6Z82

Thalictrum flavumn Norcoclaurine synthase point mutant in complex with a transition state analoge

Summary for 6Z82

• Entry DOI: 10.2210/pdb6z82/pdb
• Descriptor: S-norcoclaurine synthase, 4-[2-[(phenylmethyl)amino]ethyl]benzene-1,2-diol (3 entities in total)
• Functional Keywords: pictet spengler condensation, dopamine, lyase
• Biological source: Thalictrum flavum subsp. glaucum (Yellow meadow rue)
• Total number of polymer chains: 1
• Total formula weight: 18449.30

Authors

Roddan, R.,Sula, A.,Keep, N.H. (deposition date: 2020-06-02, release date: 2020-12-02, Last modification date: 2024-01-24)

• Primary citation: Roddan, R.,Sula, A.,Mendez-Sanchez, D.,Subrizi, F.,Lichman, B.R.,Broomfield, J.,Richter, M.,Andexer, J.N.,Ward, J.M.,Keep, N.H.,Hailes, H.C.; Single step syntheses of (1S)-aryl-tetrahydroisoquinolines by norcoclaurine synthases; Commun Chem, 2020; DOI: 10.1038/s42004-020-00416-8

Experimental method

X-RAY DIFFRACTION (2.3 Å)