Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

1LP9
DownloadVisualize
BU of 1lp9 by Molmil
Xenoreactive complex AHIII 12.2 TCR bound to p1049/HLA-A2.1
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
著者Buslepp, J, Wang, H, Biddison, W.E, Appella, E, Collins, E.J.
登録日2002-05-07
公開日2003-11-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A correlation between TCR Valpha docking on MHC and CD8 dependence: implications for T cell selection.
Immunity, 19, 2003
1LO0
DownloadVisualize
BU of 1lo0 by Molmil
Catalytic Retro-Diels-Alderase Transition State Analogue Complex
分子名称: 3-{[(9-CYANO-9,10-DIHYDRO-10-METHYLACRIDIN-9-YL)CARBONYL]AMINO}PROPANOIC ACID, If kappa light chain, Ig gamma 2a heavy chain
著者Hugot, M, Reymond, J.L, Baumann, U.
登録日2002-05-05
公開日2002-06-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A structural basis for the activity of retro-Diels-Alder catalytic antibodies: evidence for a catalytic aromatic residue.
Proc.Natl.Acad.Sci.USA, 99, 2002
1VGE
DownloadVisualize
BU of 1vge by Molmil
TR1.9 FAB FRAGMENT OF A HUMAN IGG1 KAPPA AUTOANTIBODY
分子名称: TR1.9 FAB
著者Chacko, S, Padlan, E.A.
登録日1996-01-04
公開日1996-06-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural studies of human autoantibodies. Crystal structure of a thyroid peroxidase autoantibody Fab.
J.Biol.Chem., 271, 1996
3PV7
DownloadVisualize
BU of 3pv7 by Molmil
Crystal structure of NKp30 ligand B7-H6
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ig-like domain-containing protein DKFZp686O24166/DKFZp686I21167
著者Li, Y.
登録日2010-12-06
公開日2011-03-16
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the activating natural killer cell receptor NKp30 bound to its ligand B7-H6 reveals basis for tumor cell recognition in humans
to be published
1T1Y
DownloadVisualize
BU of 1t1y by Molmil
Structural basis for degenerate recognition of HIV peptide variants by cytotoxic lymphocyte, variant SL9-5V
分子名称: Beta-2-microglobulin, GAG PEPTIDE, HLA class I histocompatibility antigen, ...
著者Martinez-Hackert, E, Anikeeva, N, Kalams, S.A, Walker, B.D, Hendrickson, W.A, Sykulev, Y.
登録日2004-04-19
公開日2005-09-06
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis for Degenerate Recognition of Natural HIV Peptide Variants by Cytotoxic Lymphocytes.
J.Biol.Chem., 281, 2006
4JVW
DownloadVisualize
BU of 4jvw by Molmil
IgM C4-domain from mouse
分子名称: Ig mu chain C region secreted form
著者Mueller, R, Graewert, A.M, Kern, T, Madl, T, Peschek, J, Sattler, M, Groll, M, Buchner, J.
登録日2013-03-26
公開日2013-06-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献High-resolution structures of the IgM Fc domains reveal principles of its hexamer formation.
Proc.Natl.Acad.Sci.USA, 110, 2013
5VWJ
DownloadVisualize
BU of 5vwj by Molmil
HLA-B*58:01 presenting LTVQVARVW
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-58 alpha chain, ...
著者Pymm, P, Rossjohn, J, Vivian, J.P.
登録日2017-05-22
公開日2018-10-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome.
Nat Commun, 9, 2018
2QRI
DownloadVisualize
BU of 2qri by Molmil
Crystal structure of a single chain trimer composed of the MHC I heavy chain H-2Kb WT, beta-2microglobulin, and ovalbumin-derived peptide.
分子名称: H-2 class I histocompatibility antigen K-B alpha chain, Beta-2 microglobulin, ovalbumin-derived peptide
著者Mitaksov, V.E, Fremont, D.H.
登録日2007-07-28
公開日2007-11-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural engineering of pMHC reagents for T cell vaccines and diagnostics.
Chem.Biol., 14, 2007
1D5Z
DownloadVisualize
BU of 1d5z by Molmil
X-RAY CRYSTAL STRUCTURE OF HLA-DR4 COMPLEXED WITH PEPTIDOMIMETIC AND SEB
分子名称: PROTEIN (ENTEROTOXIN TYPE B), PROTEIN (HLA CLASS II HISTOCOMPATIBILITY ANTIGEN), PROTEIN (PEPTIDOMIMETIC INHIBITOR)
著者Swain, A, Crowther, R, Kammlott, U.
登録日1999-10-12
公開日2000-06-28
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Peptide and peptide mimetic inhibitors of antigen presentation by HLA-DR class II MHC molecules. Design, structure-activity relationships, and X-ray crystal structures.
J.Med.Chem., 43, 2000
1DQJ
DownloadVisualize
BU of 1dqj by Molmil
CRYSTAL STRUCTURE OF THE ANTI-LYSOZYME ANTIBODY HYHEL-63 COMPLEXED WITH HEN EGG WHITE LYSOZYME
分子名称: ANTI-LYSOZYME ANTIBODY HYHEL-63 (HEAVY CHAIN), ANTI-LYSOZYME ANTIBODY HYHEL-63 (LIGHT CHAIN), LYSOZYME
著者Li, H, Mariuzza, R.A.
登録日2000-01-04
公開日2000-01-19
最終更新日2021-07-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Three-dimensional structures of the free and antigen-bound Fab from monoclonal antilysozyme antibody HyHEL-63(,).
Biochemistry, 39, 2000
2QHR
DownloadVisualize
BU of 2qhr by Molmil
Crystal structure of the 13F6-1-2 Fab fragment bound to its Ebola virus glycoprotein peptide epitope.
分子名称: 13F6-1-2 Fab fragment V lambda x light chain, 13F6-1-2 Fab fragment heavy chain, Envelope glycoprotein peptide
著者Lee, J.E, Kuehne, A, Abelson, D.M, Fusco, M.L, Hart, M.K, Saphire, E.O.
登録日2007-07-02
公開日2008-01-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Complex of a protective antibody with its Ebola virus GP peptide epitope: unusual features of a V lambda x light chain.
J.Mol.Biol., 375, 2008
2QRS
DownloadVisualize
BU of 2qrs by Molmil
Crystal Structure of a single chain trimer composed of the MHC I heavy chain H-2Kb Y84A, beta-2microglobulin, and ovalbumin-derived peptide.
分子名称: H-2 class I histocompatibility antigen K-B alpha chain, Beta-2 microglobulin, ovalbumin-derived peptide
著者Mitaksov, V.E, Fremont, D.H.
登録日2007-07-29
公開日2007-11-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural engineering of pMHC reagents for T cell vaccines and diagnostics.
Chem.Biol., 14, 2007
3H9H
DownloadVisualize
BU of 3h9h by Molmil
Human Class I MHC HLA-A2(A150P) in complex with the Tel1p peptide
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2009-04-30
公開日2010-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility.
Immunity, 31, 2009
3U0W
DownloadVisualize
BU of 3u0w by Molmil
AD related murine antibody Fragment
分子名称: Fab Heavy Chain, Ig gamma-1 chain C region, Fab Light Chain, ...
著者Miles, L.A, Crespi, G.A.N, Parker, M.W.
登録日2011-09-29
公開日2012-10-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of an AD related antibody
To be Published
5V5L
DownloadVisualize
BU of 5v5l by Molmil
Crystal structure of HLA-B*5801 complex with HIV-1 gag derived peptide TW10
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-58 alpha chain, ...
著者Li, X, Wang, J.-H.
登録日2017-03-14
公開日2017-06-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.002 Å)
主引用文献Crystal structure of HLA-B*5801 with a TW10 HIV Gag epitope reveals a novel mode of peptide presentation.
Cell. Mol. Immunol., 14, 2017
3RWI
DownloadVisualize
BU of 3rwi by Molmil
Rhesus macaque MHC class I molecule Mamu-B*17-GW10
分子名称: Beta-2-microglobulin, Major histocompatibility complex class I, Vif GW10 peptide from Virion infectivity factor
著者Wu, Y, Gao, F, Liu, J, Qi, J.X, Price, D.A, Gao, G.F.
登録日2011-05-09
公開日2012-03-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.009 Å)
主引用文献Structural basis of diverse peptide accommodation by the rhesus macaque MHC class I molecule Mamu-B*17: insights into immune protection from simian immunodeficiency virus
J.Immunol., 187, 2011
6Z9V
DownloadVisualize
BU of 6z9v by Molmil
Human Class I Major Histocompatibility Complex, A02 allele, presenting IIGWMWIPV
分子名称: 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, ...
著者Rizkallah, P.J, Man, S, Redman, J.E.
登録日2020-06-04
公開日2021-06-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Synthetic Peptides with Inadvertent Chemical Modifications Can Activate Potentially Autoreactive T Cells.
J Immunol., 207, 2021
5TR8
DownloadVisualize
BU of 5tr8 by Molmil
Crystal structure of vaccine-elicited pan- influenza H1N1 neutralizing murine antibody 441D6.
分子名称: 441D6 Fab Heavy chain, 441D6 Fab Light chain, NICKEL (II) ION
著者Joyce, M.G, Kanekiyo, M, Mascola, J.R, Graham, B.S, Kwong, P.D.
登録日2016-10-25
公開日2018-05-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses.
Nat.Immunol., 20, 2019
6ULN
DownloadVisualize
BU of 6uln by Molmil
Molecular basis for tumor infiltrating TCR recognition of hotspot KRAS-G12D mutation
分子名称: Beta-2-microglobulin, GLY-ALA-ASP-GLY-VAL-GLY-LYS-SER-ALA, GLYCEROL, ...
著者Sun, P.D, Sim, M.J.W.
登録日2019-10-08
公開日2020-05-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献High-affinity oligoclonal TCRs define effective adoptive T cell therapy targeting mutant KRAS-G12D.
Proc.Natl.Acad.Sci.USA, 117, 2020
5VKK
DownloadVisualize
BU of 5vkk by Molmil
Crystal structure of Fab fragment of anti-CD22 Epratuzumab
分子名称: Epratuzumab Fab Heavy Chain, Epratuzumab Fab Light Chain
著者Sicard, T, Ereno-Orbea, J, Julien, J.P.
登録日2017-04-21
公開日2017-10-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.014 Å)
主引用文献Molecular basis of human CD22 function and therapeutic targeting.
Nat Commun, 8, 2017
8G8D
DownloadVisualize
BU of 8g8d by Molmil
Crystal structure of DH1346 Fab in complex with HIV proximal MPER peptide
分子名称: DH1346 heavy chain, DH1346 light chain, FLUORIDE ION, ...
著者Niyongabo, A, Janus, B.M, Ofek, G.
登録日2023-02-17
公開日2024-05-22
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Vaccine induction of heterologous HIV-1-neutralizing antibody B cell lineages in humans.
Cell, 187, 2024
7ZT4
DownloadVisualize
BU of 7zt4 by Molmil
Structure of E8 TCR in complex with human MR1 bound to 6FP
分子名称: 2-azanyl-6-methyl-3~{H}-pteridin-4-one, Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, ...
著者Karuppiah, V, Robinson, R.A.
登録日2022-05-09
公開日2023-06-28
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses.
J.Exp.Med., 220, 2023
3WE6
DownloadVisualize
BU of 3we6 by Molmil
Crystal structure of anti-Prostaglandin E2 Fab fragment
分子名称: ISOPROPYL ALCOHOL, mAb Fab H fragment, mAb Fab L fragment
著者Sugahara, M, Ago, H, Saino, H, Miyano, M.
登録日2013-07-01
公開日2014-07-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Crystal structure of anti-Prostaglandin E2 Fab fragment with Prostaglandin E2
To be Published
5EU6
DownloadVisualize
BU of 5eu6 by Molmil
HLA Class I antigen
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Rizkallah, P.J, Bianchi, V, Cole, D.K, Sewell, A.K.
登録日2015-11-18
公開日2016-03-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献A Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen.
J.Biol.Chem., 291, 2016
7KP1
DownloadVisualize
BU of 7kp1 by Molmil
CD1a-42:2 SM binary complex
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-2-microglobulin, T-cell surface glycoprotein CD1a, ...
著者Wegrecki, M, Le Nours, J, Rossjohn, J.
登録日2020-11-10
公開日2021-05-05
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献CD1a selectively captures endogenous cellular lipids that broadly block T cell response.
J.Exp.Med., 218, 2021

223790

件を2024-08-14に公開中

PDB statisticsPDBj update infoContact PDBjnumon