4YIL
OYE1 W116A COMPLEXED WITH (Z)-METHYL 3-CYANO-3-(4-FLUOROPHENYL)ACRYLATE IN A NON PRODUCTIVE BINDING MODE
Summary for 4YIL
Entry DOI | 10.2210/pdb4yil/pdb |
Related | 4GBU |
Descriptor | NADPH dehydrogenase 1, FLAVIN MONONUCLEOTIDE, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | oxidoreductase, catalytic activity, fmn binding |
Biological source | Saccharomyces pastorianus (Lager yeast) |
Total number of polymer chains | 1 |
Total formula weight | 45275.78 |
Authors | Santangelo, S.,Brenna, E.,Stewart, J.D.,Powell III, R.W. (deposition date: 2015-03-02, release date: 2016-01-20, Last modification date: 2024-01-10) |
Primary citation | Brenna, E.,Crotti, M.,Gatti, F.G.,Monti, D.,Parmeggiani, F.,Powell III, R.W.,Santangelo, S.,Stewart, J.D. Opposite Enantioselectivity in the Bioreduction of (Z)-beta-Aryl-beta-cyanoacrylates Mediated by the Tryptophan 116 Mutants of Old Yellow Enzyme 1: Synthetic Approach to (R)- and (S)-beta-Aryl-gamma-lactams Adv.Synth.Catal., 357:1849-1860., 2015 Cited by DOI: 10.1002/adsc.201500206PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.461 Å) |
Structure validation
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