PDB: 95574 件ウェブページステータス検索Chemie searchBIRD

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5EBH	Crystal Structure HEW Lysozyme processed with the CrystalDirect automated mounting and cryo-cooling technology 分子名称: Lysozyme C 著者 Zander, U, Hoffmann, G, Cornaciu, I, Marquez, J.A. 登録日 2015-10-19 公開日 2016-04-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Automated harvesting and processing of protein crystals through laser photoablation. Acta Crystallogr D Struct Biol, 72, 2016
6UXW	SWI/SNF nucleosome complex with ADP-BeFx 分子名称: 601 sequence bottom strand, 601 sequence top strand, ADENOSINE-5'-DIPHOSPHATE, ... 著者 He, Y, Han, Y. 登録日 2019-11-08 公開日 2020-03-18 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (8.96 Å) 主引用文献 Cryo-EM structure of SWI/SNF complex bound to a nucleosome. Nature, 579, 2020
4RSK	STRUCTURE OF THE K7A/R10A/K66A VARIANT OF RIBONUCLEASE A COMPLEXED WITH 3'-UMP 分子名称: 3'-URIDINEMONOPHOSPHATE, RIBONUCLEASE A 著者 Schultz, L.W, Fisher, B.M, Raines, R.T. 登録日 1998-04-09 公開日 1998-12-09 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Coulombic Effects of Remote Subsites on the Active Site of Ribonuclease A Biochemistry, 37, 1998
8CB1	Crystal structure of human lysosomal acid-alpha-glucosidase, GAA, in complex with N-PNT-DNM 15 分子名称: (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-(phenanthren-9-ylmethoxy)pentyl]piperidine-3,4,5-triol, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Sulzenbacher, G, Roig-Zamboni, V, Overkleeft, H, Artola, M. 登録日 2023-01-25 公開日 2023-09-13 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Fluorescence polarisation activity-based protein profiling for the identification of deoxynojirimycin-type inhibitors selective for lysosomal retaining alpha- and beta-glucosidases. Chem Sci, 14, 2023
8CB6	Crystal structure of human lysosomal acid-alpha-glucosidase, GAA, in covalent complex with TAMRA tagged 1,6-Epi-cylcophellitol aziridine activity based probe 分子名称: (1S,2R,3R,4R,5R)-5-[8-[4-(4-azanylbutyl)-1,2,3-triazol-1-yl]octylamino]-4-(hydroxymethyl)cyclohexane-1,2,3-triol, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Sulzenbacher, G, Roig-Zamboni, V, Overkleeft, H, Artola, M. 登録日 2023-01-25 公開日 2023-09-13 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Fluorescence polarisation activity-based protein profiling for the identification of deoxynojirimycin-type inhibitors selective for lysosomal retaining alpha- and beta-glucosidases. Chem Sci, 14, 2023
4S0G	Crystal structure of PTPN3 (PTPH1) in complex with Eps15 pTyr849 P850V peptide 分子名称: Peptide from Epidermal growth factor receptor substrate 15, Tyrosine-protein phosphatase non-receptor type 3 著者 Chen, K.-E, Meng, T.C, Wang, A.H.-J. 登録日 2014-12-31 公開日 2015-03-11 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.723 Å) 主引用文献 Substrate specificity and plasticity of FERM-containing protein tyrosine phosphatases. Structure, 23, 2015
5FXK	GluN1b-GluN2B NMDA receptor structure-Class Y 分子名称: N-METHYL-D-ASPARTATE RECEPTOR GLUN1, N-METHYL-D-ASPARTATE RECEPTOR GLUN2B 著者 Tajima, N, Karakas, E, Grant, T, Simorowski, N, Diaz-Avalos, R, Grigorieff, N, Furukawa, H. 登録日 2016-03-02 公開日 2016-05-11 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (6.4 Å) 主引用文献 Activation of Nmda Receptors and the Mechanism of Inhibition by Ifenprodil. Nature, 534, 2016
1GHL	THE THREE-DIMENSIONAL STRUCTURE OF PHEASANT AND GUINEA-FOWL EGG LYSOZYMES 分子名称: PHEASANT EGG WHITE LYSOZYME 著者 Alzari, P.M, Lescar, J. 登録日 1993-05-04 公開日 1993-10-31 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structures of pheasant and guinea fowl egg-white lysozymes Protein Sci., 3, 1994
4TNU	Human brain aspartoacylase mutant Y231C complex with intermediate analog (N-phosphonomethyl-L-aspartate) 分子名称: Aspartoacylase, N-[HYDROXY(METHYL)PHOSPHORYL]-L-ASPARTIC ACID, ZINC ION 著者 Wijayasinghe, Y.S, Pavlovsky, A.G, Viola, R.E. 登録日 2014-06-05 公開日 2014-07-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Aspartoacylase catalytic deficiency as the cause of canavan disease: a structural perspective. Biochemistry, 53, 2014
4RNT	HIS 92 ALA MUTATION IN RIBONUCLEASE T1 INDUCES SEGMENTAL FLEXIBILITY. AN X-RAY STUDY 分子名称: RIBONUCLEASE T1 著者 Saenger, W, Koellner, G. 登録日 1990-02-13 公開日 1992-01-15 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 His92Ala mutation in ribonuclease T1 induces segmental flexibility. An X-ray study. J.Mol.Biol., 224, 1992
5FXG	GLUN1B-GLUN2B NMDA RECEPTOR IN ACTIVE CONFORMATION 分子名称: N-METHYL-D-ASPARTATE RECEPTOR GLUN1, N-METHYL-D-ASPARTATE RECEPTOR GLUN2B 著者 Tajima, N, Karakas, E, Grant, T, Simorowski, N, Diaz-Avalos, R, Grigorieff, N, Furukawa, H. 登録日 2016-03-02 公開日 2016-05-11 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (6.8 Å) 主引用文献 Activation of Nmda Receptors and the Mechanism of Inhibition by Ifenprodil. Nature, 534, 2016
5B0Z	The crystal structure of the nucleosome containing H3.2, at 1.98 A resolution 分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ... 著者 Suzuki, Y, Horikoshi, N, Kato, D, Kurumizaka, H. 登録日 2015-11-14 公開日 2016-01-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.987 Å) 主引用文献 Crystal structure of the nucleosome containing histone H3 with crotonylated lysine 122 Biochem.Biophys.Res.Commun., 469, 2016
5HK5	Structure of the Grem2-GDF5 Inhibitory Complex 分子名称: Gremlin-2, Growth/differentiation factor 5 著者 Nolan, K, Thompson, T.B, Read, R.J. 登録日 2016-01-13 公開日 2016-08-24 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure of Gremlin-2 in Complex with GDF5 Gives Insight into DAN-Family-Mediated BMP Antagonism. Cell Rep, 16, 2016
8C84	Crystal structure of MADS-box/MEF2D N-terminal domain complex 分子名称: DNA (5'-D(P*AP*AP*CP*TP*AP*TP*TP*TP*AP*TP*AP*AP*GP*A)-3'), DNA (5'-D(P*TP*CP*TP*TP*AP*TP*AP*AP*AP*TP*AP*GP*TP*T)-3'), MEF2D protein 著者 Chinellato, M, Carli, A, Perin, S, Mazzoccato, Y, Di Giorgio, E, Brancolini, C, Angelini, A, Cendron, L. 登録日 2023-01-18 公開日 2024-01-31 最終更新日 2024-04-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Folding of Class IIa HDAC Derived Peptides into alpha-helices Upon Binding to Myocyte Enhancer Factor-2 in Complex with DNA. J.Mol.Biol., 436, 2024
6UXV	SWI/SNF Body Module 分子名称: SWI/SNF chromatin-remodeling complex subunit SNF5, SWI/SNF chromatin-remodeling complex subunit SWI1, SWI/SNF complex subunit SWI3, ... 著者 He, Y, Han, Y. 登録日 2019-11-08 公開日 2020-03-18 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.7 Å) 主引用文献 Cryo-EM structure of SWI/SNF complex bound to a nucleosome. Nature, 579, 2020
1RNZ	RIBONUCLEASE A CRYSTALLIZED FROM 2.5M SODIUM CHLORIDE, 3.3M SODIUM FORMATE 分子名称: CHLORIDE ION, RIBONUCLEASE A 著者 Fedorov, A.A, Josph-Mccarthy, D, Fedorov, E.V, Sirakova, D, Graf, I, Almo, S.C. 登録日 1996-11-08 公開日 1997-04-01 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Ionic interactions in crystalline bovine pancreatic ribonuclease A. Biochemistry, 35, 1996
5B0Y	Crystal structure of the nucleosome containing histone H3 with the crotonylated lysine 122 分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ... 著者 Suzuki, Y, Horikoshi, N, Kurumizaka, H. 登録日 2015-11-13 公開日 2016-01-27 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.557 Å) 主引用文献 Crystal structure of the nucleosome containing histone H3 with crotonylated lysine 122 Biochem.Biophys.Res.Commun., 469, 2016
8C58	CpG specific M.MpeI methyltransferase crystallized in the presence of 5-hydroxycytosine and 5-methylcytosine containing dsDNA 分子名称: CARBONATE ION, Cytosine-specific methyltransferase, DNA (5'-D(*CP*CP*AP*CP*AP*TP*GP*(5OC)P*GP*CP*TP*GP*AP*A)-3'), ... 著者 Wojciechowski, M, Czapinska, H, Krwawicz, J, Rafalski, D, Bochtler, M. 登録日 2023-01-06 公開日 2024-01-17 最終更新日 2024-09-04 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Cytosine analogues as DNA methyltransferase substrates. Nucleic Acids Res., 52, 2024
8C59	CpG specific M.MpeI methyltransferase crystallized in the presence of 5-bromocytosine (converted to 5mC) and 5-methylcytosine containing dsDNA 分子名称: CARBONATE ION, CITRIC ACID, Cytosine-specific methyltransferase, ... 著者 Wojciechowski, M, Czapinska, H, Krwawicz, J, Rafalski, D, Bochtler, M. 登録日 2023-01-06 公開日 2024-01-17 最終更新日 2024-09-04 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Cytosine analogues as DNA methyltransferase substrates. Nucleic Acids Res., 52, 2024
8C57	CpG specific M.MpeI methyltransferase crystallized in the presence of 5,6-dihydro-5-azacytosine (converted to 5m-dhaC) and 5-methylcytosine containing dsDNA 分子名称: CARBONATE ION, Cytosine-specific methyltransferase, DNA (5'-D(*CP*CP*AP*CP*AP*TP*GP*(5MA)P*GP*CP*TP*GP*AP*A)-3'), ... 著者 Wojciechowski, M, Czapinska, H, Krwawicz, J, Rafalski, D, Bochtler, M. 登録日 2023-01-06 公開日 2024-01-17 最終更新日 2024-09-04 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Cytosine analogues as DNA methyltransferase substrates. Nucleic Acids Res., 52, 2024
3HT8	5-chloro-2-methylphenol in complex with T4 lysozyme L99A/M102Q 分子名称: 5-chloro-2-methylphenol, Lysozyme, PHOSPHATE ION 著者 Boyce, S.E, Mobley, D.L, Rocklin, G.J, Graves, A.P, Dill, K.A, Shoichet, B.K. 登録日 2009-06-11 公開日 2009-11-03 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Predicting ligand binding affinity with alchemical free energy methods in a polar model binding site. J.Mol.Biol., 394, 2009
3HTG	2-ethoxy-3,4-dihydro-2h-pyran in complex with T4 lysozyme L99A/M102Q 分子名称: (2S)-2-ethoxy-3,4-dihydro-2H-pyran, BETA-MERCAPTOETHANOL, Lysozyme, ... 著者 Boyce, S.E, Mobley, D.L, Rocklin, G.J, Graves, A.P, Dill, K.A, Shoichet, B.K. 登録日 2009-06-11 公開日 2009-11-03 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.26 Å) 主引用文献 Predicting ligand binding affinity with alchemical free energy methods in a polar model binding site. J.Mol.Biol., 394, 2009
3HUA	4,5,6,7-tetrahydroindole in complex with T4 lysozyme L99A/M102Q 分子名称: 4,5,6,7-tetrahydro-1H-indole, BETA-MERCAPTOETHANOL, Lysozyme, ... 著者 Boyce, S.E, Mobley, D.L, Rocklin, G.J, Graves, A.P, Dill, K.A, Shoichet, B.K. 登録日 2009-06-13 公開日 2009-11-03 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Predicting ligand binding affinity with alchemical free energy methods in a polar model binding site. J.Mol.Biol., 394, 2009
3HKR	Crystal Structure of Glutathione Transferase Pi Y108V Mutant 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CARBONATE ION, ... 著者 Parker, L.J. 登録日 2009-05-25 公開日 2009-09-22 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Influence of the H-site residue 108 on human glutathione transferase P1-1 ligand binding: structure-thermodynamic relationships and thermal stability. Protein Sci., 18, 2009
6TJM	Crystal structure of an Estrogen Receptor alpha 8-mer phosphopeptide in complex with 14-3-3sigma stabilized by Pyrrolidone1 分子名称: 14-3-3 protein sigma, 5-[(2~{R})-2-(4-nitrophenyl)-4-oxidanyl-5-oxidanylidene-3-(phenylcarbonyl)-2~{H}-pyrrol-1-yl]-2-oxidanyl-benzoic acid, C-terminal phosphopeptide of human estrogen receptor alpha, ... 著者 Andrei, S.A, Bosica, F, Ottmann, C, O'Mahony, G. 登録日 2019-11-26 公開日 2020-04-29 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Design of Drug-Like Protein-Protein Interaction Stabilizers Guided By Chelation-Controlled Bioactive Conformation Stabilization. Chemistry, 26, 2020

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