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7FUC
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BU of 7fuc by Molmil
Crystal Structure of human cyclic GMP-AMP synthase in complex with 6-(2-chloro-4-methylphenyl)-2-(morpholin-4-ylmethyl)-1H-benzimidazole-4-carboxylic acid
分子名称: (6M)-6-(2-chloro-4-methylphenyl)-2-[(morpholin-4-yl)methyl]-1H-benzimidazole-4-carboxylic acid, Cyclic GMP-AMP synthase, ZINC ION
著者Leibrock, L, Benz, J, Groebke-Zbinden, K, Galley, G, Rudolph, M.G.
登録日2023-02-08
公開日2024-02-21
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Crystal Structure of a human cyclic GMP-AMP synthase complex
To be published
7FUE
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Crystal Structure of human cyclic GMP-AMP synthase in complex with 2-[[2-chloro-5-(1-methylpyrazol-3-yl)phenyl]methylamino]-5-(2-phenylethyl)-4H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
分子名称: (8S)-2-({[(5P)-2-chloro-5-(1-methyl-1H-pyrazol-3-yl)phenyl]methyl}amino)-5-(2-phenylethyl)[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one, Cyclic GMP-AMP synthase, ZINC ION
著者Leibrock, L, Benz, J, Groebke-Zbinden, K, Rudolph, M.G.
登録日2023-02-08
公開日2024-02-21
実験手法X-RAY DIFFRACTION (2.169 Å)
主引用文献Crystal Structure of a human cyclic GMP-AMP synthase complex
To be published
7FUD
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BU of 7fud by Molmil
Crystal Structure of human cyclic GMP-AMP synthase in complex with 5-benzyl-2-[[2-chloro-5-(1-methylpyrazol-3-yl)phenyl]methylamino]-4H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
分子名称: (8S)-5-benzyl-2-({[(5P)-2-chloro-5-(1-methyl-1H-pyrazol-3-yl)phenyl]methyl}amino)[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one, Cyclic GMP-AMP synthase, ZINC ION
著者Leibrock, L, Benz, J, Groebke-Zbinden, K, Rudolph, M.G.
登録日2023-02-08
公開日2024-02-21
実験手法X-RAY DIFFRACTION (2.026 Å)
主引用文献Crystal Structure of a human cyclic GMP-AMP synthase complex
To be published
7FU1
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BU of 7fu1 by Molmil
Crystal Structure of human cyclic GMP-AMP synthase in complex with 5-[3-[[(5-bromo-2-hydroxybenzoyl)amino]methyl]phenyl]-2-methylpyrazole-3-carboxylic acid
分子名称: (3P)-3-{3-[(5-bromo-2-hydroxybenzamido)methyl]phenyl}-1-methyl-1H-pyrazole-5-carboxylic acid, Cyclic GMP-AMP synthase, ZINC ION
著者Leibrock, L, Benz, J, Groebke-Zbinden, K, Rudolph, M.G.
登録日2023-02-08
公開日2024-02-21
実験手法X-RAY DIFFRACTION (2.074 Å)
主引用文献Crystal Structure of a human cyclic GMP-AMP synthase complex
To be published
7FUP
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BU of 7fup by Molmil
Crystal Structure of human cyclic GMP-AMP synthase in complex with methyl 1-benzoyl-3-methyl-5-(1,2-oxazol-5-yl)pyrazole-4-carboxylate
分子名称: Cyclic GMP-AMP synthase, PROPANOIC ACID, ZINC ION
著者Leibrock, L, Benz, J, Groebke-Zbinden, K, Rudolph, M.G.
登録日2023-02-08
公開日2024-02-21
実験手法X-RAY DIFFRACTION (2.411 Å)
主引用文献Crystal Structure of a human cyclic GMP-AMP synthase complex
To be published
5SXO
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BU of 5sxo by Molmil
1.35 angstrom resolution crystal structure of beta-ketoacyl-ACP synthase II (FabF) from Listeria monocytogenes
分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2
著者Soares da Costa, T.P, Nanson, J.D, Forwood, J.K.
登録日2016-08-09
公開日2016-11-02
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献1.35 angstrom resolution crystal structure of beta-ketoacyl-ACP synthase II (FabF) from Listeria monocytogenes
To Be Published
4D2I
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BU of 4d2i by Molmil
Crystal structure of the HerA hexameric DNA translocase from Sulfolobus solfataricus bound to AMP-PNP
分子名称: HERA, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Rzechorzek, N.J, Blackwood, J.K, Bray, S.M, Maman, J.D, Pellegrini, L, Robinson, N.P.
登録日2014-05-09
公開日2014-12-03
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.841 Å)
主引用文献Structure of the Hexameric Hera ATPase Reveals a Mechanism of Translocation-Coupled DNA-End Processing in Archaea
Nat.Commun., 5, 2014
7FTX
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Crystal Structure of apo human cyclic GMP-AMP synthase - hexagonal form
分子名称: Cyclic GMP-AMP synthase, SULFATE ION, ZINC ION
著者Leibrock, L, Benz, J, Groebke-Zbinden, K, Rudolph, M.G.
登録日2023-02-08
公開日2024-02-21
実験手法X-RAY DIFFRACTION (2.831 Å)
主引用文献Crystal Structure of a human cyclic GMP-AMP synthase complex
To be published
1J1Z
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BU of 1j1z by Molmil
Crystal Structure of Thermus thermophilus HB8 Argininosuccinate Synthetase in complex with substrate
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ASPARTIC ACID, Argininosuccinate Synthetase, ...
著者Goto, M, Hirotsu, K, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2002-12-24
公開日2003-04-22
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structures of argininosuccinate synthetase in enzyme-ATP-substrates and enzyme-AMP-product forms
J.Biol.Chem., 278, 2003
3A4I
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BU of 3a4i by Molmil
Crystal structure of GMP synthetase PH1347 from Pyrococcus horikoshii OT3
分子名称: GMP synthase [glutamine-hydrolyzing] subunit B
著者Maruoka, S, Horita, S, Lee, W.C, Nagata, K, Tanokura, M.
登録日2009-07-07
公開日2009-07-21
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Crystal structure of the ATPPase subunit and its substrate-dependent association with the GATase Subunit: a novel regulatory mechanism for a two-subunit-type GMP synthetase from Pyrococcus horikoshii OT3.
J.Mol.Biol., 395, 2010
4EKK
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BU of 4ekk by Molmil
Akt1 with AMP-PNP
分子名称: Glycogen synthase kinase-3 beta, MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Wu, W.-I, Vigers, G.P.A, Morales, T.H, Brandhuber, B.J.
登録日2012-04-09
公開日2012-05-23
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献An ATP-Site On-Off Switch That Restricts Phosphatase Accessibility of Akt.
Sci.Signal., 5, 2012
1DTS
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BU of 1dts by Molmil
CRYSTAL STRUCTURE OF AN ATP DEPENDENT CARBOXYLASE, DETHIOBIOTIN SYNTHASE, AT 1.65 ANGSTROMS RESOLUTION
分子名称: DETHIOBIOTIN SYNTHETASE
著者Huang, W, Lindqvist, Y, Schneider, G.
登録日1995-03-28
公開日1995-04-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structure of an ATP-dependent carboxylase, dethiobiotin synthetase, at 1.65 A resolution.
Structure, 2, 1994
7LJ9
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BU of 7lj9 by Molmil
Structure of human ATP citrate lyase in complex with acetyl-CoA and oxaloacetate
分子名称: ACETYL COENZYME *A, ATP-citrate synthase, OXALOACETATE ION
著者Wei, X, Marmorstein, R.
登録日2021-01-28
公開日2021-03-31
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Reply to: Acetyl-CoA is produced by the citrate synthase homology module of ATP-citrate lyase.
Nat.Struct.Mol.Biol., 28, 2021
3KJG
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BU of 3kjg by Molmil
ADP-bound state of CooC1
分子名称: ADENOSINE-5'-DIPHOSPHATE, CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC
著者Jeoung, J.-H, Dobbek, H.
登録日2009-11-03
公開日2010-01-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of the ATP-Dependent Maturation Factor of Ni,Fe-Containing Carbon Monoxide Dehydrogenases
J.Mol.Biol., 396, 2010
3KJH
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Zn-bound state of CooC1
分子名称: CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC, ZINC ION
著者Jeoung, J.-H, Dobbek, H.
登録日2009-11-03
公開日2010-01-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of the ATP-Dependent Maturation Factor of Ni,Fe-Containing Carbon Monoxide Dehydrogenases
J.Mol.Biol., 396, 2010
6Z2H
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BU of 6z2h by Molmil
Citryl-CoA lyase module of human ATP citrate lyase in complex with (3S)-citryl-CoA.
分子名称: (3S)-citryl-Coenzyme A, ACETYL COENZYME *A, ATP-citrate synthase, ...
著者Verschueren, K.H.G, Verstraete, K.
登録日2020-05-15
公開日2021-05-26
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Acetyl-CoA is produced by the citrate synthase homology module of ATP-citrate lyase.
Nat.Struct.Mol.Biol., 28, 2021
7LLA
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BU of 7lla by Molmil
Structure of human ATP citrate lyase in complex with acetyl-CoA and oxaloacetate (EM map was generated in Cryosparc with non-uniform refinement)
分子名称: ACETYL COENZYME *A, ATP-citrate synthase, OXALOACETATE ION
著者Wei, X, Marmorstein, R.
登録日2021-02-03
公開日2021-03-03
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Reply to: Acetyl-CoA is produced by the citrate synthase homology module of ATP-citrate lyase.
Nat.Struct.Mol.Biol., 28, 2021
7LIW
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BU of 7liw by Molmil
Local refinement of human ATP citrate lyase E599Q mutant ASH domain
分子名称: (2S)-2-hydroxy-2-[2-oxo-2-(phosphonooxy)ethyl]butanedioic acid, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ...
著者Wei, X, Marmorstein, R.
登録日2021-01-28
公開日2021-05-19
最終更新日2025-06-04
実験手法ELECTRON MICROSCOPY (2.85 Å)
主引用文献Reply to: Acetyl-CoA is produced by the citrate synthase homology module of ATP-citrate lyase.
Nat.Struct.Mol.Biol., 28, 2021
3KJE
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BU of 3kje by Molmil
Empty state of CooC1
分子名称: CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC
著者Jeoung, J.-H, Dobbek, H.
登録日2009-11-03
公開日2010-01-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of the ATP-Dependent Maturation Factor of Ni,Fe-Containing Carbon Monoxide Dehydrogenases
J.Mol.Biol., 396, 2010
3KJI
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BU of 3kji by Molmil
Zn and ADP bound state of CooC1
分子名称: ADENOSINE-5'-DIPHOSPHATE, CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC, ...
著者Jeoung, J.-H, Dobbek, H.
登録日2009-11-03
公開日2010-01-19
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Crystal Structure of the ATP-Dependent Maturation Factor of Ni,Fe-Containing Carbon Monoxide Dehydrogenases
J.Mol.Biol., 396, 2010
1KUT
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BU of 1kut by Molmil
Structural Genomics, Protein TM1243, (SAICAR synthetase)
分子名称: Phosphoribosylaminoimidazole-succinocarboxamide synthase
著者Zhang, R, Skarina, T, Beasley, S, Edwards, A, Joachimiak, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG)
登録日2002-01-22
公開日2002-08-14
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of SAICAR synthase from Thermotoga maritima at 2.2 angstroms reveals an unusual covalent dimer.
Acta Crystallogr.,Sect.F, 62, 2006
1Q3D
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BU of 1q3d by Molmil
GSK-3 Beta complexed with Staurosporine
分子名称: GLYCOGEN SYNTHASE KINASE-3 BETA, STAUROSPORINE
著者Bertrand, J.A, Thieffine, S, Vulpetti, A, Cristiani, C, Valsasina, B, Knapp, S, Kalisz, H.M, Flocco, M.
登録日2003-07-29
公開日2003-10-21
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Characterization of the Gsk-3Beta Active Site Using Selective and Non-selective ATP-Mimetic Inhibitors
J.Mol.Biol., 333, 2003
1PYX
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BU of 1pyx by Molmil
GSK-3 Beta complexed with AMP-PNP
分子名称: Glycogen synthase kinase-3 beta, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Bertrand, J.A, Thieffine, S, Vulpetti, A, Cristiani, C, Valsasina, B, Knapp, S, Kalisz, H.M, Flocco, M.
登録日2003-07-09
公開日2003-10-21
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural characterization of the GSK-3beta active site using selective and non-selective ATP-mimetic inhibitors
J.Mol.Biol., 333, 2003
1Q4L
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BU of 1q4l by Molmil
GSK-3 Beta complexed with Inhibitor I-5
分子名称: 2-CHLORO-5-[4-(3-CHLORO-PHENYL)-2,5-DIOXO-2,5-DIHYDRO-1H-PYRROL-3-YLAMINO]-BENZOIC ACID, GLYCOGEN SYNTHASE KINASE-3 BETA
著者Bertrand, J.A, Thieffine, S, Vulpetti, A, Cristiani, C, Valsasina, B, Knapp, S, Kalisz, H.M, Flocco, M.
登録日2003-08-04
公開日2003-10-14
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.77 Å)
主引用文献Structural Characterization of the Gsk-3Beta Active Site Using Selective and Non-selective ATP-Mimetic Inhibitors
J.Mol.Biol., 333, 2003
1Q3W
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GSK-3 Beta complexed with Alsterpaullone
分子名称: 9-NITRO-5,12-DIHYDRO-7H-BENZO[2,3]AZEPINO[4,5-B]INDOL-6-ONE, GLYCOGEN SYNTHASE KINASE-3 BETA
著者Bertrand, J.A, Thieffine, S, Vulpetti, A, Cristiani, C, Valsasina, B, Knapp, S, Kalisz, H.M, Flocco, M.
登録日2003-08-01
公開日2003-10-21
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Characterization of the Gsk-3Beta Active Site Using Selective and Non-selective ATP-Mimetic Inhibitors
J.Mol.Biol., 333, 2003

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