2FF6
 
 | | Crystal structure of Gelsolin domain 1:ciboulot domain 2 hybrid in complex with actin | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Aguda, A.H, Xue, B, Robinson, R.C. | | 登録日 | 2005-12-19 | | 公開日 | 2006-03-21 | | 最終更新日 | 2018-05-23 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | The Structural Basis of Actin Interaction with Multiple WH2/beta-Thymosin Motif-Containing Proteins
Structure, 14, 2006
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4IT2
 | | Mn(III)-PPIX bound Tt H-NOX | | 分子名称: | MANGANESE PROTOPORPHYRIN IX, Methyl-accepting chemotaxis protein | | 著者 | Winter, M.B, Klemm, P.J, Phillips-Piro, C.M, Raymond, K.M, Marletta, M.A. | | 登録日 | 2013-01-17 | | 公開日 | 2013-02-27 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.097 Å) | | 主引用文献 | Porphyrin-Substituted H-NOX Proteins as High-Relaxivity MRI Contrast Agents.
Inorg.Chem., 52, 2013
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2QYI
 | | Crystal structure of a binary complex between an engineered trypsin inhibitor and Bovine trypsin | | 分子名称: | CALCIUM ION, Cationic trypsin, Chymotrypsin inhibitor 3, ... | | 著者 | Khamrui, S, Dasgupta, J, Dattagupta, J.K, Sen, U. | | 登録日 | 2007-08-15 | | 公開日 | 2008-08-19 | | 最終更新日 | 2021-11-10 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of a binary complex between an engineered trypsin inhibitor and Bovine trypsin
To be Published
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6SD6
 | | Structure of VapBC from Shigella sonnei | | 分子名称: | Antitoxin, tRNA(fMet)-specific endonuclease VapC | | 著者 | Lea, S.M, Hollingshead, S. | | 登録日 | 2019-07-26 | | 公開日 | 2020-08-26 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | | 主引用文献 | Polymorphisms in the VapBC toxin:antitoxin system mediate high frequency plasmid loss in Shigella sonnei
To Be Published
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6WL3
 | | preTCRbeta-pMHC complex crystal structure | | 分子名称: | ARG-GLY-TYR-LEU-TYR-GLN-GLY-LEU, H-2 class I histocompatibility antigen, K-B alpha chain, ... | | 著者 | Li, X, Mallis, R.J, Mizsei, R, Tan, K, Reinherz, E.L, Wang, J. | | 登録日 | 2020-04-18 | | 公開日 | 2020-12-23 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.45 Å) | | 主引用文献 | Pre-T cell receptors topologically sample self-ligands during thymocyte beta-selection.
Science, 371, 2021
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6WL2
 | | preTCRbeta-pMHC complex crystal structure | | 分子名称: | ARG-GLY-TYR-VAL-TYR-GLN-GLY-LEU, H-2 class I histocompatibility antigen, K-B alpha chain, ... | | 著者 | Li, X, Mallis, R.J, Mizsei, R, Tan, K, Reinherz, E.L, Wang, J. | | 登録日 | 2020-04-18 | | 公開日 | 2020-12-23 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Pre-T cell receptors topologically sample self-ligands during thymocyte beta-selection.
Science, 371, 2021
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6WL4
 | | preTCRbeta-pMHC complex crystal structure | | 分子名称: | ARG-GLY-TYR-VAL-TYR-GLN-GLY-LEU, H-2 class I histocompatibility antigen, K-B alpha chain, ... | | 著者 | Li, X, Mallis, R.J, Mizsei, R, Tan, K, Reinherz, E.L, Wang, J. | | 登録日 | 2020-04-18 | | 公開日 | 2020-12-23 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Pre-T cell receptors topologically sample self-ligands during thymocyte beta-selection.
Science, 371, 2021
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4AW9
 | | Crystal structure of active legumain in complex with YVAD-CMK | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACE-TYR-VAL-ALA-ASP-CHLOROMETHYLKETONE, LEGUMAIN, ... | | 著者 | Dall, E, Brandstetter, H. | | 登録日 | 2012-06-01 | | 公開日 | 2013-06-26 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Mechanistic and Structural Studies on Legumain Explain its Zymogenicity, Distinct Activation Pathways, and Regulation
Proc.Natl.Acad.Sci.USA, 110, 2013
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4AWA
 | | Crystal structure of active legumain in complex with YVAD-CMK at pH 5.0 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, LEGUMAIN, SULFATE ION, ... | | 著者 | Dall, E, Brandstetter, H. | | 登録日 | 2012-06-01 | | 公開日 | 2013-06-26 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Mechanistic and Structural Studies on Legumain Explain its Zymogenicity, Distinct Activation Pathways, and Regulation
Proc.Natl.Acad.Sci.USA, 110, 2013
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4AWB
 | | Crystal structure of active legumain in complex with AAN-CMK | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, LEGUMAIN, MERCURY (II) ION, ... | | 著者 | Dall, E, Brandstetter, H. | | 登録日 | 2012-06-01 | | 公開日 | 2013-06-26 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Mechanistic and Structural Studies on Legumain Explain its Zymogenicity, Distinct Activation Pathways, and Regulation
Proc.Natl.Acad.Sci.USA, 110, 2013
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6XAG
 | | Apo BRAF dimer bound to 14-3-3 | | 分子名称: | 1,2-ETHANEDIOL, 14-3-3 protein zeta/delta, Serine/threonine-protein kinase B-raf | | 著者 | Liau, N.P.D, Hymowitz, S.G, Sudhamsu, J. | | 登録日 | 2020-06-04 | | 公開日 | 2020-10-07 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Dimerization Induced by C-Terminal 14-3-3 Binding Is Sufficient for BRAF Kinase Activation.
Biochemistry, 59, 2020
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3U89
 | | Crystal structure of one turn of g/c rich b-dna revisited | | 分子名称: | 5'-D(*CP*CP*AP*GP*GP*CP*CP*TP*GP*G) -3', MAGNESIUM ION | | 著者 | Maehigashi, T, Woods, K.K, Moulaei, T, Komeda, S, Williams, L.D. | | 登録日 | 2011-10-16 | | 公開日 | 2011-11-09 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (0.96 Å) | | 主引用文献 | B-DNA structure is intrinsically polymorphic: even at the level of base pair positions.
Nucleic Acids Res., 40, 2012
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2B2K
 | | structure of Y104F IDI-1 mutant in complex with EIPP | | 分子名称: | 4-HYDROXY-3-METHYL BUTYL DIPHOSPHATE, Isopentenyl-diphosphate delta-isomerase, MAGNESIUM ION, ... | | 著者 | Wouters, J. | | 登録日 | 2005-09-19 | | 公開日 | 2006-09-05 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Structural role for Tyr-104 in Escherichia coli isopentenyl-diphosphate isomerase: site-directed mutagenesis, enzymology, and protein crystallography
J.Biol.Chem., 281, 2006
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1ICT
 | | MONOCLINIC FORM OF HUMAN TRANSTHYRETIN COMPLEXED WITH THYROXINE (T4) | | 分子名称: | 3,5,3',5'-TETRAIODO-L-THYRONINE, TRANSTHYRETIN | | 著者 | Wojtczak, A, Neumann, P, Cody, V. | | 登録日 | 2001-04-02 | | 公開日 | 2002-04-03 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structure of a new polymorphic monoclinic form of human transthyretin at 3 A resolution reveals a mixed complex between unliganded and T4-bound tetramers of TTR.
Acta Crystallogr.,Sect.D, 57, 2001
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1LCN
 | | Monoclinic hen egg white lysozyme, thiocyanate complex | | 分子名称: | PROTEIN (LYSOZYME), THIOCYANATE ION | | 著者 | Hamiaux, C, Prange, T, Ducruix, A, Vaney, M.C. | | 登録日 | 1998-10-27 | | 公開日 | 1998-11-04 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Structural effects of monovalent anions on polymorphic lysozyme crystals.
Acta Crystallogr.,Sect.D, 57, 2001
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1IGB
 | | AEROMONAS PROTEOLYTICA AMINOPEPTIDASE COMPLEXED WITH THE INHIBITOR PARA-IODO-D-PHENYLALANINE HYDROXAMATE | | 分子名称: | AMINOPEPTIDASE, PARA-IODO-D-PHENYLALANINE HYDROXAMIC ACID, ZINC ION | | 著者 | Chevrier, B, D'Orchymont, H, Schalk, C, Tarnus, C, Moras, D. | | 登録日 | 1996-02-27 | | 公開日 | 1996-08-01 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The structure of the Aeromonas proteolytica aminopeptidase complexed with a hydroxamate inhibitor. Involvement in catalysis of Glu151 and two zinc ions of the co-catalytic unit.
Eur.J.Biochem., 237, 1996
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2R5P
 | | Crystal Structure Analysis of HIV-1 Subtype C Protease Complexed with Indinavir | | 分子名称: | CHLORIDE ION, N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE, Protease, ... | | 著者 | Coman, R.M, Robbins, A.H, McKenna, R, Dunn, B.M. | | 登録日 | 2007-09-04 | | 公開日 | 2007-11-20 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The Contribution of Naturally Occurring Polymorphisms in Altering the Biochemical and Structural Characteristics of HIV-1 Subtype C Protease
Biochemistry, 47, 2008
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2RHJ
 | | Synthetic Gene Encoded Bacillus Subtilis FtsZ with Two Sulfate Ions and Sodium Ion in the Nucleotide Pocket | | 分子名称: | ACETATE ION, Cell Division Protein ftsZ, SODIUM ION, ... | | 著者 | Lovell, S, Halloran, Z, Hjerrild, K, Sheridan, D, Burgin, A, Stewart, L, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D) | | 登録日 | 2007-10-09 | | 公開日 | 2008-10-21 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.761 Å) | | 主引用文献 | Combined protein construct and synthetic gene engineering for heterologous protein expression and crystallization using Gene Composer.
BMC Biotechnol., 9, 2009
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7ZLJ
 | | Cryo-EM structure of C-mannosyltransferase CeDPY19, in ternary complex with Dol25-P-C-Man and acceptor peptide, bound to CMT2-Fab and anti-Fab nanobody | | 分子名称: | Anti-Fab nanobody, C-mannosyltransferase dpy-19, CMT2-Fab heavy chain, ... | | 著者 | Bloch, J.S, Mao, R, Mukherjee, S, Boilevin, J, Irobalieva, R, Darbre, T, Reymond, J.L, Kossiakoff, A.A, Goddard-Borger, E.D, Locher, K.P. | | 登録日 | 2022-04-15 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-05-10 | | 実験手法 | ELECTRON MICROSCOPY (3.63 Å) | | 主引用文献 | Structure, sequon recognition and mechanism of tryptophan C-mannosyltransferase.
Nat.Chem.Biol., 19, 2023
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7ZLI
 | | Cryo-EM structure of C-mannosyltransferase CeDPY19, in complex with Dol25-P-Man and bound to CMT2-Fab and anti-Fab nanobody | | 分子名称: | Anti-Fab nanobody, C-mannosyltransferase dpy-19, CMT2-Fab heavy chain, ... | | 著者 | Bloch, J.S, Mukherjee, S, Boilevin, J, Irobalieva, R, Darbre, T, Reymond, J.L, Kossiakoff, A.A, Goddard-Borger, E.D, Locher, K.P. | | 登録日 | 2022-04-15 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-05-10 | | 実験手法 | ELECTRON MICROSCOPY (2.99 Å) | | 主引用文献 | Structure, sequon recognition and mechanism of tryptophan C-mannosyltransferase.
Nat.Chem.Biol., 19, 2023
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2RHO
 | | Synthetic Gene Encoded Bacillus Subtilis FtsZ NCS Dimer with Bound GDP and GTP-gamma-S | | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Cell Division Protein ftsZ, GUANOSINE-5'-DIPHOSPHATE | | 著者 | Lovell, S, Halloran, Z, Hjerrild, K, Sheridan, D, Burgin, A, Stewart, L, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D) | | 登録日 | 2007-10-09 | | 公開日 | 2008-10-21 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Combined protein construct and synthetic gene engineering for heterologous protein expression and crystallization using Gene Composer.
BMC Biotechnol., 9, 2009
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4MNE
 | | Crystal structure of the BRAF:MEK1 complex | | 分子名称: | 7-fluoro-3-[(2-fluoro-4-iodophenyl)amino]-N-{[(2S)-2-hydroxypropyl]oxy}furo[3,2-c]pyridine-2-carboxamide, CHLORIDE ION, Dual specificity mitogen-activated protein kinase kinase 1, ... | | 著者 | Sudhamsu, J, Haling, J.R, Morales, T, Brandhuber, B, Hymowitz, S.G. | | 登録日 | 2013-09-10 | | 公開日 | 2014-06-18 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.8483 Å) | | 主引用文献 | Structure of the BRAF-MEK Complex Reveals a Kinase Activity Independent Role for BRAF in MAPK Signaling.
Cancer Cell, 26, 2014
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3T6P
 | | IAP antagonist-induced conformational change in cIAP1 promotes E3 ligase activation via dimerization | | 分子名称: | Baculoviral IAP repeat-containing protein 2, ZINC ION | | 著者 | Dueber, E.C, Schoeffler, A.J, Lingel, A, Elliott, M, Fedorova, A.V, Giannetti, A.M, Zobel, K, Maurer, B, Varfolomeev, E, Wu, P, Wallweber, H, Hymowitz, S, Deshayes, K, Vucic, D, Fairbrother, W.J. | | 登録日 | 2011-07-28 | | 公開日 | 2011-11-02 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.897 Å) | | 主引用文献 | Antagonists induce a conformational change in cIAP1 that promotes autoubiquitination.
Science, 334, 2011
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2RHH
 | | Synthetic Gene Encoded Bacillus Subtilis FtsZ with Bound Sulfate Ion | | 分子名称: | Cell Division Protein ftsZ, SULFATE ION | | 著者 | Lovell, S, Halloran, Z, Hjerrild, K, Sheridan, D, Burgin, A, Stewart, L, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D) | | 登録日 | 2007-10-09 | | 公開日 | 2008-10-21 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | | 主引用文献 | Combined protein construct and synthetic gene engineering for heterologous protein expression and crystallization using Gene Composer.
BMC Biotechnol., 9, 2009
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2RHL
 | | Synthetic Gene Encoded Bacillus Subtilis FtsZ NCS Dimer with Bound GDP | | 分子名称: | Cell Division Protein ftsZ, GUANOSINE-5'-DIPHOSPHATE | | 著者 | Lovell, S, Halloran, Z, Hjerrild, K, Sheridan, D, Burgin, A, Stewart, L, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D) | | 登録日 | 2007-10-09 | | 公開日 | 2008-10-21 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Combined protein construct and synthetic gene engineering for heterologous protein expression and crystallization using Gene Composer.
BMC Biotechnol., 9, 2009
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