6Z2H
Citryl-CoA lyase module of human ATP citrate lyase in complex with (3S)-citryl-CoA.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | ATP-citrate synthase | polymer | 270 | 30008.0 | 4 | UniProt (P53396) Pfam (PF00285) | Homo sapiens (Human) | ATP-citrate (pro-S-)-lyase,ACL,Citrate cleavage enzyme |
| 2 | E, H, K (A, C, D) | (3S)-citryl-Coenzyme A | non-polymer | 941.6 | 3 | Chemie (Q5B) PubChem (49859700) PubChem (3081994) PubChem (439266) PubChem (101471738) PubChem (11966144) PubChem (145712502) | |||
| 3 | F, I (A, C) | OXALOACETATE ION | non-polymer | 131.1 | 2 | Chemie (OAA) PubChem (3260017) | |||
| 4 | G, J (A, C) | ACETYL COENZYME *A | non-polymer | 809.6 | 2 | Chemie (ACO) PubChem (25210474) PubChem (24860528) PubChem (53393727) PubChem (56846401) PubChem (44141873) PubChem (45254004) PubChem (444493) PubChem (53245716) PubChem (87656764) PubChem (181) PubChem (6302) PubChem (87656765) PubChem (89102998) PubChem (91746285) PubChem (6857822) PubChem (6917106) PubChem (134956084) PubChem (10079099) PubChem (124511019) PubChem (11987898) PubChem (16061174) PubChem (124931617) PubChem (129274027) PubChem (154496096) PubChem (162968672) PubChem (170108977) | |||
| 5 | L, M, N, O (A, B, C, D) | water | water | 18.0 | 623 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 836 - 1101 (UniProt: P53396)
| PDB | External Database | Details |
|---|---|---|
| Gly 832 | - | expression tag |
| Ser 833 | - | expression tag |
| His 834 | - | expression tag |
| Met 835 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 120032.1 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 4706.2 | |
| All* | Total formula weight | 124738.3 |
