1ICT

MONOCLINIC FORM OF HUMAN TRANSTHYRETIN COMPLEXED WITH THYROXINE (T4)

Summary for 1ICT

Entry DOI	10.2210/pdb1ict/pdb
Related	1TTA 2PAB 2ROX
Descriptor	TRANSTHYRETIN, 3,5,3',5'-TETRAIODO-L-THYRONINE (2 entities in total)
Functional Keywords	albumin, transport, amyloid, thyroid hormone, liver, plasma, polyneuropathy, thyroxine, prealbumin, greek key beta barrel, transport protein
Biological source	Homo sapiens (human)
Cellular location	Secreted: P02766
Total number of polymer chains	8
Total formula weight	111772.62
Authors	Wojtczak, A.,Neumann, P.,Cody, V. (deposition date: 2001-04-02, release date: 2002-04-03, Last modification date: 2023-11-15)
Primary citation	Wojtczak, A.,Neumann, P.,Cody, V. Structure of a new polymorphic monoclinic form of human transthyretin at 3 A resolution reveals a mixed complex between unliganded and T4-bound tetramers of TTR. Acta Crystallogr.,Sect.D, 57:957-967, 2001 Cited by PubMed: 11418763 DOI: 10.1107/S0907444901006047 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation