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2IPU
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PFA1 Fab fragment complexed with Abeta 1-8 peptide
分子名称: ACETAMIDE, GLYCEROL, IgG2a Fab fragment Heavy Chain, ...
著者Gardberg, A.S, Dealwis, C.
登録日2006-10-12
公開日2007-10-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Molecular basis for passive immunotherapy of Alzheimer's disease
Proc.Natl.Acad.Sci.Usa, 104, 2007
3AGV
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BU of 3agv by Molmil
Crystal structure of a human IgG-aptamer complex
分子名称: 5'-R(*GP*GP*AP*GP*GP*(UFT)P*GP*(CFZ)P*(UFT)P*(CFZ)P*(CFZ)P*GP*AP*AP*A*GP*GP*AP*AP*(CFZ)P*(UFT)P*(CFZ)P*(CFZ)P*A)-3', CALCIUM ION, Ig gamma-1 chain C region, ...
著者Nomura, Y, Sugiyama, S, Sakamoto, T, Miyakawa, S, Adachi, H, Takano, K, Murakami, S, Inoue, T, Mori, Y, Nakamura, Y, Matsumura, H.
登録日2010-04-08
公開日2010-11-10
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Conformational plasticity of RNA for target recognition as revealed by the 2.15 A crystal structure of a human IgG-aptamer complex
Nucleic Acids Res., 38, 2010
1Y12
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BU of 1y12 by Molmil
Structure of a hemolysin-coregulated protein from Pseudomonas aeruginosa
分子名称: hypothetical protein PA0085
著者Cuff, M.E, Zhou, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2004-11-16
公開日2005-01-25
最終更新日2020-03-11
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献A virulence locus of Pseudomonas aeruginosa encodes a protein secretion apparatus.
Science, 312, 2006
2JDF
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BU of 2jdf by Molmil
Human gamma-B crystallin
分子名称: GAMMA CRYSTALLIN B
著者Ebersbach, H, Fiedler, E, Scheuermann, T, Fiedler, M, Stubbs, M.T, Reimann, C, Proetzel, G, Rudolph, R, Fiedler, U.
登録日2007-01-08
公開日2007-07-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Affilin-Novel Binding Molecules Based on Human Gamma-B-Crystallin, an All Beta-Sheet Protein.
J.Mol.Biol., 372, 2007
2ME4
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BU of 2me4 by Molmil
HIV-1 gp41 clade C Membrane Proximal External Region peptide in DPC micelle
分子名称: Envelope glycoprotein gp160
著者Sun, Z.J, Wagner, G, Reinherz, E.L, Kim, M, Song, L, Choi, J, Cheng, Y, Chowdhury, B, Bellot, G, Shih, W.
登録日2013-09-20
公開日2013-10-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41.
J.Mol.Biol., 426, 2014
2ME1
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BU of 2me1 by Molmil
HIV-1 gp41 clade B double alanine mutant Membrane Proximal External Region peptide in DPC micelle
分子名称: Gp41
著者Sun, Z.J, Wagner, G, Reinherz, E.L, Kim, M, Song, L, Choi, J, Cheng, Y, Chowdhury, B, Bellot, G, Shih, W.
登録日2013-09-20
公開日2013-10-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41.
J.Mol.Biol., 426, 2014
2JO7
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BU of 2jo7 by Molmil
Solution structure of the adhesion protein Bd37 from Babesia divergens
分子名称: Glycosylphosphatidylinositol-anchored merozoite surface protein
著者Auguin, D, Yang, Y, Lohr, F, Arold, S, Schetters, T, Precigout, E, Gorenflot, A, Delbecq, S, Roumestand, C.
登録日2007-02-26
公開日2007-12-11
最終更新日2023-12-20
実験手法SOLUTION NMR
主引用文献The Solution Structure of the Adhesion Protein Bd37 from Babesia divergens Reveals Structural Homology with Eukaryotic Proteins Involved in Membrane Trafficking
J.Mol.Biol., 375, 2007
5KMM
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BU of 5kmm by Molmil
TrkA JM-kinase with 1-(2-methyl-4-phenyl-pyrimidin-5-yl)-3-(1-naphthyl)urea
分子名称: 1-(2-methyl-4-phenyl-pyrimidin-5-yl)-3-naphthalen-1-yl-urea, High affinity nerve growth factor receptor
著者Su, H.P.
登録日2016-06-27
公開日2016-12-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Structural characterization of nonactive site, TrkA-selective kinase inhibitors.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5L8L
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BU of 5l8l by Molmil
Aurora-A kinase domain in complex with vNAR-D01 (crystal form 1)
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, Aurora kinase A, ...
著者Burgess, S.G, Bayliss, R.
登録日2016-06-08
公開日2016-07-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Allosteric inhibition of Aurora-A kinase by a synthetic vNAR domain.
Open Biology, 6, 2016
6EAQ
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BU of 6eaq by Molmil
Glycosylated FCGR3B / CD16b in complex with afucosylated IgG1 Fc
分子名称: Immunoglobulin gamma-1 heavy chain, Low affinity immunoglobulin gamma Fc region receptor III-B, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Roberts, J.T, Barb, A.W.
登録日2018-08-03
公開日2018-11-07
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献A single amino acid distorts the Fc gamma receptor IIIb/CD16b structure upon binding immunoglobulin G1 and reduces affinity relative to CD16a.
J. Biol. Chem., 293, 2018
5KMJ
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BU of 5kmj by Molmil
TrkA JM-kinase with {N}-(2-pyridylmethyl)-2-[2-(2-thienyl)indol-1-yl]acetamide
分子名称: High affinity nerve growth factor receptor, ~{N}-(pyridin-2-ylmethyl)-2-(2-thiophen-2-ylindol-1-yl)ethanamide
著者Su, H.P.
登録日2016-06-27
公開日2016-12-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Structural characterization of nonactive site, TrkA-selective kinase inhibitors.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6ZWJ
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BU of 6zwj by Molmil
Neisseria gonorrhoeae transaldolase at 1.35 Angstrom resolution
分子名称: CITRIC ACID, GLYCEROL, Transaldolase
著者Rabe von Pappenheim, F, Wensien, M, Sautner, V, Tittmann, K.
登録日2020-07-28
公開日2021-03-24
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献A lysine-cysteine redox switch with an NOS bridge regulates enzyme function.
Nature, 593, 2021
6ZWF
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BU of 6zwf by Molmil
Neisseria gonorrhoeae transaldolase
分子名称: 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, CITRIC ACID, ...
著者Rabe von Pappenheim, F, Wensien, M, Funk, L.-M, Sautner, V, Tittmann, K.
登録日2020-07-28
公開日2021-03-24
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献A lysine-cysteine redox switch with an NOS bridge regulates enzyme function.
Nature, 593, 2021
6ZWH
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BU of 6zwh by Molmil
Neisseria gonorrhoeae transaldolase at 1.5 Angstrom resolution
分子名称: 1,2-ETHANEDIOL, ACETATE ION, GLYCEROL, ...
著者Rabe von Pappenheim, F, Wensien, M, Funk, L.-M, Sautner, V, Tittmann, K.
登録日2020-07-28
公開日2021-03-24
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献A lysine-cysteine redox switch with an NOS bridge regulates enzyme function.
Nature, 593, 2021
6ZX4
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BU of 6zx4 by Molmil
Neisseria gonorrhoeae transaldolase
分子名称: CITRIC ACID, GLYCEROL, Transaldolase
著者Sautner, V, Rabe von Pappenheim, F, Wensien, M, Tittmann, K.
登録日2020-07-29
公開日2021-03-24
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (0.96 Å)
主引用文献A lysine-cysteine redox switch with an NOS bridge regulates enzyme function.
Nature, 593, 2021
7P3I
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BU of 7p3i by Molmil
Crystal structure of human CD40/TNFRSF5 in complex with the anti-CD40 DARPin protein
分子名称: Darpin, SODIUM ION, Tumor necrosis factor receptor superfamily member 5
著者Malvezzi, F, Mangold, S, Hospodarsch, T, Reichen, C, Iss, C, Lammens, A, Krapp, S, Domke, C.
登録日2021-07-07
公開日2022-04-06
最終更新日2022-05-11
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献A Multispecific Anti-CD40 DARPin Construct Induces Tumor-Selective CD40 Activation and Tumor Regression.
Cancer Immunol Res, 10, 2022
5L2H
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BU of 5l2h by Molmil
Crystal Structure of W26A mutant of anti-EGFR Centyrin P54AR4-83v2
分子名称: Centyrin, GLYCEROL
著者Cardoso, R.M.F, Goldberg, S.D, O Neil, K.T, Gilliland, G.L.
登録日2016-08-01
公開日2016-11-02
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.8013 Å)
主引用文献Engineering a targeted delivery platform using Centyrins.
Protein Eng. Des. Sel., 29, 2016
5KWB
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BU of 5kwb by Molmil
Crystal Structure of the Receptor Binding Domain of the Spike Glycoprotein of Human Betacoronavirus HKU1 (HKU1 1A-CTD, 1.9 angstrom, molecular replacement)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, Spike glycoprotein, ...
著者Guan, H, Wojdyla, J.A, Wang, M, Cui, S.
登録日2016-07-17
公開日2017-06-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Crystal structure of the receptor binding domain of the spike glycoprotein of human betacoronavirus HKU1
Nat Commun, 8, 2017
3D8L
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BU of 3d8l by Molmil
Crystal structure of ORF12 from the lactococcus lactis bacteriophage p2
分子名称: ORF12
著者Siponen, M.I, Spinelli, S, Lichiere, J, Moineau, S, Cambillau, C, Campanacci, V.
登録日2008-05-23
公開日2009-04-14
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of ORF12 from Lactococcus lactis phage p2 identifies a tape measure protein chaperone
J.Bacteriol., 191, 2009
6ZW0
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BU of 6zw0 by Molmil
Connectase MJ0548 from Methanocaldococcus jannaschii in complex with an MtrA-derived peptide
分子名称: 2-[3,6-bis(oxidanyl)-9~{H}-xanthen-9-yl]-5-[(6-oxidanyl-6-oxidanylidene-hexyl)carbamothioylamino]benzoic acid, Connectase MJ0548, Tetrahydromethanopterin S-methyltransferase subunit A
著者Fuchs, A.C.D, Hartmann, M.D.
登録日2020-07-27
公開日2021-06-09
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Archaeal Connectase is a specific and efficient protein ligase related to proteasome beta subunits.
Proc.Natl.Acad.Sci.USA, 118, 2021
6ZVZ
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BU of 6zvz by Molmil
Connectase MJ0548 from Methanocaldococcus jannaschii
分子名称: Connectase MJ0548
著者Ammelburg, M, Hartmann, M.D.
登録日2020-07-27
公開日2021-06-09
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Archaeal Connectase is a specific and efficient protein ligase related to proteasome beta subunits.
Proc.Natl.Acad.Sci.USA, 118, 2021
5L8K
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BU of 5l8k by Molmil
Aurora-A kinase domain in complex with vNAR-D01 (crystal form 2)
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, Aurora kinase A, ...
著者Burgess, S.G, Bayliss, R.
登録日2016-06-08
公開日2016-07-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Allosteric inhibition of Aurora-A kinase by a synthetic vNAR domain.
Open Biology, 6, 2016
4C57
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BU of 4c57 by Molmil
Structure of GAK kinase in complex with a nanobody
分子名称: (2Z,3E)-2,3'-BIINDOLE-2',3(1H,1'H)-DIONE 3-{O-[(3R)-3,4-DIHYDROXYBUTYL]OXIME}, 1,2-ETHANEDIOL, Cyclin-G-associated kinase, ...
著者Chaikuad, A, Keates, T, Krojer, T, Allerston, C.K, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Muller-Knapp, S.
登録日2013-09-10
公開日2013-10-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structure of Cyclin G-Associated Kinase (Gak) Trapped in Different Conformations Using Nanobodies.
Biochem.J., 459, 2014
4C58
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Structure of GAK kinase in complex with nanobody (NbGAK_4)
分子名称: 1,2-ETHANEDIOL, 9-HYDROXY-4-PHENYLPYRROLO[3,4-C]CARBAZOLE-1,3(2H,6H)-DIONE, Cyclin-G-associated kinase, ...
著者Chaikuad, A, Keates, T, Allerston, C.K, Gileadi, O, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Muller-Knapp, S.
登録日2013-09-10
公開日2013-10-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Structure of cyclin G-associated kinase (GAK) trapped in different conformations using nanobodies.
Biochem. J., 459, 2014
2R0Z
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BU of 2r0z by Molmil
PFA1 FAB complexed with GripI peptide fragment
分子名称: GLYCEROL, GripI peptide fragment, IgG2a Fab fragment heavy chain, ...
著者Gardberg, A.S, Dealwis, C.
登録日2007-08-21
公開日2007-10-16
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.096 Å)
主引用文献Molecular basis for passive immunotherapy of Alzheimer's disease
Proc.Natl.Acad.Sci.Usa, 104, 2007

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