beta-D-ribofuranose, ... 著者 Lim, S.M, Yeung, K, Tresaugues, L, Teo, H.L, Nordlund, P. 登録日 2015-10-19 公開日 2016-01-20 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The structure and catalytic mechanism of human sphingomyelin phosphodiesterase like 3a - an acid sphingomyelinase homologue with a novel nucleotide hydrolase activity. Febs J., 283, 2016
4NUT	Crystal structure of the complex between Snu13p and the PEP domain of Rsa1 分子名称: 13 kDa ribonucleoprotein-associated protein, Ribosome assembly 1 protein, SULFATE ION 著者 Charron, C, Chagot, M.E, Manival, X, Branlant, C, Charpentier, B. 登録日 2013-12-04 公開日 2014-12-10 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Proteomic and 3D structure analyses highlight the C/D box snoRNP assembly mechanism and its control J.Cell Biol., 207, 2014
5EOT	Structure of HLA-A2:01 with peptide G13E 分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... 著者 Zajonc, D.M, Remesh, S.G. 登録日 2015-11-10 公開日 2016-12-07 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Unconventional Peptide Presentation by Major Histocompatibility Complex (MHC) Class I Allele HLA-A*02:01: BREAKING CONFINEMENT. J. Biol. Chem., 292, 2017
4OGL	X-ray structure uridine phosphorylase from Vibrio cholerae in complex with thymine at 1.25 A resolution 分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, ... 著者 Prokofev, I.I, Lashkov, A.A, Gabdoulkhakov, A.G, Betzel, C, Mikhailov, A.M. 登録日 2014-01-16 公開日 2015-03-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.249 Å) 主引用文献 X-ray structure uridine phosphorylase from Vibrio cholerae in complex with thymine at 1.25 A resolution Crystallogr. Rep., 2016
5DMB	Crystal structure of a translational regulator bound to a flagellar assembly factor 分子名称: Carbon storage regulator homolog, Flagellar assembly factor FliW 著者 Altegoer, F, Bange, G. 登録日 2015-09-08 公開日 2016-08-24 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.301 Å) 主引用文献 Structural basis for the CsrA-dependent modulation of translation initiation by an ancient regulatory protein. Proc.Natl.Acad.Sci.USA, 113, 2016
6DZD	Crystal structure of Bacillus licheniformis hypothetical protein YfiH 分子名称: CHLORIDE ION, POTASSIUM ION, SODIUM ION, ... 著者 Almeida, L.R, Grejo, M.P, Mulinari, E.J, Santos, J.C, Camargo, S, Bernardes, A, Muniz, J.R.C. 登録日 2018-07-03 公開日 2019-09-11 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.66 Å) 主引用文献 Crystal structure of Bacillus licheniformis hypothetical protein YfiH To Be Published
5E01	Crystal structure of HiNmlR, a MerR family regulator lacking the sensor domain, bound to palyndromic promoter DNA 分子名称: 5'-D(*CP*TP*TP*AP*GP*AP*GP*TP*GP*CP*AP*CP*TP*CP*TP*AP*AP*G)-3', Uncharacterized HTH-type transcriptional regulator HI_0186 著者 Counago, R.M, Chang, C.W, Chen, N.H, Djoko, K.Y, McEwan, A.G, Kobe, B. 登録日 2015-09-26 公開日 2016-06-29 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis of thiol-based regulation of formaldehyde detoxification in H. influenzae by a MerR regulator with no sensor region. Nucleic Acids Res., 44, 2016
5FBC	S1 nuclease from Aspergillus oryzae in complex with 2'-deoxyadenosine-5'-thio-monophosphate (5'dAMP(S)). 分子名称: 2-DEOXY-ADENOSINE -5'-THIO-MONOPHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... 著者 Koval, T, Oestergaard, L.H, Dohnalek, J. 登録日 2015-12-14 公開日 2016-12-28 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural and Catalytic Properties of S1 Nuclease from Aspergillus oryzae Responsible for Substrate Recognition, Cleavage, Non-Specificity, and Inhibition. PLoS ONE, 11, 2016

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