PDB: 9786 件ウェブページステータス検索Chemie searchBIRD

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6Y6Q	Structure of Andes virus envelope glycoprotein Gc in postfusion conformation 分子名称: Envelope polyprotein, SULFATE ION, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Serris, A, Rey, F.A, Guardado-Calvo, P. 登録日 2020-02-27 公開日 2020-10-14 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The Hantavirus Surface Glycoprotein Lattice and Its Fusion Control Mechanism. Cell, 183, 2020
5D46	Structural Basis for a New Templated Activity by Terminal Deoxynucleotidyl Transferase: Implications for V(D)J Recombination 分子名称: ACETATE ION, DNA (5'-D(*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*TP*TP*GP*C)-3'), ... 著者 Loc'h, J, Rosario, S, Delarue, M. 登録日 2015-08-07 公開日 2016-07-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural Basis for a New Templated Activity by Terminal Deoxynucleotidyl Transferase: Implications for V(D)J Recombination. Structure, 24, 2016
6YRQ	Crystal structure of the tetramerization domain of the glycoprotein Gn (Andes virus) at pH 4.6 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Serris, A, Rey, F.A, Guardado-Calvo, P. 登録日 2020-04-20 公開日 2020-10-14 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.902 Å) 主引用文献 The Hantavirus Surface Glycoprotein Lattice and Its Fusion Control Mechanism. Cell, 183, 2020
4QYK	Crystal structure of a canine parvovirus variant 分子名称: Capsid protein VP1, MAGNESIUM ION 著者 Lukk, T, Organtini, L.J, Hafenstein, S.U. 登録日 2014-07-24 公開日 2014-12-10 最終更新日 2015-01-28 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Global Displacement of Canine Parvovirus by a Host-Adapted Variant: Structural Comparison between Pandemic Viruses with Distinct Host Ranges. J.Virol., 89, 2015
5APJ	Ligand complex of RORg LBD 分子名称: 2-CHLORO-6-FLUORO-N-[4-[3-(TRIFLUOROMETHYL)PHENYL]SULFONYL-3,5-DIHYDRO-2H-1,4-BENZOXAZEPIN-7-YL]BENZAMIDE, NUCLEAR RECEPTOR COACTIVATOR 2, NUCLEAR RECEPTOR ROR-GAMMA, ... 著者 Xue, Y, Aagaard, A, Narjes, F. 登録日 2015-09-16 公開日 2015-11-25 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Benzoxazepines Achieve Potent Suppression of IL-17 Release in Human T-Helper 17 (TH 17) Cells through an Induced-Fit Binding Mode to the Nuclear Receptor ROR gamma. ChemMedChem, 11, 2016
4MMS	Crystal Structure of Prefusion-stabilized RSV F Variant Cav1 at pH 5.5 分子名称: Fusion glycoprotein F1 fused with Fibritin trimerization domain, Fusion glycoprotein F2, SULFATE ION 著者 Mclellan, J.S, Joyce, M.G, Stewart-Jones, G.B.E, Sastry, M, Yang, Y, Graham, B.S, Kwong, P.D. 登録日 2013-09-09 公開日 2013-11-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.397 Å) 主引用文献 Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus. Science, 342, 2013
5BJT	Crystal structure of human FcRn with a peptide inhibitor at multiple sites 分子名称: Beta-2-microglobulin, IgG receptor FcRn large subunit p51, peptide inhibitor 著者 Nienaber, V, Badger, J. 登録日 2016-10-23 公開日 2017-03-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Hepatic FcRn regulates albumin homeostasis and susceptibility to liver injury. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4MMR	Crystal Structure of Prefusion-stabilized RSV F Variant Cav1 at pH 9.5 分子名称: Fusion glycoprotein F1 fused with Fibritin trimerization domain, Fusion glycoprotein F2 著者 Stewart-Jones, G.B.E, McLellan, J.S, Joyce, M.G, Sastry, M, Yang, Y, Graham, B.S, Kwong, P.D. 登録日 2013-09-09 公開日 2013-11-20 最終更新日 2021-06-02 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus. Science, 342, 2013
4PF5	Crystal structure of Concanavalin A complexed with a synthetic derivative of high-mannose chain 分子名称: 1,2-ETHANEDIOL, 4-(hydroxymethyl)-1-(alpha-D-mannopyranosyl)-1H-1,2,3-triazole, Concanavalin-A, ... 著者 Lafite, P, Daniellou, R. 登録日 2014-04-28 公開日 2014-12-17 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Synthesis of High-Mannose Oligosaccharide Analogues through Click Chemistry: True Functional Mimics of Their Natural Counterparts Against Lectins? Chemistry, 21, 2015
4KPQ	Structure and receptor binding specificity of the hemagglutinin H13 from avian influenza A virus H13N6 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin 著者 Lu, X, Qi, J, Shi, Y, Gao, G. 登録日 2013-05-14 公開日 2013-07-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.502 Å) 主引用文献 Structure and Receptor Binding Specificity of Hemagglutinin H13 from Avian Influenza A Virus H13N6 J.Virol., 87, 2013
5B2C	Crystal structure of Mumps virus hemagglutinin-neuraminidase 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HN protein, SULFATE ION 著者 Kubota, M, Takeuchi, K, Watanabe, S, Ohno, S, Matsuoka, R, Kohda, D, Hiramatsu, H, Suzuki, Y, Nakayama, T, Terada, T, Shimizu, K, Shimizu, N, Yanagi, Y, Hashiguchi, T. 登録日 2016-01-14 公開日 2016-09-28 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.238 Å) 主引用文献 Trisaccharide containing alpha 2,3-linked sialic acid is a receptor for mumps virus Proc.Natl.Acad.Sci.USA, 113, 2016
4MMV	Crystal Structure of Prefusion-stabilized RSV F Variant DS-Cav1-TriC at pH 9.5 分子名称: Fusion glycoprotein F1 fused with Fibritin trimerization domain, Fusion glycoprotein F2 著者 Stewart-Jones, G.B.E, McLellan, J.S, Joyce, M.G, Sastry, M, Yang, Y, Graham, B.S, Kwong, P.D. 登録日 2013-09-09 公開日 2013-11-20 最終更新日 2021-06-02 実験手法 X-RAY DIFFRACTION (2.81 Å) 主引用文献 Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus. Science, 342, 2013
5DO4	Thrombin-RNA aptamer complex 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Pallan, P.S, Egli, M. 登録日 2015-09-10 公開日 2016-09-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.859 Å) 主引用文献 Evoking picomolar binding in RNA by a single phosphorodithioate linkage. Nucleic Acids Res., 44, 2016
4MVL	Crystal structure of an engineered lipocalin (Anticalin H1GA) in complex with the Alzheimer amyloid peptide Abeta1-40 分子名称: Beta-amyloid protein 40, Neutrophil gelatinase-associated lipocalin 著者 Eichinger, A, Skerra, A. 登録日 2013-09-24 公開日 2015-08-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 High-affinity Anticalins with aggregation-blocking activity directed against the Alzheimer beta-amyloid peptide. Biochem.J., 473, 2016
4MMU	Crystal Structure of Prefusion-stabilized RSV F Variant DS-Cav1 at pH 5.5 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F1 fused with Fibritin trimerization domain, Fusion glycoprotein F2, ... 著者 Joyce, M.G, Mclellan, J.S, Stewart-Jones, G.B.E, Sastry, M, Yang, Y, Graham, B.S, Kwong, P.D. 登録日 2013-09-09 公開日 2013-11-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus. Science, 342, 2013
4MMT	Crystal Structure of Prefusion-stabilized RSV F Variant DS-Cav1 at pH 9.5 分子名称: Fusion glycoprotein F1 fused with Fibritin trimerization domain, Fusion glycoprotein F2 著者 Joyce, M.G, Mclellan, J.S, Stewart-Jones, G.B.E, Sastry, M, Yang, Y, Graham, B.S, Kwong, P.D. 登録日 2013-09-09 公開日 2013-11-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus. Science, 342, 2013
4MMQ	Crystal Structure of Prefusion-stabilized RSV F Variant DS 分子名称: Fusion glycoprotein F1 fused with Fibritin trimerization domain, Fusion glycoprotein F2, SULFATE ION 著者 Mclellan, J.S, Joyce, M.G, Stewart-Jones, G.B.E, Sastry, M, Yang, Y, Graham, B.S, Kwong, P.D. 登録日 2013-09-09 公開日 2013-11-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.253 Å) 主引用文献 Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus. Science, 342, 2013
5APH	Ligand complex of RORg LBD 分子名称: DIMETHYL SULFOXIDE, N-(2-FLUOROPHENYL)-4-[(4-FLUOROPHENYL)SULFONYL]-2,3,4,5-TETRAHYDRO-1,4-BENZOXAZEPIN-6-AMINE, NUCLEAR RECEPTOR COACTIVATOR 2, ... 著者 Xue, Y, Aagaard, A, Narjes, F. 登録日 2015-09-16 公開日 2015-11-25 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Benzoxazepines Achieve Potent Suppression of IL-17 Release in Human T-Helper 17 (TH 17) Cells through an Induced-Fit Binding Mode to the Nuclear Receptor ROR gamma. ChemMedChem, 11, 2016
5CBE	E10 in complex with CXCL13 分子名称: 1,2-ETHANEDIOL, C-X-C motif chemokine 13, E10 heavy chain, ... 著者 Tu, C, Bard, J, Mosyak, L. 登録日 2015-06-30 公開日 2015-11-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 A Combination of Structural and Empirical Analyses Delineates the Key Contacts Mediating Stability and Affinity Increases in an Optimized Biotherapeutic Single-chain Fv (scFv). J. Biol. Chem., 291, 2016
4MVI	Crystal structure of an engineered lipocalin (Anticalin US7) in complex with the Alzheimer amyloid peptide Abeta(1-40) 分子名称: Beta-amyloid protein 40, Neutrophil gelatinase-associated lipocalin 著者 Eichinger, A, Skerra, A. 登録日 2013-09-24 公開日 2015-08-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 High-affinity Anticalins with aggregation-blocking activity directed against the Alzheimer beta-amyloid peptide. Biochem.J., 473, 2016
4J9A	Engineered Digoxigenin binder DIG10.3 分子名称: DIGOXIGENIN, Engineered Digoxigenin binder protein DIG10.3 著者 Stoddard, B.L, Doyle, L.A. 登録日 2013-02-15 公開日 2013-06-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Computational design of ligand-binding proteins with high affinity and selectivity. Nature, 501, 2013
4RQS	Crystal structure of fully glycosylated HIV-1 gp120 core bound to CD4 and 17b Fab 分子名称: 17b Fab Heavy Chain, 17b Fab Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Kong, L, Wilson, I.A, Kwong, P.D. 登録日 2014-11-05 公開日 2014-12-31 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (4.493 Å) 主引用文献 Crystal structure of a fully glycosylated HIV-1 gp120 core reveals a stabilizing role for the glycan at Asn262. Proteins, 83, 2015
4Q7D	Wild type Fc (wtFc) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region 著者 Ahmed, A.A, Giddens, J, Pincetic, A, Lomino, J.V, Ravetch, J.V, Wang, L.X, Bjorkman, P.J. 登録日 2014-04-24 公開日 2014-07-23 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structural characterization of anti-inflammatory immunoglobulin g fc proteins. J.Mol.Biol., 426, 2014
4MVK	Crystal structure of an engineered lipocalin (Anticalin US7) in complex with the Alzheimer amyloid peptide fragment VFFAED 分子名称: Amyloid peptide fragment VFFAED, Neutrophil gelatinase-associated lipocalin 著者 Eichinger, A, Skerra, A. 登録日 2013-09-24 公開日 2015-08-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 High-affinity Anticalins with aggregation-blocking activity directed against the Alzheimer beta-amyloid peptide. Biochem.J., 473, 2016
6UCG	Retinoic acid receptor-related orphan receptor (ROR) gamma in complex with allosteric compound 28 分子名称: (3S,4R)-1-[1-(2-chloro-6-cyclopropylbenzene-1-carbonyl)-4-fluoro-1H-indazol-3-yl]-3-hydroxypiperidine-4-carboxylic acid, Nuclear receptor ROR-gamma 著者 Palte, R.L, Parthasarathy, G. 登録日 2019-09-16 公開日 2020-03-04 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.87 Å) 主引用文献 Discovery ofN-(Indazol-3-yl)piperidine-4-carboxylic Acids as ROR gamma t Allosteric Inhibitors for Autoimmune Diseases. Acs Med.Chem.Lett., 11, 2020

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