PDB: 2624 件ウェブページステータス検索Chemie searchBIRD

---

6EQO	Tri-functional propionyl-CoA synthase of Erythrobacter sp. NAP1 with bound NADP+ and phosphomethylphosphonic acid adenylate ester 分子名称: Acetyl-coenzyme A synthetase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER 著者 Zarzycki, J, Bernhardsgruetter, I, Voegeli, B, Wagner, T, Engilberge, S, Girard, E, Shima, S, Erb, T.J. 登録日 2017-10-13 公開日 2018-10-24 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The multicatalytic compartment of propionyl-CoA synthase sequesters a toxic metabolite. Nat. Chem. Biol., 14, 2018
3A4I	Crystal structure of GMP synthetase PH1347 from Pyrococcus horikoshii OT3 分子名称: GMP synthase [glutamine-hydrolyzing] subunit B 著者 Maruoka, S, Horita, S, Lee, W.C, Nagata, K, Tanokura, M. 登録日 2009-07-07 公開日 2009-07-21 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Crystal structure of the ATPPase subunit and its substrate-dependent association with the GATase Subunit: a novel regulatory mechanism for a two-subunit-type GMP synthetase from Pyrococcus horikoshii OT3. J.Mol.Biol., 395, 2010
3PUP	Structure of Glycogen Synthase Kinase 3 beta (GSK3B) in complex with a ruthenium octasporine ligand (OS1) 分子名称: Glycogen synthase kinase-3 beta, Ruthenium octasporine 著者 Filippakopoulos, P, Kraling, K, Essen, L.O, Meggers, E, Knapp, S. 登録日 2010-12-06 公開日 2010-12-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.99 Å) 主引用文献 Structurally sophisticated octahedral metal complexes as highly selective protein kinase inhibitors. J.Am.Chem.Soc., 133, 2011
2C9H	Structure of mitochondrial beta-ketoacyl synthase 分子名称: MITOCHONDRIAL BETA-KETOACYL SYNTHASE, NICKEL (II) ION 著者 Bunkoczi, G, Wu, X, Smee, C, Gileadi, O, Arrowsmith, C, Edwards, A, Sundstrom, M, Weigelt, J, von Delft, F, Oppermann, U. 登録日 2005-12-12 公開日 2005-12-13 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of Mitochondrial Beta-Ketoacyl Synthase To be Published
8AUZ	Crystal structure of GSK3 beta (GSK3b) in complex with FL291. 分子名称: 8-morpholin-4-yl-2-pyridin-3-yl-[1,3]oxazolo[5,4-f]quinoxaline, Glycogen synthase kinase-3 beta, SULFATE ION 著者 Chaikuad, A, Mongin, F, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2022-08-26 公開日 2023-04-19 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.66 Å) 主引用文献 Oxazolo[5,4-f]quinoxaline-type selective inhibitors of glycogen synthase kinase-3 alpha (GSK-3 alpha ): Development and impact on temozolomide treatment of glioblastoma cells. Bioorg.Chem., 134, 2023
8AV1	Crystal structure of GSK3 beta (GSK3b) in complex with CD7. 分子名称: 1,2-ETHANEDIOL, 2-pyridin-3-yl-8-thiomorpholin-4-yl-[1,3]oxazolo[5,4-f]quinoxaline, Glycogen synthase kinase-3 beta, ... 著者 Chaikuad, A, Mongin, F, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2022-08-26 公開日 2023-04-19 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Oxazolo[5,4-f]quinoxaline-type selective inhibitors of glycogen synthase kinase-3 alpha (GSK-3 alpha ): Development and impact on temozolomide treatment of glioblastoma cells. Bioorg.Chem., 134, 2023
3SD0	Identification of a Glycogen Synthase Kinase-3b Inhibitor that Attenuates Hyperactivity in CLOCK Mutant Mice 分子名称: 3-(5-fluoro-6-iodo-1-methyl-1H-indol-3-yl)-4-(7-methoxy-1-benzofuran-3-yl)-1H-pyrrole-2,5-dione, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Glycogen synthase kinase-3 beta 著者 Mesecar, A.M, Walters, R.L. 登録日 2011-06-08 公開日 2011-08-03 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Identification of a Glycogen Synthase Kinase-3b Inhibitor that Attenuates Hyperactivity in CLOCK Mutant Mice To be Published
6AT1	STRUCTURAL CONSEQUENCES OF EFFECTOR BINDING TO THE T STATE OF ASPARTATE CARBAMOYLTRANSFERASE. CRYSTAL STRUCTURES OF THE UNLIGATED AND ATP-, AND CTP-COMPLEXED ENZYMES AT 2.6-ANGSTROMS RESOLUTION 分子名称: ASPARTATE CARBAMOYLTRANSFERASE (T STATE), CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ... 著者 Stevens, R.C, Gouaux, J.E, Lipscomb, W.N. 登録日 1990-04-26 公開日 1990-10-15 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural consequences of effector binding to the T state of aspartate carbamoyltransferase: crystal structures of the unligated and ATP- and CTP-complexed enzymes at 2.6-A resolution. Biochemistry, 29, 1990
3KZU	Crystal structure of 3-oxoacyl-(acyl carrier protein) synthase II from Brucella melitensis 分子名称: 1,2-ETHANEDIOL, 3-oxoacyl-(Acyl-carrier-protein) synthase ii, SULFATE ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2009-12-08 公開日 2009-12-15 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal structure of 3-oxoacyl-(acyl carrier protein) synthase II from Brucella melitensis TO BE PUBLISHED
1S1M	Crystal Structure of E. Coli CTP Synthetase 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CTP synthase, IODIDE ION, ... 著者 Endrizzi, J.A, Kim, H, Anderson, P.M, Baldwin, E.P. 登録日 2004-01-06 公開日 2004-06-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal Structure of Escherichia coli Cytidine Triphosphate Synthetase, a Nucleotide-Regulated Glutamine Amidotransferase/ATP-Dependent Amidoligase Fusion Protein and Homologue of Anticancer and Antiparasitic Drug Targets Biochemistry, 43, 2004
7FTX	Crystal Structure of apo human cyclic GMP-AMP synthase - hexagonal form 分子名称: Cyclic GMP-AMP synthase, SULFATE ION, ZINC ION 著者 Leibrock, L, Benz, J, Groebke-Zbinden, K, Rudolph, M.G. 登録日 2023-02-08 公開日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.831 Å) 主引用文献 Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
5JM8	The structure of ATP-bound aerobactin synthetase IucA from a hypervirulent pathotype of Klebsiella pneumoniae 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Aerobactin synthase IucA, MAGNESIUM ION 著者 Bailey, D.C, Drake, E.J, Gulick, A.M. 登録日 2016-04-28 公開日 2016-06-15 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural and Functional Characterization of Aerobactin Synthetase IucA from a Hypervirulent Pathotype of Klebsiella pneumoniae. Biochemistry, 55, 2016
5Z9A	Crystal structure of chorismate synthase from Pseudomonas aeruginosa 分子名称: Chorismate synthase 著者 Iqbal, N, Chaudhary, A, Kaur, P, Sharma, S, Singh, T.P. 登録日 2018-02-02 公開日 2018-02-28 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Crystal structure of chorismate synthase from Pseudomonas aeruginosa To Be Published
8I1O	Crystal structure of APSK2 domain from human PAPSS2 in complex with exogenous APS and ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-PHOSPHOSULFATE, Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 著者 Zhang, L, Song, W.Y, Zhang, L. 登録日 2023-01-13 公開日 2023-06-28 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Redox switching mechanism of the adenosine 5'-phosphosulfate kinase domain (APSK2) of human PAPS synthase 2. Structure, 31, 2023
8I1N	Crystal structure of APSK2 domain from human PAPSS2 in complex with endogenous APS and ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-PHOSPHOSULFATE, Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 著者 Zhang, L, Song, W.Y, Zhang, L. 登録日 2023-01-13 公開日 2023-06-28 最終更新日 2023-07-19 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Redox switching mechanism of the adenosine 5'-phosphosulfate kinase domain (APSK2) of human PAPS synthase 2. Structure, 31, 2023
4L7I	Crystal structure of S-Adenosylmethionine synthase from Sulfolobus solfataricus complexed with SAM and PPi 分子名称: DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... 著者 Wang, F, Hurley, K.A, Helmich, K.E, Singh, S, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) 登録日 2013-06-13 公開日 2013-07-03 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.189 Å) 主引用文献 Understanding molecular recognition of promiscuity of thermophilic methionine adenosyltransferase sMAT from Sulfolobus solfataricus. Febs J., 281, 2014
2PN1	Crystal structure of carbamoylphosphate synthase large subunit (split gene in MJ) (ZP_00538348.1) from Exiguobacterium sp. 255-15 at 2.00 A resolution 分子名称: Carbamoylphosphate synthase large subunit, GLYCEROL 著者 Joint Center for Structural Genomics (JCSG) 登録日 2007-04-23 公開日 2007-05-08 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of carbamoylphosphate synthase large subunit (split gene in MJ) (ZP_00538348.1) from Exiguobacterium sp. 255-15 at 2.00 A resolution To be published
7XA9	Structure of Arabidopsis thaliana CLCa 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Chloride channel protein CLC-a, MAGNESIUM ION, ... 著者 Ji, S, Jin, H, Kaiming, Z, Mingxing, W, Shanshan, L, Long, C. 登録日 2022-03-17 公開日 2023-03-22 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (2.84 Å) 主引用文献 Cryo-EM structure of the plant nitrate transporter AtCLCa reveals characteristics of the anion-binding site and the ATP-binding pocket. J.Biol.Chem., 299, 2023
4K9B	Structure of Ternary Complex of cGAS with dsDNA and Bound c[G(2 ,5 )pA(3 ,5 )p] 分子名称: ADENOSINE MONOPHOSPHATE, Cyclic GMP-AMP synthase, DNA-F, ... 著者 Gao, P, Wu, Y, Patel, D.J. 登録日 2013-04-19 公開日 2013-05-15 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase. Cell(Cambridge,Mass.), 153, 2013
8Y2H	GK tetramer of AtP5CS1 filament with adjacent hooks, reaction state 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Delta-1-pyrroline-5-carboxylate synthase A 著者 Zhang, T, Guo, C.J, Liu, J.L. 登録日 2024-01-26 公開日 2024-06-05 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Dynamic Arabidopsis P5CS filament facilitates substrate channelling. Nat.Plants, 10, 2024
6E5Y	1.50 Angstrom Resolution Crystal Structure of Argininosuccinate Synthase from Bordetella pertussis in Complex with AMP. 分子名称: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, Argininosuccinate synthase, ... 著者 Minasov, G, Shuvalova, L, Dubrovska, I, Cardona-Correa, A, Grimshaw, S, Kwon, K, Anderson, W.F, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2018-07-23 公開日 2018-08-01 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 1.50 Angstrom Resolution Crystal Structure of Argininosuccinate Synthase from Bordetella pertussis in Complex with AMP. To Be Published
4K9A	Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -pG(2 ,5 )pA 分子名称: ADENOSINE MONOPHOSPHATE, Cyclic GMP-AMP synthase, DNA-F, ... 著者 Gao, P, Wu, Y, Patel, D.J. 登録日 2013-04-19 公開日 2013-05-15 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.264 Å) 主引用文献 Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase. Cell(Cambridge,Mass.), 153, 2013
1CTS	CRYSTALLOGRAPHIC REFINEMENT AND ATOMIC MODELS OF TWO DIFFERENT FORMS OF CITRATE SYNTHASE AT 2.7 AND 1.7 ANGSTROMS RESOLUTION 分子名称: CITRATE SYNTHASE, CITRIC ACID 著者 Remington, S, Wiegand, G, Huber, R. 登録日 1984-01-27 公開日 1984-07-20 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystallographic refinement and atomic models of two different forms of citrate synthase at 2.7 and 1.7 A resolution. J.Mol.Biol., 158, 1982
7D4O	cyclic trinucleotide synthase CdnD in complex with ATP and ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cyclic AMP-AMP-GMP synthase, ... 著者 Yang, C.-S, Hou, M.-H, Tsai, C.-L, Wang, Y.-C, Ko, T.-P, Chen, Y. 登録日 2020-09-24 公開日 2021-03-17 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Crystal structure and functional implication of a bacterial cyclic AMP-AMP-GMP synthetase. Nucleic Acids Res., 49, 2021
4O90	Crystal structure of chorismate synthase from Acinetobacter baumannii at 2.6A resolution 分子名称: Chorismate synthase, GLYCEROL, L(+)-TARTARIC ACID 著者 Chaudhary, A, Singh, N, Shukla, P.K, Sinha, M, Bhushan, A, Kaur, P, Sharma, S, Singh, T.P. 登録日 2013-12-31 公開日 2014-01-22 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 Crystal structure of chorismate synthase from Acinetobacter baumannii at 2.6A resolution To be Published

<31323334353637383940414243444546>