PDB: 2901 件ウェブページステータス検索Chemie searchBIRD

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3WUW	KIR3DL1 in complex with HLA-B*57:01.I80T 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... 著者 Vivian, J.P, Rossjohn, J. 登録日 2014-05-06 公開日 2014-05-28 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Mutational and structural analysis of KIR3DL1 reveals a lineage-defining allotypic dimorphism that impacts both HLA and peptide sensitivity J.Immunol., 192, 2014
1T0M	Conformational switch in polymorphic H-2K molecules containing an HSV peptide 分子名称: Beta-2-microglobulin, Glycoprotein B, H-2 class I histocompatibility antigen, ... 著者 Webb, A.I, Borg, N.A, Dunstone, M.A, Kjer-Nielsen, L, Beddoe, T, McCluskey, J, Carbone, F.R, Bottomley, S.P, Purcell, A.W, Rossjohn, J. 登録日 2004-04-12 公開日 2004-11-23 最終更新日 2019-11-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The structure of H-2K(b) and K(bm8) complexed to a herpes simplex virus determinant: evidence for a conformational switch that governs T cell repertoire selection and viral resistance. J Immunol., 173, 2004
3X14	Crystal structure of HLA-B*0801.N80I.R82L.G83R 分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-8 alpha chain, ... 著者 Vivian, J.P, Rossjohn, J. 登録日 2014-10-25 公開日 2014-12-24 最終更新日 2015-04-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The interaction of KIR3DL1*001 with HLA class I molecules is dependent upon molecular microarchitecture within the Bw4 epitope J.Immunol., 194, 2015
2IQA	PFA2 FAB fragment, monoclinic apo form 分子名称: ACETAMIDE, CHLORIDE ION, GLYCEROL, ... 著者 Gardberg, A.S, Dealwis, C. 登録日 2006-10-13 公開日 2007-10-09 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Molecular basis for passive immunotherapy of Alzheimer's disease Proc.Natl.Acad.Sci.Usa, 104, 2007
5V5L	Crystal structure of HLA-B*5801 complex with HIV-1 gag derived peptide TW10 分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-58 alpha chain, ... 著者 Li, X, Wang, J.-H. 登録日 2017-03-14 公開日 2017-06-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.002 Å) 主引用文献 Crystal structure of HLA-B*5801 with a TW10 HIV Gag epitope reveals a novel mode of peptide presentation. Cell. Mol. Immunol., 14, 2017
3RWI	Rhesus macaque MHC class I molecule Mamu-B*17-GW10 分子名称: Beta-2-microglobulin, Major histocompatibility complex class I, Vif GW10 peptide from Virion infectivity factor 著者 Wu, Y, Gao, F, Liu, J, Qi, J.X, Price, D.A, Gao, G.F. 登録日 2011-05-09 公開日 2012-03-21 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.009 Å) 主引用文献 Structural basis of diverse peptide accommodation by the rhesus macaque MHC class I molecule Mamu-B*17: insights into immune protection from simian immunodeficiency virus J.Immunol., 187, 2011
5TR8	Crystal structure of vaccine-elicited pan- influenza H1N1 neutralizing murine antibody 441D6. 分子名称: 441D6 Fab Heavy chain, 441D6 Fab Light chain, NICKEL (II) ION 著者 Joyce, M.G, Kanekiyo, M, Mascola, J.R, Graham, B.S, Kwong, P.D. 登録日 2016-10-25 公開日 2018-05-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses. Nat.Immunol., 20, 2019
6Z9V	Human Class I Major Histocompatibility Complex, A02 allele, presenting IIGWMWIPV 分子名称: 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, ... 著者 Rizkallah, P.J, Man, S, Redman, J.E. 登録日 2020-06-04 公開日 2021-06-30 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Synthetic Peptides with Inadvertent Chemical Modifications Can Activate Potentially Autoreactive T Cells. J Immunol., 207, 2021
6ULN	Molecular basis for tumor infiltrating TCR recognition of hotspot KRAS-G12D mutation 分子名称: Beta-2-microglobulin, GLY-ALA-ASP-GLY-VAL-GLY-LYS-SER-ALA, GLYCEROL, ... 著者 Sun, P.D, Sim, M.J.W. 登録日 2019-10-08 公開日 2020-05-27 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 High-affinity oligoclonal TCRs define effective adoptive T cell therapy targeting mutant KRAS-G12D. Proc.Natl.Acad.Sci.USA, 117, 2020
5VKK	Crystal structure of Fab fragment of anti-CD22 Epratuzumab 分子名称: Epratuzumab Fab Heavy Chain, Epratuzumab Fab Light Chain 著者 Sicard, T, Ereno-Orbea, J, Julien, J.P. 登録日 2017-04-21 公開日 2017-10-04 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.014 Å) 主引用文献 Molecular basis of human CD22 function and therapeutic targeting. Nat Commun, 8, 2017
7ZT4	Structure of E8 TCR in complex with human MR1 bound to 6FP 分子名称: 2-azanyl-6-methyl-3~{H}-pteridin-4-one, Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, ... 著者 Karuppiah, V, Robinson, R.A. 登録日 2022-05-09 公開日 2023-06-28 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses. J.Exp.Med., 220, 2023
7KP1	CD1a-42:2 SM binary complex 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-2-microglobulin, T-cell surface glycoprotein CD1a, ... 著者 Wegrecki, M, Le Nours, J, Rossjohn, J. 登録日 2020-11-10 公開日 2021-05-05 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 CD1a selectively captures endogenous cellular lipids that broadly block T cell response. J.Exp.Med., 218, 2021
3WE6	Crystal structure of anti-Prostaglandin E2 Fab fragment 分子名称: ISOPROPYL ALCOHOL, mAb Fab H fragment, mAb Fab L fragment 著者 Sugahara, M, Ago, H, Saino, H, Miyano, M. 登録日 2013-07-01 公開日 2014-07-02 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Crystal structure of anti-Prostaglandin E2 Fab fragment with Prostaglandin E2 To be Published
5EU6	HLA Class I antigen 分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... 著者 Rizkallah, P.J, Bianchi, V, Cole, D.K, Sewell, A.K. 登録日 2015-11-18 公開日 2016-03-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 A Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen. J.Biol.Chem., 291, 2016
3V7M	Crystal structure of monoclonal human anti-Rhesus D Fc IgG1 T125(YB2/0) in the presence of Zn2+ 分子名称: GLYCEROL, IMIDAZOLE, Ig gamma-1 chain C region, ... 著者 Menez, R, Stura, E.A, Bourel, D, Siberil, S, Jorieux, S, De Romeuf, C, Ducancel, F, Fridman, W.H, Teillaud, J.L. 登録日 2011-12-21 公開日 2012-02-22 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Effect of zinc on human IgG1 and its Fc gamma R interactions. Immunol.Lett., 143, 2012
6AVF	Crystal structure of the KFJ5 TCR-NY-ESO-1-HLA-B*07:02 complex 分子名称: ALA-PRO-ARG-GLY-PRO-HIS-GLY-GLY-ALA-ALA-SER-GLY-LEU, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... 著者 Gully, B.S, Gras, S, Rossjohn, J. 登録日 2017-09-02 公開日 2018-02-28 最終更新日 2019-04-17 実験手法 X-RAY DIFFRACTION (2.028 Å) 主引用文献 Divergent T-cell receptor recognition modes of a HLA-I restricted extended tumour-associated peptide. Nat Commun, 9, 2018
6DFX	human diabetogenic TCR T1D3 in complex with DQ8-p8E9E peptide 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Wang, Y, Dai, S. 登録日 2018-05-15 公開日 2019-04-17 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes. Sci Immunol, 4, 2019
8HSW	CRYSTAL STRUCTURE OF BAT MHC CLASS I MYLU-B-67 FOR 2.1 ANGSTROM 分子名称: Beta-2-microglobulin, Ig-like domain-containing protein, THR-PRO-GLN-SER-ALA-PRO-HIS-GLY-VAL 著者 Wang, S.Q, Zhang, N.Z. 登録日 2022-12-20 公開日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 CRYSTAL STRUCTURE OF BAT MHC CLASS I MYLU-B-67 FOR 2.1 ANGSTROM To Be Published
1FE8	CRYSTAL STRUCTURE OF THE VON WILLEBRAND FACTOR A3 DOMAIN IN COMPLEX WITH A FAB FRAGMENT OF IGG RU5 THAT INHIBITS COLLAGEN BINDING 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CACODYLATE ION, IMMUNOGLOBULIN IGG RU5, ... 著者 Bouma, B, Huizinga, E.G, Schiphorst, M.E, Sixma, J.J, Kroon, J, Gros, P. 登録日 2000-07-21 公開日 2001-04-04 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Identification of the collagen-binding site of the von Willebrand factor A3-domain. J.Biol.Chem., 276, 2001
5HHN	Crystal Structure of HLA-A*0201 in complex with M1-F5L 分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... 著者 Gras, S, Josephs, T.M, Rossjohn, J. 登録日 2016-01-11 公開日 2016-03-23 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Molecular basis for universal HLA-A*0201-restricted CD8+ T-cell immunity against influenza viruses. Proc.Natl.Acad.Sci.USA, 113, 2016
5C0B	1E6 TCR in complex with HLA-A02 carrying RQFGPDFPTI 分子名称: 1,2-ETHANEDIOL, 1E6 TCR Alpha Chain, 1E6 TCR Beta Chain, ... 著者 Rizkallah, P.J, Bulek, A.M, Cole, D.K, Sewell, A.K. 登録日 2015-06-12 公開日 2016-05-04 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity. J.Clin.Invest., 126, 2016
3FON	Crystal structure of the Class I MHC Molecule H-2Kwm7 with a Single Self Peptide VNDIFEAI 分子名称: Beta-2-microglobulin, MHC, Peptide 著者 Malashkevich, V.N, Qian, J, Jarchum, I, Yamada, T, Mikesh, L, Palmieri, E, Lund, T, Hattori, M, Shabanowitz, J, Hunt, D.F, Ramagopal, U.A, Brims, D.R, Almo, S.C, Nathenson, S.G, DiLorenzo, T.P. 登録日 2008-12-30 公開日 2010-01-12 最終更新日 2020-02-05 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Predominant occupation of the class I MHC molecule H-2Kwm7 with a single self-peptide suggests a mechanism for its diabetes-protective effect. Int.Immunol., 22, 2010
5YXN	A T cell receptor in complex with HLA-A0201 restricted Hepatitis C virus NS3 peptide (KLVALGINAV) 分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... 著者 Hui, F. 登録日 2017-12-06 公開日 2018-12-12 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Capturing HCV immune escape by targeting structural based mechanism To Be Published
6D2B	HLA-B*57:01 presenting LSDSTARDVTW 分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-57 alpha chain, ... 著者 Vivian, J.P, Rossjohn, J. 登録日 2018-04-13 公開日 2018-10-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 A subset of HLA-I peptides are not genomically templated: Evidence for cis- and trans-spliced peptide ligands. Sci Immunol, 3, 2018
7PBC	Crystal structure of engineered TCR (796) complexed to HLA-A*02:01 presenting MAGE-A10 9-mer peptide 分子名称: Beta-2-microglobulin, CHLORIDE ION, GLYCEROL, ... 著者 Simister, P.C, Border, E.C, Vieira, J.F, Pumphrey, N.J. 登録日 2021-08-02 公開日 2022-08-03 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Structural insights into engineering a T-cell receptor targeting MAGE-A10 with higher affinity and specificity for cancer immunotherapy. J Immunother Cancer, 10, 2022

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