1DF7
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![BU of 1df7 by Molmil](/molmil-images/mine/1df7) | DIHYDROFOLATE REDUCTASE OF MYCOBACTERIUM TUBERCULOSIS COMPLEXED WITH NADPH AND METHOTREXATE | 分子名称: | DIHYDROFOLATE REDUCTASE, GLYCEROL, METHOTREXATE, ... | 著者 | Li, R, Sirawaraporn, R, Chitnumsub, P, Sirawaraporn, W, Wooden, J, Athappilly, F, Turley, S, Hol, W.G. | 登録日 | 1999-11-17 | 公開日 | 2000-03-09 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Three-dimensional structure of M. tuberculosis dihydrofolate reductase reveals opportunities for the design of novel tuberculosis drugs. J.Mol.Biol., 295, 2000
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1DG7
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![BU of 1dg7 by Molmil](/molmil-images/mine/1dg7) | DIHYDROFOLATE REDUCTASE OF MYCOBACTERIUM TUBERCULOSIS COMPLEXED WITH NADPH AND 4-BROMO WR99210 | 分子名称: | 1-[3-(4-BROMO-PHENOXY)-PROPOXY]-6,6-DIMETHYL-1.6-DIHYDRO-[1,3,5]TRIAZINE-2,4-DIAMINE, DIHYDROFOLATE REDUCTASE, GLYCEROL, ... | 著者 | Li, R, Sirawaraporn, R, Chitnumsub, P, Sirawaraporn, W, Wooden, J, Athappilly, F, Turley, S, Hol, W.G. | 登録日 | 1999-11-23 | 公開日 | 2000-03-09 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Three-dimensional structure of M. tuberculosis dihydrofolate reductase reveals opportunities for the design of novel tuberculosis drugs. J.Mol.Biol., 295, 2000
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5C24
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![BU of 5c24 by Molmil](/molmil-images/mine/5c24) | Crystal Structure of HIV-1 Reverse Transcriptase in Complex with 7-((4-((4-cyanophenyl)amino)-1,3,5-triazin-2-yl)amino)-6,8-dimethylindolizine-2-carbonitrile (JLJ605), a non-nucleoside inhibitor | 分子名称: | 6-({4-[(4-cyanophenyl)amino]-1,3,5-triazin-2-yl}amino)-5,7-dimethylindolizine-2-carbonitrile, HIV-1 REVERSE TRANSCRIPTASE, P51 SUBUNIT, ... | 著者 | Frey, K.M, Anderson, K.S. | 登録日 | 2015-06-15 | 公開日 | 2015-07-29 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Discovery and crystallography of bicyclic arylaminoazines as potent inhibitors of HIV-1 reverse transcriptase. Bioorg.Med.Chem.Lett., 25, 2015
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2FDE
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![BU of 2fde by Molmil](/molmil-images/mine/2fde) | Wild type HIV protease bound with GW0385 | 分子名称: | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL [(1S,2R)-3-[(1,3-BENZODIOXOL-5-YLSULFONYL)(ISOBUTYL)AMINO]-2-HYDROXY-1-{4-[(2-METHYL-1,3-THIAZOL-4-YL)METHOXY]BENZYL}PROPYL]CARBAMATE, Gag-Pol polyprotein, POTASSIUM ION | 著者 | Xu, R.X. | 登録日 | 2005-12-13 | 公開日 | 2006-02-21 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Ultra-potent P1 modified arylsulfonamide HIV protease inhibitors: The discovery of GW0385. Bioorg.Med.Chem.Lett., 16, 2006
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5N0H
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![BU of 5n0h by Molmil](/molmil-images/mine/5n0h) | Crystal structure of NDM-1 in complex with hydrolyzed meropenem - new refinement | 分子名称: | (2S,3R)-2-[(2S,3R)-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfan yl-3-methyl-2,3-dihydro-1H-pyrrole-5-carboxylic acid, GLYCEROL, Metallo-beta-lactamase type 2, ... | 著者 | Raczynska, J.E, Shabalin, I.G, Jaskolski, M, Minor, W, Wlodawer, A, King, D.T, Strynadka, N.C.J. | 登録日 | 2017-02-03 | 公開日 | 2017-04-05 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | A close look onto structural models and primary ligands of metallo-beta-lactamases. Drug Resist. Updat., 40, 2018
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7L2G
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![BU of 7l2g by Molmil](/molmil-images/mine/7l2g) | |
1WZI
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![BU of 1wzi by Molmil](/molmil-images/mine/1wzi) | |
7LMM
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![BU of 7lmm by Molmil](/molmil-images/mine/7lmm) | |
7LMK
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![BU of 7lmk by Molmil](/molmil-images/mine/7lmk) | |
7ZLW
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![BU of 7zlw by Molmil](/molmil-images/mine/7zlw) | NME1 in complex with ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Nucleoside diphosphate kinase A | 著者 | Garcia-Saez, I, Iuso, D, Khochbin, S, Petosa, C. | 登録日 | 2022-04-15 | 公開日 | 2023-08-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Nucleoside diphosphate kinases 1 and 2 regulate a protective liver response to a high-fat diet. Sci Adv, 9, 2023
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7ZL8
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![BU of 7zl8 by Molmil](/molmil-images/mine/7zl8) | NME1 in complex with succinyl-CoA | 分子名称: | Nucleoside diphosphate kinase A, SUCCINYL-COENZYME A | 著者 | Garcia-Saez, I, Iuso, D, Khochbin, S, Petosa, C. | 登録日 | 2022-04-14 | 公開日 | 2023-08-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Nucleoside diphosphate kinases 1 and 2 regulate a protective liver response to a high-fat diet. Sci Adv, 9, 2023
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7ZTK
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![BU of 7ztk by Molmil](/molmil-images/mine/7ztk) | NME1 in complex with CoA | 分子名称: | COENZYME A, Nucleoside diphosphate kinase A | 著者 | Garcia-Saez, I, Iuso, D, Khochbin, S, Petosa, C. | 登録日 | 2022-05-10 | 公開日 | 2023-08-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Nucleoside diphosphate kinases 1 and 2 regulate a protective liver response to a high-fat diet. Sci Adv, 9, 2023
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8A98
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![BU of 8a98 by Molmil](/molmil-images/mine/8a98) | CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : snoRNA MUTANT | 分子名称: | 40S ribosomal protein S12, 40S ribosomal protein S14, 40S ribosomal protein S19-like protein, ... | 著者 | Rajan, K.S, Yonath, A, Bashan, A. | 登録日 | 2022-06-28 | 公開日 | 2023-10-11 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.46 Å) | 主引用文献 | Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification. Cell Rep, 43, 2024
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5NRE
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![BU of 5nre by Molmil](/molmil-images/mine/5nre) | A Native Ternary Complex of Alpha-1,3-Galactosyltransferase (a3GalT) Supports a Conserved Reaction Mechanism for Retaining Glycosyltransferases - a3GalT in complex with lactose - a3GalT-LAT | 分子名称: | N-acetyllactosaminide alpha-1,3-galactosyltransferase, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | 著者 | Albesa-Jove, D, Marina, A, Sainz-Polo, M.A, Guerin, M.E. | 登録日 | 2017-04-22 | 公開日 | 2017-10-11 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Structural Snapshots of alpha-1,3-Galactosyltransferase with Native Substrates: Insight into the Catalytic Mechanism of Retaining Glycosyltransferases. Angew. Chem. Int. Ed. Engl., 56, 2017
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7LNK
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5Z20
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![BU of 5z20 by Molmil](/molmil-images/mine/5z20) | The ternary structure of D-lactate dehydrogenase from Pseudomonas aeruginosa with NADH and oxamate | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, D-lactate dehydrogenase (Fermentative), DI(HYDROXYETHYL)ETHER, ... | 著者 | Furukawa, N, Miyanaga, A, Nakajima, M, Taguchi, H. | 登録日 | 2017-12-28 | 公開日 | 2018-09-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural Basis of Sequential Allosteric Transitions in Tetrameric d-Lactate Dehydrogenases from Three Gram-Negative Bacteria. Biochemistry, 57, 2018
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5NRD
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![BU of 5nrd by Molmil](/molmil-images/mine/5nrd) | A Native Ternary Complex of Alpha-1,3-Galactosyltransferase (a-3GalT) Supports a Conserved Reaction Mechanism for Retaining Glycosyltransferases - alpha-3GalT in complex with Co2+, UDP-Gal and lactose - a3GalT-Co2+-UDP-Gal-LAT-2 | 分子名称: | COBALT (II) ION, GALACTOSE-URIDINE-5'-DIPHOSPHATE, GLYCEROL, ... | 著者 | Albesa-Jove, D, Marina, A, Sainz-Polo, M.A, Guerin, M.E. | 登録日 | 2017-04-22 | 公開日 | 2017-10-11 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Structural Snapshots of alpha-1,3-Galactosyltransferase with Native Substrates: Insight into the Catalytic Mechanism of Retaining Glycosyltransferases. Angew. Chem. Int. Ed. Engl., 56, 2017
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6Z82
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![BU of 6z82 by Molmil](/molmil-images/mine/6z82) | |
4YIL
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![BU of 4yil by Molmil](/molmil-images/mine/4yil) | OYE1 W116A COMPLEXED WITH (Z)-METHYL 3-CYANO-3-(4-FLUOROPHENYL)ACRYLATE IN A NON PRODUCTIVE BINDING MODE | 分子名称: | FLAVIN MONONUCLEOTIDE, MAGNESIUM ION, NADPH dehydrogenase 1, ... | 著者 | Santangelo, S, Brenna, E, Stewart, J.D, Powell III, R.W. | 登録日 | 2015-03-02 | 公開日 | 2016-01-20 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.461 Å) | 主引用文献 | Opposite Enantioselectivity in the Bioreduction of (Z)-beta-Aryl-beta-cyanoacrylates Mediated by the Tryptophan 116 Mutants of Old Yellow Enzyme 1: Synthetic Approach to (R)- and (S)-beta-Aryl-gamma-lactams Adv.Synth.Catal., 357, 2015
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5NR9
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![BU of 5nr9 by Molmil](/molmil-images/mine/5nr9) | A Native Ternary Complex of Alpha-1,3-Galactosyltransferase (alpha-3GalT) Supports a Conserved Reaction Mechanism for Retaining Glycosyltransferases - Unliganded alpha-3GalT | 分子名称: | GLYCEROL, N-acetyllactosaminide alpha-1,3-galactosyltransferase | 著者 | Albesa-Jove, D, Marina, A, Sainz-Polo, M.A, Guerin, M.E. | 登録日 | 2017-04-22 | 公開日 | 2017-10-11 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural Snapshots of alpha-1,3-Galactosyltransferase with Native Substrates: Insight into the Catalytic Mechanism of Retaining Glycosyltransferases. Angew. Chem. Int. Ed. Engl., 56, 2017
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5O40
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![BU of 5o40 by Molmil](/molmil-images/mine/5o40) | SOD1 bound to Ebselen | 分子名称: | N-phenyl-2-selanylbenzamide, SULFATE ION, Superoxide dismutase [Cu-Zn], ... | 著者 | Capper, M.J, Wright, G.S.A, Antonyuk, S.V, Hasnain, S.S. | 登録日 | 2017-05-25 | 公開日 | 2018-06-13 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | The cysteine-reactive small molecule ebselen facilitates effective SOD1 maturation. Nat Commun, 9, 2018
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8WCS
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7LG6
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![BU of 7lg6 by Molmil](/molmil-images/mine/7lg6) | BG505 SOSIP.v5.2 in complex with VRC40.01 and RM19R Fabs | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | 著者 | Cottrell, C.A, Torres, J.L, Wu, N.R, Ward, A.B. | 登録日 | 2021-01-19 | 公開日 | 2021-09-15 | 最終更新日 | 2021-11-17 | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | 主引用文献 | Structural basis of glycan276-dependent recognition by HIV-1 broadly neutralizing antibodies. Cell Rep, 37, 2021
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2X0I
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![BU of 2x0i by Molmil](/molmil-images/mine/2x0i) | 2.9 A RESOLUTION STRUCTURE OF MALATE DEHYDROGENASE FROM ARCHAEOGLOBUS FULGIDUS IN COMPLEX WITH NADH | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, MALATE DEHYDROGENASE, SODIUM ION, ... | 著者 | Irimia, A, Madern, D, Zaccai, G, Vellieux, F.M.D, Karshikoff, A, Tibbelin, G, Ladenstein, R, Lien, T, Birkeland, N.-K. | 登録日 | 2009-12-14 | 公開日 | 2009-12-22 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | 主引用文献 | The 2.9A Resolution Crystal Structure of Malate Dehydrogenase from Archaeoglobus Fulgidus: Mechanisms of Oligomerisation and Thermal Stabilisation. J.Mol.Biol., 335, 2004
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7LAT
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![BU of 7lat by Molmil](/molmil-images/mine/7lat) | |