6Z2H
Citryl-CoA lyase module of human ATP citrate lyase in complex with (3S)-citryl-CoA.
Summary for 6Z2H
| Entry DOI | 10.2210/pdb6z2h/pdb |
| Related | 6hxk 6hxl 6hxm |
| Descriptor | ATP-citrate synthase, (3S)-citryl-Coenzyme A, OXALOACETATE ION, ... (5 entities in total) |
| Functional Keywords | acetyl-coa production, metabolism, atp citrate lyase, lipogenesis, lyase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 4 |
| Total formula weight | 124738.30 |
| Authors | Verschueren, K.H.G.,Verstraete, K. (deposition date: 2020-05-15, release date: 2021-05-26, Last modification date: 2024-01-24) |
| Primary citation | Verstraete, K.,Verschueren, K.H.G.,Dansercoer, A.,Savvides, S.N. Acetyl-CoA is produced by the citrate synthase homology module of ATP-citrate lyase. Nat.Struct.Mol.Biol., 28:636-638, 2021 Cited by PubMed: 34294920DOI: 10.1038/s41594-021-00624-3 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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