5N0H
Crystal structure of NDM-1 in complex with hydrolyzed meropenem - new refinement
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Metallo-beta-lactamase type 2 | polymer | 245 | 25959.3 | 2 | UniProt (C7C422) Pfam (PF00753) | Klebsiella pneumoniae | B2 metallo-beta-lactamase,Beta-lactamase type II,Metallo-beta-lactamase NDM-1,Metallo-beta-lactamase type II,New Delhi metallo-beta-lactamase-1,NDM-1 |
| 2 | C (A) | (2S,3R)-2-[(2S,3R)-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfan yl-3-methyl-2,3-dihydro-1H-pyrrole-5-carboxylic acid | non-polymer | 401.5 | 1 | Chemie (8YL) | |||
| 3 | D, E, I, J (A, B) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 4 | F, G, K, L, M (A, B) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 5 | H (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 6 | N, O (A, B) | water | water | 18.0 | 398 | Chemie (HOH) |
Sequence modifications
A, B: 29 - 270 (UniProt: C7C422)
| PDB | External Database | Details |
|---|---|---|
| Lys 271 | - | expression tag |
| Leu 272 | - | expression tag |
| Unk 273 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 51918.5 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1219.6 | |
| All* | Total formula weight | 53138.2 |
