4PF5

Crystal structure of Concanavalin A complexed with a synthetic derivative of high-mannose chain

Summary for 4PF5

Entry DOI	10.2210/pdb4pf5/pdb
Descriptor	Concanavalin-A, MANGANESE (II) ION, 4-(hydroxymethyl)-1-(alpha-D-mannopyranosyl)-1H-1,2,3-triazole, ... (5 entities in total)
Functional Keywords	sugar binding protein, lectin, high mannose
Biological source	Canavalia ensiformis (Jack bean)
Total number of polymer chains	2
Total formula weight	52111.12
Authors	Lafite, P.,Daniellou, R. (deposition date: 2014-04-28, release date: 2014-12-17, Last modification date: 2024-05-08)
Primary citation	Francois-Heude, M.,Mendez-Ardoy, A.,Cendret, V.,Lafite, P.,Daniellou, R.,Ortiz Mellet, C.,Garcia Fernandez, J.M.,Moreau, V.,Djedaini-Pilard, F. Synthesis of High-Mannose Oligosaccharide Analogues through Click Chemistry: True Functional Mimics of Their Natural Counterparts Against Lectins? Chemistry, 21:1978-1991, 2015 Cited by PubMed: 25483029 DOI: 10.1002/chem.201405481 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.04 Å)

Structure validation