7FUC

Crystal Structure of human cyclic GMP-AMP synthase in complex with 6-(2-chloro-4-methylphenyl)-2-(morpholin-4-ylmethyl)-1H-benzimidazole-4-carboxylic acid

Summary for 7FUC

• Entry DOI: 10.2210/pdb7fuc/pdb
• Group deposition: To be published (G_1002263)
• Descriptor: Cyclic GMP-AMP synthase, ZINC ION, (6M)-6-(2-chloro-4-methylphenyl)-2-[(morpholin-4-yl)methyl]-1H-benzimidazole-4-carboxylic acid (3 entities in total)
• Functional Keywords: immune response, transferase, ntase, dna sensor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 42856.16

Authors

Leibrock, L.,Benz, J.,Groebke-Zbinden, K.,Galley, G.,Rudolph, M.G. (deposition date: 2023-02-08, release date: 2024-02-21)

• Primary citation: Groebke-Zbinden, K.,Vandemeulebroucke, A.,Hilbert, M.,Rudolph, M.G.; Crystal Structure of a human cyclic GMP-AMP synthase complex; To be published,

Experimental method

X-RAY DIFFRACTION (2.52 Å)