5N0H

Crystal structure of NDM-1 in complex with hydrolyzed meropenem - new refinement

Summary for 5N0H

Entry DOI	10.2210/pdb5n0h/pdb
Descriptor	Metallo-beta-lactamase type 2, (2S,3R)-2-[(2S,3R)-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl-3-methyl-2,3-dihydro-1H-pyrrole-5-carboxylic acid, ZINC ION, ... (6 entities in total)
Functional Keywords	hydrolase-antibiotic complex, metallo-beta-lactamase, ndm-1, hydrolase/antibiotic
Biological source	Klebsiella pneumoniae
Total number of polymer chains	2
Total formula weight	53138.18
Authors	Raczynska, J.E.,Shabalin, I.G.,Jaskolski, M.,Minor, W.,Wlodawer, A.,King, D.T.,Strynadka, N.C.J. (deposition date: 2017-02-03, release date: 2017-04-05, Last modification date: 2019-10-16)
Primary citation	Raczynska, J.E.,Shabalin, I.G.,Minor, W.,Wlodawer, A.,Jaskolski, M. A close look onto structural models and primary ligands of metallo-beta-lactamases. Drug Resist. Updat., 40:1-12, 2018 Cited by PubMed: 30466711 DOI: 10.1016/j.drup.2018.08.001 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation