Crystal Structure of Thermus thermophilus HB8 Argininosuccinate Synthetase in complex with substrate

Summary for 1J1Z

Related1J20 1J21
DescriptorArgininosuccinate Synthetase, ADENOSINE-5'-TRIPHOSPHATE, CITRULLINE, ... (5 entities in total)
Functional Keywordsligase, atp-binding, riken structural genomics/proteomics initiative, rsgi, structural genomics
Biological sourceThermus thermophilus
Cellular locationCytoplasm (Probable) P59846
Total number of polymer chains4
Total molecular weight182765.85
Goto, M.,Hirotsu, K.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2002-12-24, release date: 2003-04-22, Last modification date: 2011-07-13)
Primary citation
Goto, M.,Omi, R.,Miyahara, I.,Sugahara, M.,Hirotsu, K.
Structures of argininosuccinate synthetase in enzyme-ATP-substrates and enzyme-AMP-product forms
J.Biol.Chem., 278:22964-22971, 2003
PubMed: 12684518 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M213198200
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.25115 0.3% 4.7% 2.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-12-02