PDB: 19326 件ウェブページステータス検索Chemie searchBIRD

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4DCI	Crystal structure of unknown funciton protein from Synechococcus sp. WH 8102 分子名称: SULFATE ION, uncharacterized protein 著者 Chang, C, Marshall, N, Bearden, J, Palenik, B, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2012-01-17 公開日 2012-02-01 実験手法 X-RAY DIFFRACTION (2.82 Å) 主引用文献 Crystal structure of unknown function protein from Synechococcus sp. WH 8102 To be Published
4DW5	Crystal structure of the glycoprotein Erns from the pestivirus BVDV-1 in complex with a non-cleavable CpU dinucleotide 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E(rns) glycoprotein, ... 著者 Krey, T, Bontems, F, Vonrhein, C, Vaney, M.-C, Bricogne, G, Ruemenapf, T, Rey, F.A. 登録日 2012-02-24 公開日 2012-05-23 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Crystal Structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity. Structure, 20, 2012
8USS	IL17A complexed to Compound 7 分子名称: 4,5-dichloro-N-[(1S)-1-cyclohexyl-2-{[(3S)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]amino}-2-oxoethyl]-1H-pyrrole-2-carboxamide, CHLORIDE ION, Interleukin-17A 著者 Argiriadi, M.A, Ramos, A.L. 登録日 2023-10-29 公開日 2024-04-03 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Discovery of Small Molecule Interleukin 17A Inhibitors with Novel Binding Mode and Stoichiometry: Optimization of DNA-Encoded Chemical Library Hits to In Vivo Active Compounds. J.Med.Chem., 67, 2024
4DWB	Crystal structure of Trypanosoma cruzi farnesyl diphosphate synthase in complex with [2-(n-pentylamino)ethane-1,1-diyl]bisphosphonic acid and Mg2+ 分子名称: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, ACETATE ION, Farnesyl pyrophosphate synthase, ... 著者 Aripirala, S, Amzel, L.M, Gabelli, S.B. 登録日 2012-02-24 公開日 2013-01-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Design, synthesis, calorimetry, and crystallographic analysis of 2-alkylaminoethyl-1,1-bisphosphonates as inhibitors of Trypanosoma cruzi farnesyl diphosphate synthase. J.Med.Chem., 55, 2012
4DES	Crystal Structure of the Wild Type TTR Binding Chrysin (TTRwt:CHR) 分子名称: Transthyretin, chrysin 著者 Trivella, D.B.B, Polikarpov, I. 登録日 2012-01-21 公開日 2012-11-21 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Flavonoid interactions with human transthyretin: Combined structural and thermodynamic analysis. J.Struct.Biol., 180, 2012
8V84	60S ribosome biogenesis intermediate (Dbp10 catalytic structure - Overall map) 分子名称: 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ... 著者 Cruz, V.E, Weirich, C.S, Peddada, N, Erzberger, J.P. 登録日 2023-12-04 公開日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis. Nat Commun, 15, 2024
4DA9	Crystal structure of putative Short-chain dehydrogenase/reductase from Sinorhizobium meliloti 1021 分子名称: SULFATE ION, Short-chain dehydrogenase/reductase 著者 Malashkevich, V.N, Bhosle, R, Toro, R, Seidel, R, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2012-01-12 公開日 2012-01-25 最終更新日 2014-04-02 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of putative Short-chain dehydrogenase/reductase from Sinorhizobium meliloti 1021 To be Published
5U2M	Crystal structure of human NAMPT with A-1293201 分子名称: N-[4-({[(3S)-oxolan-3-yl]methyl}carbamoyl)phenyl]-1,3-dihydro-2H-isoindole-2-carboxamide, Nicotinamide phosphoribosyltransferase, SULFATE ION 著者 Longenecker, K.L, Raich, D, Korepanova, A.V. 登録日 2016-11-30 公開日 2017-06-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Discovery and Characterization of Novel Nonsubstrate and Substrate NAMPT Inhibitors. Mol. Cancer Ther., 16, 2017
4DFN	Crystal structure of spleen tyrosine kinase complexed with an adamantylpyrazine inhibitor 分子名称: 3-amino-6-[3-(1-methyl-1H-pyrazol-4-yl)phenyl]-N-[(1R,2r,3S,5s,7s)-5-hydroxyadamantan-2-yl]pyrazine-2-carboxamide, Tyrosine-protein kinase SYK 著者 Lopez, M, Segarra, V, Vidal, B, Wenzkowski, C, Jestel, A, Krapp, S, Blaesse, M, Nagel, S, Schreiner, P. 登録日 2012-01-24 公開日 2012-04-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Pyrazine-based Syk kinase inhibitors. Bioorg.Med.Chem.Lett., 22, 2012
4DCH	Insights into Glucokinase Activation Mechanism: Observation of Multiple Distinct Protein Conformations 分子名称: (2R)-3-cyclopentyl-2-[4-(methylsulfonyl)phenyl]-N-(1,3-thiazol-2-yl)propanamide, Glucokinase, IODIDE ION, ... 著者 Greasley, S.E, Hickey, M, Feng, J, Garcia, E. 登録日 2012-01-17 公開日 2012-02-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Insights into Mechanism of Glucokinase Activation: OBSERVATION OF MULTIPLE DISTINCT PROTEIN CONFORMATIONS. J.Biol.Chem., 287, 2012
4DDJ	Crystal structure of saposin A in complex with lauryldimethylamine-N-oxide (LDAO) 分子名称: LAURYL DIMETHYLAMINE-N-OXIDE, Saposin-A 著者 Popovic, K, Prive, G.G. 登録日 2012-01-18 公開日 2012-02-15 最終更新日 2020-01-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of saposin A lipoprotein discs. Proc.Natl.Acad.Sci.USA, 109, 2012
4DHQ	Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening 分子名称: (2-{2-[(3-chlorophenyl)amino]-2-oxoethoxy}phenyl)phosphonic acid, 14-3-3 protein sigma, CHLORIDE ION, ... 著者 Thiel, P, Roeglin, L, Kohlbacher, O, Ottmann, C. 登録日 2012-01-30 公開日 2013-07-31 最終更新日 2013-09-04 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Virtual screening and experimental validation reveal novel small-molecule inhibitors of 14-3-3 protein-protein interactions. Chem.Commun.(Camb.), 49, 2013
4DE2	CTX-M-9 class A beta-lactamase complexed with compound 12 分子名称: 3-[(dimethylamino)methyl]-N-[3-(1H-tetrazol-5-yl)phenyl]benzamide, Beta-lactamase, DIMETHYL SULFOXIDE 著者 Nichols, D.A, Chen, Y. 登録日 2012-01-19 公開日 2012-03-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structure-Based Design of Potent and Ligand-Efficient Inhibitors of CTX-M Class A Beta-Lactamase J.Med.Chem., 55, 2012
5UFV	Crystal Structure of a Cellulose-active Polysaccharide Monooxygenase from M. thermophila (MtPMO3*) 分子名称: COPPER (II) ION, Glycoside hydrolase family 61 protein 著者 Span, E.A, Deller, M.C, Marletta, M.A. 登録日 2017-01-05 公開日 2017-03-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 The Role of the Secondary Coordination Sphere in a Fungal Polysaccharide Monooxygenase. ACS Chem. Biol., 12, 2017
4DFH	Crystal structure of cell adhesion molecule nectin-2/CD112 variable domain 分子名称: Poliovirus receptor-related protein 2 著者 Liu, J, Qian, X, Chen, Z, Xu, X, Gao, F, Zhang, S, Zhang, R, Qi, J, Gao, G.F, Yan, J. 登録日 2012-01-23 公開日 2012-06-06 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal Structure of Cell Adhesion Molecule Nectin-2/CD112 and Its Binding to Immune Receptor DNAM-1/CD226 J.Immunol., 188, 2012
4DL6	Human DNA polymerase eta extending primer immediately after cisplatin crosslink (Pt-GG3). 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, Cisplatin, DNA (5'-D(*TP*AP*GP*TP*GP*TP*GP*CP*C)-3'), ... 著者 Zhao, Y, Biertumpfel, C, Gregory, M, Hua, Y, Hanaoka, F, Yang, W. 登録日 2012-02-05 公開日 2012-05-09 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural Basis for Chemoresistance to Cisplatin Mediated by DNA Polymerase eta Proc.Natl.Acad.Sci.USA, 109, 2012
4DLK	Crystal Structure of ATP-Ca++ complex of purK: N5-carboxyaminoimidazole ribonucleotide synthetase 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, PHOSPHATE ION, ... 著者 Fung, L.W, Tuntland, M.L, Santarsiero, B.D, Johnson, M.E. 登録日 2012-02-06 公開日 2013-02-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Elucidation of the bicarbonate binding site and insights into the carboxylation mechanism of (N(5))-carboxyaminoimidazole ribonucleotide synthase (PurK) from Bacillus anthracis. Acta Crystallogr.,Sect.D, 70, 2014
4DGC	TRIMCyp cyclophilin domain from Macaca mulatta: cyclosporin A complex 分子名称: TRIMCyp, cyclosporin A 著者 Caines, M.E.C, Bichel, K, Price, A.J, McEwan, W.A, James, L.C. 登録日 2012-01-25 公開日 2012-02-08 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Diverse HIV viruses are targeted by a conformationally dynamic antiviral. Nat.Struct.Mol.Biol., 19, 2012
4DM1	Contribution of disulfide bond toward thermostability in hyperthermostable endocellulase 分子名称: 458aa long hypothetical endo-1,4-beta-glucanase, PHOSPHATE ION 著者 Kim, H.-W, Ishikawa, K. 登録日 2012-02-06 公開日 2013-02-13 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Contribution of disulfide bond toward thermostability in hyperthermostable endocellulase To be Published
4DGT	Crystal structure of PLP-bound putative aminotransferase from Clostridium difficile 630 crystallized with magnesium formate 分子名称: CHLORIDE ION, MAGNESIUM ION, PYRIDOXAL-5'-PHOSPHATE, ... 著者 Shabalin, I.G, Onopriyenko, O, Kudritska, M, Chruszcz, M, Grimshaw, S, Porebski, P.J, Cooper, D.R, Savchenko, A, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2012-01-26 公開日 2012-02-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Crystal structures of putative aminotransferase from Clostridium difficile 630 to be published
4DND	Crystal structure of syntaxin 10 from Homo sapiens 分子名称: Syntaxin-10 著者 Malashkevich, V.N, Bhosle, R, Toro, R, Seidel, R, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2012-02-08 公開日 2012-02-22 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal structure of syntaxin 10 from Homo sapiens To be Published
4DJ1	Thaumatin I by Langmuir-Blodgett Hanging Drop Method at 1.98A resolution for Unique Water Distribution 分子名称: Thaumatin I 著者 Pechkova, E, Sivozhelezov, V, Belmonte, L, Nicolini, C. 登録日 2012-02-01 公開日 2012-07-18 最終更新日 2012-10-31 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Unique water distribution of Langmuir-Blodgett versus classical crystals. J.Struct.Biol., 180, 2012
4DA2	The structure of Pyrococcus Furiosus SfsA in complex with Ca2+ 分子名称: CALCIUM ION, Sugar fermentation stimulation protein homolog 著者 Baker, P.J, Allen, F.L. 登録日 2012-01-12 公開日 2014-10-15 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The structure of SfsA and its DNA complex; A DNA/RNA nuclease with a novel domain combination To be Published
4DJN	Crystal structure of a ribonucleotide reductase M2 B (RNRR2) from Homo sapiens at 2.20 A resolution 分子名称: 1,2-ETHANEDIOL, Ribonucleoside-diphosphate reductase subunit M2 B, SULFATE ION 著者 Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL) 登録日 2012-02-02 公開日 2012-05-09 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of a ribonucleotide reductase M2 B (RNRR2) from Homo sapiens at 2.20 A resolution To be published
8V85	60S ribosome biogenesis intermediate (Dbp10 catalytic structure - Low-pass filtered locally refined map) 分子名称: ATP-dependent RNA helicase DBP10 著者 Cruz, V.E, Weirich, C.S, Peddada, N, Erzberger, J.P. 登録日 2023-12-04 公開日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis. Nat Commun, 15, 2024

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